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Pain Clinical Trials

A listing of Pain medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 2,820 clinical trials

EFFECT OF SAPHENOUS NERVE RELEASE ON PATIENTS WITH PATELLOFEMORAL PAIN SYNDROME

Patellofemoral Pain Syndrome (PFPS) is a frequent cause of anterior knee pain in young, physically active individuals, especially females, and is commonly managed with quadriceps and hip-focused exercises. However, the role of neural factors has been largely overlooked. The saphenous nerve, which supplies sensation to the anteromedial knee, may become …

18 - 35 years of age All Phase N/A
Q Qurat ul ain Sara Ahmed, DPT

Non-Thrust Lumbar and Sacral Mobilizations in Mechanical Low Back Pain

This study is a randomized controlled trial and the purpose of this study is to determined the effects of sacral mobilizations along with the lumbar mobilizations in mechanical low back pain on components such as pain , lumbar range of motion, lumbar proprioception and functional disability.

18 - 45 years of age All Phase N/A
H Helen Lavretsky, MD, MS

A Randomized Pilot rTMS Trial for Knee Arthritis Pain and Depression

Osteoarthritis (OA) is a major public health problem, and involvement of the knee is especially disabling. Symptomatic knee OA has an incidence rate between 40 to 1,020 per 100,000 person years1 and is among the most common causes of disability worldwide. Knee arthritis pain and disability are highly comorbid wiht …

50 - 95 years of age All Phase 0
z zongyou pan, Doctoral degree

Preop US-Guided Nerve Blocks for Pain & Recovery After Ankle Arthroscopy

This randomized, double-blind controlled trial investigates the effectiveness and potential trade-offs of preoperative ultrasound-guided popliteal sciatic and saphenous nerve blocks in patients undergoing ankle arthroscopy, a procedure often performed in day-case settings but associated with significant early postoperative pain and frequent opioid use. The study evaluates whether these nerve blocks …

18 - 65 years of age All Phase N/A
K Krystian Mleczko, Msc

Evaluation of Stabilization Training With Biofeedback in Lumbosacral Spine Pain Syndrome

The aim of the study is to evaluate the effects of biofeedback-assisted stabilization training and conventional therapy on pain perception, balance, spinal mobility, functional performance, physical activity, stress level, and quality of life in patients with lumbosacral spine pain syndrome treated conservatively. The main research questions the study seeks to …

30 - 65 years of age All Phase N/A

Investigation of Pain Perception According to Gender in Individuals With Scoliosis

The aim of this study is to evaluate whether pain perception under spinal pressure created on a physiotherapy roller differs according to gender in individuals diagnosed with scoliosis.

18 - 45 years of age All Phase N/A
M Malin Ernberg

Peripheral TMD Pain Mechanisms and the Effect by Botulinum Toxin A

The goal of this clinical trial is to investigate the effect of botulinum toxin on neurons' plasticity in the masseter muscle in humans with and without painful myogenous temporomandibular disorders (TMDM). The main questions it aims to answer are: does treatment with botulinum toxin alter gene expressions, epigenetic signatures, and …

20 - 45 years of age Female Phase 2
H Hüdanur Coşkun, M.D.

Effects of Close Follow-up on Patients With Low Back Pain

This study will include patients aged 18-65 with subacute or chronic mechanical low back pain who apply to the Physical Medicine and Rehabilitation Clinic. The age, gender, body mass index, duration of low back pain, smoking status, and educational status of the patients included in the study will be recorded. …

18 - 65 years of age All Phase N/A
D Dr Thomas MD, MD

Adia Med of Winter Park LLC Lower Back Pain Research Study

The goal of this clinical study is to evaluate the safety and preliminary efficacy of an investigational umbilical cord blood-derived stem cell and exosome infusion in adults with chronic lower back pain associated with degenerative spine disease. The primary questions this study aims to answer are whether the investigational infusion …

18 - 85 years of age All Phase 1
b bouchra benkessou, chef de projet

Evaluation of the Effect of Reiki on Pain After Lumbar Surgery

The goal of this clinical trial (prospective, comparative, and randomized double-blind study) is to learn if Reiki (a non-pharmacological intervention), when used alongside standard care, can treat and reduce postoperative pain in patients recovering from lumbar surgery (60 participants total, divided into two groups of 30). The main questions it …

18 years of age All Phase N/A

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