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Pain Clinical Trials

A listing of Pain medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 2,757 clinical trials
N Nipaporn Wannaprom, Dr

Scapular Repositioning for Neck Pain and Scapular Dysfunction

This randomized controlled trial is designed to evaluate the effects of scapular repositioning in individuals with neck pain and scapular dysfunction. The main questions it aims to answer are: Does scapular repositioning reduce neck pain, increase range of motion, and improve joint position sense and pressure pain threshold? Which type …

18 - 59 years of age All Phase N/A
G Gabriel PL Almeida, PhD

Quadriceps Strengthening At Different Angles in Patellofemoral Pain

Introduction: Patellofemoral pain (PFP) is characterized by anterior, retropatellar and/or peripatellar pain during activities such as running, squatting, kneeling, or prolonged sitting. This condition affects approximately 25% of the general population. Given its complex and multifactorial etiology, PFP presents a significant treatment challenge. All clinical practice guidelines recommend strengthening the …

18 - 35 years of age All Phase N/A
M Meir T Marmor, MD

Comparison of Methods for Recording Post Operative Pain

The purpose of the current study is to identify the optimal method of collection of pain intensity data. The study will compare three collection methods: a hand-written pain journal, a smartphone app, and a novel electronic pain recorder device. Patients will be randomly assigned to one of three methods and …

18 years of age All Phase N/A
K Karim Ladha, MD MSc FRCPC

Psilocybin for Enhanced Analgesia in Chronic nEuropathic PAIN

This is a feasibility study to examine the use of use of Psilocybin (magic mushrooms) to alleviate pain in chronic neuropathic pain. While theoretical mechanisms demonstrate promise, there is no clinical evidence. This vacuum of clinical evidence has been occupied by a "psychedelic hype bubble" with media communications touting psychedelics …

18 - 65 years of age All Phase 2

A Study on TLC590 for Managing Postsurgical Pain

This Phase 2 open-label trial investigates the pharmacokinetics (PK), pharmacodynamics, and safety profile of TLC590 across various surgical procedures. Researchers aim to determine the maximum tolerated dose (MTD) of TLC590 via Safety Monitoring Committee (SMC). The study evaluates TLC590 in bunionectomy, laparoscopy-assisted open ventral hernia repair, breast augmentation, abdominoplasty, and …

18 - 70 years of age All Phase 2

SNAG and SNME in Non-Specific Sciatic Pain

This study is designed as a crossover trial. All participants who meet the inclusion criteria and voluntarily agree to participate will be evaluated using the assessment methods detailed below. Subsequently, participants will be randomly assigned into two groups. The first group (Mulligan Concept Group - MCG) will receive the SNAG …

20 - 50 years of age All Phase N/A

Therapy on Perioperative Anxiety and Pain in Patients

This study aims to explore the effects of preoperative education combined with intraoperative music therapy on perioperative anxiety and pain in patients undergoing elective cesarean section. The study subjects were patients scheduled for cesarean section under combined spinal - epidural anesthesia. A prospective study design with random grouping was adopted. …

18 - 40 years of age Female Phase N/A
C Claudia Vila Manes

National Program to Overcome Pelvic Pain studY (POPPY)

A randomized, parallel-group, investigator-blinded, comparative effectiveness trial of a fully remote, videoconference-based pelvic floor yoga program versus a physical conditioning program for women with chronic pelvic pain syndrome.

18 years of age Female Phase N/A
A Aurore Fernandez, MA

Conditioned Open Label Placebo for Postoperative Pain Management

The primary objective is to evaluate the efficacy of two Conditioned Open Label Placebos (COLP): COLP pill and COLP odor to reduce opioid intake for postoperative (thoracic and spinal surgery) pain management compared to the opioid only usual treatment (TAU).

18 years of age All Phase N/A
D DrNadeem Ahmad

McKenzie vs Manual Therapy for Low Back Pain

A comparative study evaluating the effectiveness of the McKenzie technique versus manual therapy in patients with nonspecific low back pain. The study aims to assess which intervention is more effective in reducing pain and improving functional mobility.

35 - 45 years of age All Phase N/A

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