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Pain Clinical Trials

A listing of Pain medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 2,747 clinical trials
K KIT HANG MR KWAN, Advanced Practice Nurse

Effects of Mobile-based Mindfulness Intervention to Reduce Preoperative Anxiety for Patients Undergoing Elective Surgery

This study is a pilot randomized controlled trial (RCT) conducted at Tin Shui Wai Hospital to evaluate the effectiveness of a mobile-based mindfulness intervention in reducing preoperative anxiety among patients scheduled for elective surgery. Aim: To determine if a 4-week mindfulness program delivered via a mobile app can reduce preoperative …

18 years of age All Phase N/A
C Czarina Weinz

Effects of Oral Tranexamic Acid Following Total Knee Arthroplasty

The primary purpose of this study is to evaluate postoperative pain. Secondary outcomes evaluated in this study will include range of motion (ROM), opioid consumption, and ambulation. Each outcome measure will be evaluated, oral tranexamic acid (TXA) in the experiment arm and placebo in the control arm, after total knee …

18 - 89 years of age All Phase 2
m mostafa tairy adam, md

Femoral Nerve Block, Periarticular Nerve Group (PENG) Block, and Preoperative IV Fentanyl

The pericapsular nerve group block is a regional anesthetic technique described in 2018, developed primarily in total hip arthroplasties for postoperative analgesia with motor sparing benefits. The block is thought to provide more complete analgesia to the hip by depositing local anesthetic within the myofascial plane of the psoas muscle …

55 - 69 years of age All Phase N/A
E Emine Ozcan, MD

Effects of TAP and QLB-1 Blocks on Opioid Consumption

Laparoscopic cholecystectomy is associated with less pain than open surgery and a shorter recovery time. While the type of pain experienced after laparoscopy differs from that experienced after laparotomy, it is predominantly parietal pain (originating from the abdominal wall). However, patients also report visceral pain due to pneumoperitoneum. Various analgesic …

18 - 64 years of age All Phase N/A
X Xinli Ni, MD

Effect of Posterior Femoral Cutaneous Nerve Block on Postoperative Posterior Lateral Knee Analgesia in Patients With TKA

The aim of this study was to observe the effects of posterior femoral cutaneous nerve block combined with sciatic and saphenous nerve block compared with sciatic and saphenous nerve block alone on postoperative posterior side of the knee (popliteal fossa) pain and sleep quality in patients with TKA, and to …

45 - 80 years of age All Phase N/A
M Martin Beaumont

Paravertebral Block for Mastectomy with Immediate Reconstruction

Following a mastectomy, patients may develop chronic pain, called post-mastectomy pain syndrome (PMPS). This syndrome manifests itself as complex neuropathic pain that seems linked to nerve damage suffered either during surgery, during healing or by nervous system dysfunction. However, the exact pathophysiology remains unknown. Typically, the pain is located on …

18 - 70 years of age Female Phase N/A
w wenying wu

Efficacy and Safety of Oliceridine for Moderate to Severe Acute Pain After Orthopedic Surgery

The goal of this clinical trial] is to further explore the effectiveness and safety of oxelidine in the treatment of moderate to severe acute pain after orthopedic surgery. The main question it aims to answer is: Pain management after orthopaedic surgery provides more effective and safe drug options, provides new …

18 - 100 years of age All Phase 4
G Gabriel Frimpong, MPH, PA

RADA16 for Adult Tonsillectomy

The purpose of the research is to determine if RADA16 (also known as PuraStat®, PuraGel®, or PuraSinus®) improves patient outcomes following tonsillectomy procedures. Researchers will compare application of device RADA16 to application of no device to see if RADA16 works to treat post tonsillectomy hemorrhage. Participants will: Undergo tonsillectomy procedure. …

18 years of age All Phase 3
L Li Fang Wang, MD

Outcomes for Anesthesiologist-Led Care of Analgesic Protocol in Anorectal Surgery

This will be an open, prospective, parallel-group, randomized controlled trial. Patients scheduled for complex anorectal surgery under general anesthesia will be enrolled, and the perioperative analgesia mode led by anesthesiologists will be established. Compared with the perioperative analgesia mode led by surgeons, the efficacy and safety of analgesia, quality of …

18 - 85 years of age All Phase N/A

Ultrasound-Guided QL Block Versus TAP Block For Post-Operative Pain In Lower Abdominal Surgeries

This study aims to compare the efficacy of ultrasound-guided QL block and TAP block for postoperative pain management following lower abdominal surgeries.

18 - 65 years of age All Phase N/A

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