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Pain Clinical Trials

A listing of Pain medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 2,820 clinical trials
C Catherine Raynauld

Comparison of the Efficacy of an Empowered Relief Single-Session Versus Standard Care for Reducing Postoperative Pain Following Elective Orthopedic Surgery: A Randomized Controlled Trial

The purpose of this study is to evaluate the efficacy and acceptability of the French-Canadian version of ER compared to standard care in reducing postoperative pain and improving recovery outcomes at 6-week and 3-month follow-ups after elective orthopedic surgery.

18 years of age All Phase N/A
V Vincenzina Lo Re

Personalized High-Definition tDCS Protocols for Chronic Pain Treatment

This study aims to examine the use of neurostimulation as a potential adjuvant treatment for chronic pain. Among neurostimulation techniques, transcranial direct current stimulation (tDCS) represents a promising, yet not fully exploited, option. Recent methodological advances allow for increased intensity and focality of its effects through personalized high-definition tDCS protocols …

18 - 75 years of age All Phase N/A
R Rena E Courtney, PhD

PREVAIL Interdisciplinary Track: A Pragmatic Randomized Clinical Trial

The goal of this clinical trial is to \[primary purpose learn if a team that involves five types of pain specialists (interventional pain, psychology, pharmacy, nutrition, physical therapy) can treat chronic pain in Veterans. The main questions it aims to answer are: Do patients report less pain after six months …

18 years of age All Phase N/A
S Sandra Coste, MD

Impact of QoLibri Medical Device on the Consequences of Chronic Pain: a Randomized Controlled Trial

A superiority study evaluating the impact of the QoLibri Software as Medical Device on functional and psychological consequences of chronic pain in primary care patients. A prospective, cluster-randomized, wait list, controlled multicentre study with the main objective of evaluating the effectiveness of the QoLibri Digital Therapy on Quality of Life …

18 years of age All Phase N/A
E Enrico De Martino, MD

Mechanistic Study of Personalized rTMS in Chronic Pain

Previous research has demonstrated that repetitive magnetic brain stimulation can be an effective adjunctive treatment for several conditions, including chronic pain. However, current stimulation protocols are typically standardized and do not account for individual variability in brain function. This uniform, one-size-fits-all approach results in only about 40% of patients experiencing …

18 - 80 years of age All Phase N/A
N Nita Hoxha, MBA

POP SINGER Pilot Study

Conduct a single-arm pilot study (N = 24) to examine the feasibility and acceptability of the hybrid (i.e., half in-person, half online) POPSINGER group Music Therapy (MT) intervention.

18 years of age All Phase N/A
H Hanna Kalajas-Tilga, PhD

The Effect of Pain Education Group Therapy and Its Impact on Chronic Pain, Kinesiophobia, and Physical Activity

The goal of this clinical trial is to learn if pain knowledge group intervention among chronic pain patients would influence their level of physical activity, pain intensity, depression, kinesiophobia and central sensitization. The main question it aims to answer is: Primary hypothesis: pain education will decrease participants' depression and pain …

16 - 65 years of age All Phase N/A
C Christina Murphy, PhD

SPACE for Youth With Chronic Pain

The primary objective is to assess the feasibility and acceptability of a group-based parent training intervention for parents of youth with chronic pain. Secondary objectives include evaluating changes in child functional impairment, pain intensity, and parent accommodation.

10 - 17 years of age All Phase N/A
J Juan Ignacio Reoyo, doctor

Clinical Trial to Evaluate the Efficacy and Safety of Platelet-rich Plasma Infiltration in Chronic Omalgia

The experimental group will receive intralesional injections of platelet-rich plasma, evaluating its ability to relieve pain and provide sustained improvement through biological modulation of the joint and tendon environment. In contrast, the control group will be treated with a combination of betamethasone and ropivacaine, representing the current standard of care …

35 - 75 years of age All Phase 3
J Juan V-M Vicente Mampel, PhD

Managing Chronic Spinal Pain With Exercise and Neuromodulation

Chronic spinal pain is a multifaceted condition frequently characterized by an absence of discernible structural causes, manifesting in symptoms such as significant disability and diminished quality of life. Persistent Spinal Pain Syndrome Type 2 (PSPS-T2) represents a common variant, implicating both peripheral and central nervous system mechanisms. This study investigates …

18 - 70 years of age All Phase N/A

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