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Discoid Lupus Erythematosus Clinical Trials

A listing of Discoid Lupus Erythematosus medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 286 clinical trials
B Benjamin F Chong, MD, MSCS

Cutaneous Lupus Registry

Approximately 1.4 million individuals in the United States have systemic lupus erythematosus, and about 85% of these individuals develop skin lesions at some point of their disease. Cutaneous lupus erythematosus represents the skin manifestations of systemic lupus erythematosus, and can appear in people with or without systemic lupus. It is …

18 years of age All Phase N/A
V Victoria P Werth, MD

Prevalence and Clinical Severity of Cutaneous Lupus Erythematosus

The Cutaneous Lupus Erythematosus (CLE) database, established in 2006, is a multi-site database between the University of Pennsylvania and the University of Texas Southwestern (UTSW).

18 years of age All Phase N/A

An Ascending Dose Study of PIT565 in Participants With Systemic Lupus Erythematosus (SLE).

The purpose of the study is to determine the safety, tolerability, and pharmacokinetics of PIT565 in participants with SLE

18 - 75 years of age All Phase 1
D Dimitrios T Boumpas, Professor in Medicine

Does Belimumab Modify the Natural History of SLE? A Propensity Score-matched, Real-world Study

This will be a combined retrospective and prospective cohort study, that will evaluate the incidence of de novo Systemic Lupus Erythematosus major organ manifestations (defined as BILAG A flares) in patients receiving belimumab (Arm A) and compare it to 2 standard-of-care groups (SoC) (Arm B: patients on SoC; Arm C: …

18 years of age All Phase N/A
R Robert Rissmann, PharmD, PhD

Deep Phenotyping of Cutaneous Lupus Erythematosus

Cutaneous lupus erythematosus (CLE) is an autoimmune disease of which the pathogenesis and pathophysiology are not fully understood. Given the complex and heterogeneous character of the disease, identification, and development of specific biomarkers for diagnosis, disease subtyping, disease severity, and treatment response in CLE is challenging. Therefore, the main objective …

18 - 65 years of age All Phase N/A

A Study of GR1803 in Systemic Lupus Erythematosus

to evaluate the safety and efficacy of GR1803 in the treatment of patients with systemic lupus erythematosus

18 - 60 years of age All Phase 1/2

A Study of SCTB35 in Patients with Systemic Lupus Erythematosus

This study is a multicenter Phase Ib/II clinical trial aimed at evaluating the safety, tolerability and efficacy of SCTB35 in patients with systemic lupus erythematosus (SLE).

18 - 75 years of age All Phase 1/2
S Shuhua Qiang

A Study of D-2570 in Patients With Active Systemic Lupus Erythematosus (SLE)

This study is a multicenter, randomized, double-blind, placebo-controlled Phase II clinical trial designed to evaluate the efficacy and safety of D-2570 in the treatment of active systemic lupus erythematosus.

18 - 70 years of age All Phase 2
A Agathe HERB, PharmD

Evaluation of the Cryocheck HexLA Integrated TCA for the Detection of Lupus Anticoagulant

Lupus anticoagulant (LA) testing is performed using two screening tests: activated partial thromboplastin time (APTT) and diluted Russell's viper venom time. If one of the screening tests is positive, a confirmation test based on the same principle is performed. The HUS Hematology Laboratory uses an integrated APTT for LA testing, …

18 years of age All Phase N/A

Evaluate the Efficacy and Safety of Orelabrutinib in Adult Patients With Systemic Lupus Erythematosus

This is a phase IIb, randomized, double-blind, placebo-controlled, multicenter study to evaluate the efficacy and safety of orelabrutinib in adult subjects with SLE who are receiving standard of care (SOC) therapy.

18 - 75 years of age All Phase 2

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