Advanced Filters
noise

Pain Clinical Trials

A listing of Pain medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 2,824 clinical trials
D Dingpei Han, PhD, MD

Comparison of Drainage Methods in Minimally Invasive Esophagectomy (DEMURE)

This RCT compares three drainage approaches after minimally invasive esophagectomy (chest tube + thoracic mediastinal drainage tube, thoracic, and abdominal mediastinal drainage tube) to evaluate perioperative outcomes, addressing current evidence gaps in pain and complication profiles.

18 years of age All Phase N/A
M Muhammed A MOL, MD

Investigation of the Effects of Serratus Posterior Superior Intercostal Plane Block and Serratus Anterior Plane Block on Perioperative Analgesia Management in Patients Scheduled for Mastectomy

This study aims to evaluate and compare the analgesic efficacy of two ultrasound-guided regional anesthesia techniques, the serratus anterior plane (SAP) block and the serratus posterior superior intercostal plane (SPSIP) block, in patients undergoing elective mastectomy surgery. Postoperative pain following mastectomy is a common and significant clinical problem that negatively …

18 - 75 years of age Female Phase N/A
B Ban Tsui, MD

Obstetric Placement Study Using EST

Combined spinal-epidural (CSE) is an established technique for providing labour analgesia to obstetric patients which provides rapid onset but unsustained analgesia. The epidural catheter can be used to extend and provide continuous pain relief, however during single-segment needle-through-needle CSE, the catheter is untested. This study aims to confirm placement of …

18 years of age Female Phase N/A
C Christopher Porta, MD

Simethicone as Part of ERAS in Bariatric Surgery Patients

By conducting this study, we hope to assess if simethicone (also known as Gas Relief or GasX) has an effect on improving gas pain and bloating specifically in patients undergoing foregut procedures to include bariatric procedures (sleeve gastrectomy, Roux-en-Y gastric bypass), hiatal hernia, and gastric surgery. The purpose of this …

18 - 89 years of age All Phase 4
M Mostafa Borahay, MD, PhD

Opioid Use After Laparoscopic Salpingectomy

The purpose of this study is to evaluate patient-reported post-operative pain scores following minimally invasive tubal sterilization procedures to determine if a multimodal, non-opioid pain control regimen is non-inferior to a pain control regimen including opioids. The study team hypothesizes that with extensive counseling on pain management, multimodal medication use, …

18 years of age Female Phase 4
D David Stockton, MD, MASc, FRCSC

Prednisone for CRPS in Distal Radius Fracture

Wrist fractures are the most prevalent adult fracture. Complex regional pain syndrome (CRPS) is a common complication that can occur, leading to permanent disability and is costly to the patient and healthcare system. In addition, amidst the opioid epidemic, the risk of increased opioid use in patients with CRPS prompts …

19 years of age All Phase N/A
P Prof Sener

Investigation of the Effects of Kettlebell Training

Kettlebell exercises are seen as one of the approaches that can be used conservatively in individuals with shoulder pain. However, it is still unknown what results it has on its therapeutic effects. These findings highlight the need for higher quality studies evaluating the effects of kettlebell use and exercises for …

18 - 35 years of age All Phase N/A
J Joana Duarte

An N-of-1 Trial of an Internet-delivered CBT Program Based on the Psychological Flexibility Model of Chronic Pain for Cancer-related Difficulties

Chronic pain is a commonly occurring complication of cancer and can have negatively impact day-to-day functioning and well-being. The recommended treatment for all forms of chronic pain is cognitive behavioral therapy (CBT). However, access to this treatment in primary and specialist care is limited, including access to specialist pain clinics …

18 years of age All Phase N/A
S Stacey Schulberg

Developing a Brief Intervention to Communicate Cardiovascular Risk to Patients Presenting to the Emergency Department With Chest Pain: a Co-Production Approach. Phase 2.

Some patients who come to the emergency department with chest pain and have not had a heart attack, are at an increased risk of having a heart attack in the future. The investigators know this by taking a blood test (troponin) which looks at damage to the patient's heart. These …

18 years of age All Phase N/A
K Karina Gritsenko, MD

A Prospective Study to Evaluate the Efficacy of Iovera Lumbar Medial Branch Cryoneurolysis Versus Radiofrequency Ablation for the Treatment of Chronic Low Back Pain

A research study is being conducted to compare two treatments for long-term low back pain: One uses the iovera° system, which applies cold to certain nerves in the lower back. The other is the standard treatment called radiofrequency ablation, which uses heat. The primary objective is to find out which …

18 years of age All Phase N/A

Simplify language using AI