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Pain Clinical Trials

A listing of Pain medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 2,824 clinical trials
B Benjamin Provencher, D.C., M.Sc.

The METRIC Study Protocol

The goal of this clinical trial is to test the effects of spinal manipulative therapy in individuals with chronic primary low back pain and determine the neurophysiological mechanisms underlying pain relief. The main questions it aims to answer are: • Is pain relief produced by spinal manipulative therapy in patients …

18 - 60 years of age All Phase N/A
J Jodi M Gilman, PhD

Cannabidiol for Reduction of Brain Neuroinflammation

This study will investigate whether cannabidiol (CBD), the primary centrally and peripherally active non-intoxicating compound in the cannabis plant, exerts anti-neuroinflammatory effects in patients with chronic low back pain (cLBP) with or without mild-to-moderate depression.

18 - 75 years of age All Phase 2
M Mohammad Ali, MPhil

Implementation of the Specific Treatment Of Problems of the Spine Approach in Bangladesh

The goal of this implementation trial is to evaluate the clinical outcomes associated with usual physiotherapy care compared to individualized physiotherapy in accordance with the Specific Treatment of Problems of the Spine (STOPS) approach in patients with chronic low back pain (CLBP). The main questions it aims to answer are: …

18 - 65 years of age All Phase N/A
S Sverre M Mjønes, MD

The Lumbar Interbody Fusion vs. Multidisciplinary Rehabilitation (LIFEHAB) Trial

The goal of this randomized controlled trial is to compare lumbar interbody fusion surgery with multidisciplinary rehabilitation in participants aged 20-65 years with persisting (≥ one year) low back pain. The main question it aims to answer is: • Is lumbar fusion surgery superior to multidisciplinary rehabilitation in alleviating persisting …

20 - 65 years of age All Phase N/A
A Arnold Wong, PhD

Acceptance and Commitment Therapy Plus Exercise for Older People With Chronic Low-back Pain: A Pragmatic Cluster Randomised Controlled Trial

Low back pain (LBP) is the fifth-most common disorder among older adults 60 years or older. The prevalence of LBP increases with age, with the highest prevalence occurring at 85 years old. Because many older individuals face various age-related life challenges (e.g., comorbidities, financial difficulties, and bereavement), the addition of …

60 years of age All Phase N/A
L Lise Laclautre

Motivations, Obstacles and Opportunities for Using a Health Application to Encourage Physical Activity in People With Chronic Low Back Pain

In industrialized countries, low back pain can be considered a priority health issue. Some studies define it as one of the leading causes of disability in people under 45, or the leading cause of musculoskeletal disorders, with a prevalence of 26.9%. Chronic forms account for less than 10% of acute …

18 years of age All Phase N/A
D Daniel Whibley, PhD

Clinician Satisfaction With the VERABAND™

The VERABAND™ is a newly-developed, disposable, wearable activity monitor. The researchers will assess clinician satisfaction with the usability and likelihood of clinical adoption of the newly-developed, disposable, wearable activity monitor, across multiple clinical sites in the chronic low back pain (cLBP) population.

18 - 85 years of age All Phase N/A

Evaluation of Multi-Tined Expandable Electrode (MEE) Efficacy and Safety in Treatment of Lumbar Facet Arthropathy by Radiofrequency Neurotomies Compared to Conservative Medical Management.

The purpose of this study is to better understand how people feel after a radiofrequency ablation standard of care surgery using a different type of needle (multi-tined expandable electrode/MEE) in comparison to receiving conventional medical management (CMM) techniques.

18 years of age All Phase N/A
N Nesma M Allam, PhD

Lumber Stabilization Exercise Versus Back Endurance Exercise Among Female University Students

Low Back Pain (LBP) as estimates show that up to 84% of adults will experience LBP at some point in their lifetime, ranking it as a leading cause of disability globally. If the pain lasts more than 12 weeks and remains difficult to manage effectively, it can be called Chronic …

18 - 24 years of age Female Phase N/A
R Robert Joyner, Ph.D.

Improving Health for Patients With Chronic LBP in Rural Communities Through Telerehabilitation

Physical therapy is the first line of treatment for patients with low back pain (LBP) and has been shown to be a cost-effective method for improving pain and disability in patients with chronic LBP; however, despite this effectiveness, only 7-13% of patients go on to receive physical therapy services with …

18 years of age All Phase N/A

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