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Pain Clinical Trials

A listing of Pain medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 2,757 clinical trials
A Amyanne Wuthrich, MS BS

VA Transitional Pain Service Study

The VA Community Care Program has provided an important resource to improve access to surgical care for Veterans unable to have treatment at VA Medical Centers (VAMC). However, there is an increased risk of developing chronic opioid use when at-risk surgical patients receive opioids from non-VA providers. A multidisciplinary approach …

18 years of age All Phase N/A
A Anette Aasen, MD

Ropivacaine Concentration and Rebound Pain

The goal of this clinical trial is to see if the concentration of a local anesthetic (ropivacaine) in peripheral nerve block is related to the severness of pain after surgery of distal radius fractures in adults. The main questions it aims to answer are: Is concentration of ropivacaine related to …

18 - 80 years of age All Phase 4
A Amanda J Crawford, MSHS

Acupuncture for Chronic Pelvic Pain

The objective of this study is to determine if alternative pain management strategies, namely acupuncture, may help reduce intensity of female pelvic pain compared to other pain control modalities. This research study will focus specifically on the Dragon's protocol of acupuncture which will seek to alleviate chronic non-endometriosis pelvic pain …

21 - 65 years of age Female Phase N/A
E Elena M Cortizas, MS

Botox for Chronic Pelvic Pain

The purpose of this research study is to find out if precise, targeted injection of botulinum neurotoxin (commonly known as Botox) provides better relief of pelvic floor hypertonicity and pain than the standard method being used. The researchers want to better understand the effects (good and bad) of targeted botulinum …

18 - 75 years of age Female Phase 1
K Kirby Woodall, MD

Intrauterine Device Insertion Pain Management

The goal of this clinical trial is to learn if use of topical benzocaine prior to the injection of lidocaine is effective in decreasing pain experienced during IUD insertion in patients 18 or older. The main question it aims to answer is: Does topical use of benzocaine prior to lidocaine …

18 years of age Female Phase 4
M Michael Spinner, MS

Discogen for Low Back Pain

This study will be a double-blinded, two-arm, prospective, randomized controlled pilot feasibility study in 40 evaluable subjects (20 in each arm) at one study site within the United States. Subjects in Arm 1 will receive unilateral Discogen treatment; subjects in Arm 2 will receive unilateral sham treatment (control). Treatment in …

21 - 75 years of age All Phase N/A
I Isabel Kristan

Psilocybin in Cancer Pain Study

The overall objective of this study is to assess the feasibility, safety and preliminary efficacy of psilocybin-assisted therapy to alleviate opioid-refractory pain in patients with advanced-cancer. The name of the study intervention used in this research study is: Psilocybin (a tryptamine derivative)

18 years of age All Phase 2
E Elsewify

Premedication on Post-endodontic Pain

The goal of this clinical trial is to compare the efficacy of preoperative administration of alpha-chemo-trypsin, ibuprofen, and acetaminophen in managing post-endodontic pain in patients with symptomatic irreversible pulpitis. The main question it aims to answer is: What is the efficacy of preoperative administration of alpha-chemo-trypsin, ibuprofen, and acetaminophen in …

20 - 50 years of age All Phase 3
S Seda Cansu Yeniğün

The Effect of Mobilising Patients Using Nature Sounds on Anxiety, Pain and Stress Levels

The Effect of Mobilization Using Nature Sounds on Patients' Anxiety, Pain and Stress Levels

18 years of age All Phase N/A

Stress and Pain in People Living With HIV

This is a basic human experimental study utilizing 4 groups of individuals with and without HIV and complex morbidities of cannabis use disorder and major depression who will participate in 2 sessions of the Yale Pain Stress Task (YPST) and follow-up phase to assess drug use and mood symptoms.

18 - 68 years of age All Phase N/A

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