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Pain Clinical Trials

A listing of Pain medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 2,736 clinical trials
M Marie-Laure Bouchy Jacobsson

Procedural Sedation and Analgesia for Treatment of Adults With Fractures and Dislocations in the Emergency Department

The goal of this observational study is to evaluate the effectiveness and safety of different procedural sedation and analgesia methods used for adults with painful fractures requiring reduction treatment in the emergency department. The main questions it aims to answer are: Which sedation and analgesia methods provide the best patient …

18 years of age All Phase N/A
A Annisa Annisa, Anesthesiologist

Analgesic Efficacy of Combined PECS II and PIP Block Versus Thoracic Paravertebral Block Post-Mastectomy

Postoperative pain management is crucial for patients undergoing mastectomy for breast cancer. Regional analgesia techniques, such as the Thoracic Paravertebral Block (TPVB), are commonly used to reduce pain and opioid consumption; however, TPVB carries potential risks, including pneumothorax. Interfascial plane blocks, specifically the Pectoral Nerve II (PECS II) block combined …

18 - 60 years of age Female Phase N/A
M Mohamed Morsi, M.B.B.CH

Low-Volume Pericapsular Nerve Group (PENG) Block With Dexamethasone vs Standard-Volume PENG Block After Total Hip Arthroplasty

The goal of this clinical trial is to compare two regimens of the pericapsular nerve group (PENG) block, an ultrasound-guided injection of local anaesthetic targeting the nerves supplying the front of the hip joint, for postoperative pain relief and quadriceps muscle function in patients undergoing primary unilateral total hip arthroplasty …

50 - 70 years of age All Phase 4
S Sofie Rummens, MD

Effect of an Interdisciplinary Spine Rehabilitation Program

The goal of this research project is to evaluate the effectiveness of the current interdisciplinary rehabilitation program (Revita) and follow-up trajectory for chronic lumbar spine disorders in the University Hospitals Leuven.

18 years of age All Phase N/A
R Rishi Singh, M.D

Dextenza in the Post-op Management of Vitreoretinal Surgeries

This study will assess the control of inflammation at days 1, 7, 14, and 21 days following the vitreoretinal surgical procedure analyzing two randomized study arms: Intracanalicular dexamethasone insert group or topical steroid drop group. Patients must be 18 years of age and older, of any race and either sex, …

18 years of age All Phase 4
R Renaud URBINELLI

Observational Study of OROSEDAL in Sore Throat and Minor Oral Lesions

This prospective, multicenter, national, observational, non-interventional post-market clinical follow-up study will evaluate the performance and safety of OROSEDAL in children and adults with sore throat or minor oral lesions, including minor aphthous ulcers and histologically confirmed oral lichen planus. OROSEDAL is prescribed in routine practice before inclusion. Patients will be …

8 years of age All Phase N/A
T Ting-Yu Huang, DDS

Machine Learning for Evaluating and Diagnosing Temporomandibular Disorders

This study aims to improve clinical efficiency and effectiveness in treating Temporomandibular Disorders (TMD). The researchers will integrate machine learning technology with clinical examination data, CBCT, and MRI to identify the core underlying issues of each patient. Based on this precise, AI-assisted diagnosis, the study will implement a tailored treatment …

18 - 70 years of age All Phase N/A

A Clinical Trial to Evaluate the Effects of a Supplement on Gut Health

This study will evaluate the effects of the Peachbiotic supplement on gut health in adults experiencing gastrointestinal symptoms. The trial is a single-arm, open-label, virtual study in which all 40 enrolled participants will use the test product daily for 12 weeks. Participants will take one capsule of the product once …

18 - 60 years of age All Phase N/A
I Ivan Alfredo Huespe, MD, MPh

Cryotherapy Versus Standard Care in Reducing Opioid Consumption After Total Knee Arthroplasty

The goal of this clinical trial is to learn if compressive cryotherapy can reduce postoperative opioid consumption in patients undergoing primary total knee arthroplasty. It will also evaluate whether compressive cryotherapy improves postoperative recovery compared with standard care using conventional ice application. The main questions it aims to answer are: …

18 years of age All Phase N/A
D Daniel Glick

Feasibility of Hyivy Device Post-Radiation for Pelvic Malignancies

Vaginal dilator therapy (VDT) with static dilators is often prescribed to patients following vaginal or pelvic radiation therapy. This study seeks to evaluate the feasibility of a novel intravaginal device that delivers patient-controlled dilation (Hyivy device). The study is designed as a proof-of-concept single-arm pilot study. The primary objective is …

18 years of age Female Phase N/A

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