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Pain Clinical Trials

A listing of Pain medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 2,820 clinical trials
M MANISHA P SHENOY, Masters

Effects of PEMM in Chronic Low Back Pain Women With Urinary Incontinence

Urinary incontinence (UI), Chronic low back pain (CLBP) in women are prevalent and often coexist. Multiple conditions when coexist, it leads to reduced Quality of life in turn causing physical and mental impairment. Musculoskeletal structures and fascial restrictions is one of the attribute to the coexistence of urinary incontinence and …

18 - 65 years of age Female Phase N/A
G Gulcan HARPUT, PROF. DR.

Effects Exercises in Temporomandibular Joint Disorders on Pain, Joint and Tongue Functions

The goal of this clinical trial is to learn if orofacial exercises works to treat temporomandibular disorders in adults. It will also learn about the safety of orofacial exercises on temporomandibular disorders. The main questions it aims to answer are: Does orofacial exercises improve function of temporomandibular disorders ? Does …

18 - 65 years of age All Phase N/A
B Ben Lightowler, MSc

Investigating the Role of Central Pain Hypersensitivity in Skeletal Muscle Neural Drive

Background: pain lasting for 12 weeks or beyond, which is often referred to as chronic pain, is common for people living with musculoskeletal conditions (e.g. arthritis, low back pain and fibromyalgia). Pain is often not directly related to the degree of muscle or joint damage. Adaptations of the central nervous …

40 years of age All Phase N/A
L Lena Anna Gschwandtner, Doctoral candidate

Development of a Patient-Centered Assessment Tool for Pain During Cesarean Delivery

This study aims to develop a standardized tool to assess intraoperative pain during cesarean delivery under neuroaxial anesthesia. The tool will draw on existing scientific literature, expert clinical opinion and the experiences of patients who have recently undergone caesarean delivery. Experts from multiple disciplines will participate in a structured consensus …

18 years of age Female Phase N/A
H Himani Bhatt, DO

Suzetrigine for Treatment and Reduction of Intense Discomfort After knEe Replacement PAIN

This is a prospective, randomized study. The purpose of this study is to evaluate if the addition of Suzetrigine, a new pain medication, to well established peri-operative pain regimen used for total knee replacement surgery will effect pain control. Does Suzetrigine given pre-operatively decrease the total opioid consumed after total …

18 - 85 years of age All Phase 3

Sodium Aescinate for the Treatment of Low Back Pain (LBP) in Adults

The goal of this clinical trial is to assess the clinical efficacy and safety of sodium aescinate in treating low back pain (LBP) in adult participants.

18 - 65 years of age All Phase 1

A Study of LY4515100 in Participants With Pain Following Third Molar Removal

The purpose of this study is to evaluate the safety and efficacy of LY4515100 and see how a single oral dose compares with placebo in acute postsurgical pain after removing impacted third molars. For each participant, the study may last approximately 6 weeks and will include a stay in a …

18 - 40 years of age All Phase 2
o olfa KAABACHI, MD

Lumbal Erector Spinae Plane Block for Pain Management After Total Hip Arthroplasty

The Erector Spinae Plane (ESP) block or spinal erector block was first described in September 2016 by a Canadian team. It's a block that was initially used for the treatment of chronic thoracic neuropathic pain. The ESP block is one of the inter-fascicular blocks and it's an easy-to-perform technique.In the …

18 - 85 years of age All Phase N/A
S Sarah Kelleher, PhD

Cognitive Behavioral Theory-assisted Virtual Reality for Chronic CANcer Pain (VR-CAN)

While chronic cancer pain affecting as many as 75% of patients is typically addressed using pharmacologic interventions, experts and patients alike support maximizing any relevant non-pharmacologic interventions as well, such as cognitive behavioral therapy. Virtual reality, a novel technology that can temporarily immerse users in a calm, pleasant environment, has …

18 years of age All Phase N/A
J Jenna E Williams, MA

Peripheral Nerve Stimulation With the SPRINT® System in Chronic PSIJC Pain

Chronic lower back pain is a significant cause of disability, affecting 21-68% of people 60 years of age and older (source). Of these cases, 15-30% are attributed to posterior sacroiliac joint complex (PSIJC) pain (source), making it a target for treatment. Peripheral Nerve Stimulation (PNS) is a procedure that involves …

18 years of age All Phase N/A

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