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Pain Clinical Trials

A listing of Pain medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 2,820 clinical trials
J Jonas Verbrugghe, PhD

Technology Supported High Intensity Training in Chronic Low Back Pain: the Techno-HIT Trial

Chronic low back pain (CLBP) is one of the most common chronic musculoskeletal disorder worldwide and is responsible for the highest levels of disability of all diseases. All state-of-the-art guidelines recommend implementing exercise therapy (ET) in CLBP management. Researchers have shown that a novel ET modality, namely high intensity training …

18 - 65 years of age All Phase N/A
z zeinab Awadallah

High Tone Power Therapy Versus Transcutanuoselectrical Nerve Stimulation on Polyneuropathic Pain in Diabetic Patients

the results of this study may provide an easy non pharmacological modality for dealing with diabetic polyneuropathic pain. Also, the outcome of this study will guide physiotherapists to develop a new noninvasive treatment modality that may improve patient symptoms and promotes their social participation , this in turn may add …

50 - 60 years of age Male Phase N/A
L Lasse Visby, Medical Doctor

High Dose Dexamethasone to Reduce Postoperative Pain After Video-Assisted Thoracoscopic Surgery Lobectomy /Segmentectomy

The aim is to conduct a randomized controlled trial (RCT) with a high dose arm (1mg/kg) vs a low dose (8mg in total) of steroid (Dexamethasone) given intravenous (IV) after the induction of anesthesia to "High-pain-responders" in patients undergoing VATS lobectomy/segmentectomy. The hypothesis is that a high dose of Dexamethasone …

18 years of age All Phase 2/3
I Inge Geraerts, Prof, PhD, PT

Proprioceptive, Fear-related and Inflammatory Factors in the Persistence of Pregnancy-related Lumbopelvic Pain.

Pregnancy-related lumbopelvic pain (PLPP) affects 50-90% of pregnant women and is often dismissed as a normal part of pregnancy. However, the long-term consequences can be dramatic. Up to 21% of women with PLPP still have pain three years postpartum, and 10% experience disability, poorer quality of life, and lower ability …

18 - 40 years of age Female Phase N/A
F Francisco de Asís Fernandez

Moderate-Intensity Exercise and Pain Sensitization in Breast Cancer Survivors: A Case-Based Study

The aim of this study was to evaluate the feasibility, safety, and acceptability of a supervised, combined moderate-intensity aerobic and resistance training program designed to reduce pain sensitization in BCS with persistent pain. Secondary objectives included assessing changes in pain intensity, somatosensory sensitivity, and temporal summation, while tertiary objectives focused …

years of age Female Phase N/A
K Kristian Hermander, Nurse anesthetist

Virtual Reality (VR) Could Be a Good Alternative to Relaxing or Pain-relieving Medication

We want to investigate whether Virtual Reality (VR) could be a good alternative to the relaxing or pain-relieving medications that are often used to alleviate anxiety when patients undergo surgery under local anesthesia.

65 years of age All Phase 4
Z Zoya Haitov Ben Zikri, MD

Effect of Ketalar or Dexmedetomidine on Increased Sensitivity to Pain Following Treatment With Remifentanil

Analgesia is one of the pillars of anesthesia. One of the common opiates for pain relief, with a short half-life, is Remifentanil. However, following Remifentanil treatment an increased sensitivity to pain \[hyperalgesia\] appears. The aim of the study is to compare the effects between complementary treatments, like Ketalar and Dexmedetomidine, …

18 - 85 years of age All Phase N/A

Effect of MET vs Neck Calliet Exercises on Neck Pain and Disability in Nurses

This study compares the effectiveness of Muscle Energy Techniques (MET) and Neck Calliet Exercises in managing mechanical neck pain and associated disability due to trapezius trigger points among nurses. A total of 38 female nurses were randomly assigned to two intervention groups, each receiving therapy for four weeks. Pain, cervical …

18 - 30 years of age Female Phase N/A
V Veronica de Flon

Botulinumtoxin A as a Treatment for Myalgia and Myofacial Pain in Patient With Temporomandibulardisorders

Both patients and remitters ask for treatment with Botulinumtoxin A (BTX) with the hope that it will be an effective aid for pain, but little is known regarding if the effect is dose dependent. The aim of this project is to investigate if injections with BTX in the masseter- and …

18 - 50 years of age Female Phase 3
K Katherine A Scott, BSN

Estradiol-mediated Inflammation and Central Sensitization in the Pathophysiology of Endometriosis-associated Pelvic Pain

The purpose of this study is to better understand how hormone suppression with Relugolix Combination-Therapy (CT) affects pelvic pain, inflammation, and pain sensitivity in women with moderate-to-severe endometriosis associated pelvic pain.

18 - 49 years of age Female Phase 3

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