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Pain Clinical Trials

A listing of Pain medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 2,820 clinical trials
P Patricia PT TEJEDOR

Pain Evaluation Across Robotic and Laparoscopic Surgery for Colorectal Procedures

Minimally invasive surgery for colorectal conditions, such as laparoscopic or robotic surgery, has been shown to offer benefits over traditional open surgery. These benefits include less pain after surgery, shorter hospital stays, and fewer complications. This study aims to compare two types of minimally invasive surgery-laparoscopic and robotic surgery-to determine …

18 years of age All Phase N/A
Ö Ömer Taylan S Akkaya

Effect of Additional Sural Nerve PRF in Chronic Heel Pain

This observational study aims to compare the effectiveness of pulsed radiofrequency (PRF) treatment applied to the posterior tibial nerve alone versus PRF applied to both the posterior tibial and sural nerves in patients with chronic plantar heel pain. Outcomes will be assessed using the Visual Analog Scale (VAS) and the …

18 - 65 years of age All Phase N/A
H Haley Nitchie, MHA

Methadone in TKA for Post-op Pain and Opioid Reduction

This randomized, double-blind controlled trial investigates whether intraoperative IV methadone (0.15 mg/kg based on ideal body weight) reduces acute postoperative pain and opioid consumption in patients undergoing elective total knee arthroplasty under spinal anesthesia with mepivacaine.

18 - 75 years of age All Phase 3
S Sara J Sevilla Ardon, MD

Transcutaneous Electrical Nerve Stimulation (TENS) for Pain Management During Labor.

This is a randomized, double-blind, crossover clinical trial to evaluate the efficacy of transcutaneous electrical nerve stimulation (TENS) as a non-pharmacological therapeutic intervention for reducing pain in women during the active phase of labor. Nulliparous women with term pregnancies will be randomly assigned to sequences involving TENS intervention and placebo …

18 - 45 years of age Female Phase N/A
J Jie Chen

MBM and taVNS for Low Back Pain and Depressive Symptoms

This two-arm randomized controlled trial aims to test the preliminary effect of home-based mindfulness-based meditation and transcutaneous auricular vagus nerve stimulation on managing pain and depressive symptoms among community-dwelling older adults with chronic low back pain and depressive symptoms; and the effect of home-based mindfulness-based meditation and transcutaneous auricular vagus …

50 - 85 years of age All Phase N/A
D Dmytro Dmytriiev, MD, PhD, Dr.med.science

Neuroma-Associated Pain Management After Combat-Related Trauma in Ukraine

This multicenter interventional study in Ukraine is designed to compare the effectiveness of cryoablation and radiofrequency ablation in managing neuroma-associated pain following combat-related trauma. Adult patients with clinically significant neuropathic pain caused by neuromas will be randomly assigned to receive either image-guided cryoablation or radiofrequency ablation of the affected nerve. …

18 years of age All Phase N/A
N Nya Robinson

A Superiority Trial of Radiofrequency Ablation for Low Back Pain

The purpose of the ASTRAL Study is to evaluate the effectiveness of LRFA (Lumbar radiofrequency ablation) against a control procedure. The ASTRAL Study will enroll individuals with chronic low back pain (CLBP) and randomly assign them to one of three groups: lumbar radiofrequency ablation using conventional electrodes placed parallel to …

18 years of age All Phase N/A
E Emily Lindley, PhD

Safety and Efficacy of Oral Cannabis in Chronic Spine Pain

The overall objectives of this study are to investigate the efficacy of extended cannabis treatment to reduce patient exposure to prescription opioids through its use 1) as a non-opioid analgesic treatment, and 2) as a therapy for reducing high-dose opioid use in patients with chronic spine pain.

21 - 84 years of age All Phase 3
M Merve Firat, Assistant Professor

The 6 Minute Step Test in Chronic Low Back Pain

Our study aimed to investigate whether the 6 minute step test could be used as an alternative to the 6 minute walk test for assessing functional capacity in individuals with chronic low back pain.

18 - 65 years of age All Phase N/A

Effect of TENS on Pain and Symptoms in Primary Dysmenorrhea

The Effect of Transcutaneous Electrical Nerve Stimulation (TENS) on Pain and Menstrual Symptoms in Primary Dysmenorrhea This study aims to investigate the effectiveness of Transcutaneous Electrical Nerve Stimulation (TENS) in managing pain and alleviating menstrual symptoms in individuals with primary dysmenorrhea. Primary dysmenorrhea is characterized by severe menstrual pain and …

18 years of age Female Phase N/A

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