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Pain Clinical Trials

A listing of Pain medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 2,747 clinical trials

Burst Crossover Trial

Spinal cord stimulation (SCS) is a widely applied therapy to treat chronic neuropathic pain, and one of the most common indications is persisting radicular neuropathic pain following lumbar spine surgery. In traditional SCS therapies, the objective has been to replace the pain sensation with paresthesia. The anticipation is that the …

18 years of age All Phase N/A
K Kawal P Singh

End-on Versus Parallel Radiofrequency Lesioning for Neurotomy of the Cervical Medial Branch Nerves

Aim of the EndPaRL study is to compare the efficacy and effectiveness of the two techniques utilizing sharp straight conventional radiofrequency needle with a trident needle for radiofrequency neurotomy of Cervical Medial Branch Nerves (CMBNs), in patients presenting with chronic, moderate-to-severe, neck pain due to cervical zygapophyseal joint osteoarthritis, as …

18 - 85 years of age All Phase N/A
P PMR Research Group

Trident Multi-tined Cannula for Cervical MBRFA Compared to the Conventional Cannula

Cervical medial branch radiofrequency ablation (CMBRFA) is an effective treatment for cervical facet pain. The efficacy of CMBRFA was proven by studies published in the late 1990's and early 2000's. Patients were selected by a strict, labor-intensive placebo-controlled, diagnostic block protocol and were treated using a conventional monopolar cannula that …

18 years of age All Phase N/A
F Furqan Yaqoob, MS-OMPT,PHD*

Additional Benefits of Neck Exercises in Addition to Ergonomic Training in Office Workers With Neck Pain

Neck pain is a multifactorial disease and the factors related to neck pain are physical workloads, poor ergonomic work design and certain psychosocial factors. It arises due to disease of cervical spine and soft tissues of the neck, muscle spasm, falling asleep in awkward position, prolong working at computer desk …

25 - 50 years of age All Phase N/A
L Laura López-García

Manual Therapy Effectivity and Exercises in Musicians

Orofacial pain is one of the most common dysfunctions among wind musicians, a population with a high incidence of temporomandibular disorder (TMD). Regarding the treatment of TMD, the efficacy of manual therapy and therapeutic exercise has been studied, but there is a lack of high quality research supporting its implementation. …

18 - 65 years of age All Phase N/A
S Saba Rafique, MSOMPT

Effects of Manual IC With and Without SCS on SCM Tightness With FHP

The aim of this study is to compare the effects of Manual Ischemic Compression with and without Strain Counterstrain technique on CVA, ROM, pain and disability among FHP individuals with SCM tightness.

25 - 40 years of age All Phase N/A
W Wan Ling Leong

Development of Variable Volume Automated Mandatory Boluses for Patient-controlled Epidural Analgesia During Labour

A novel epidural delivery regimen was developed: Variable volume automated mandatory bolus (AMB) (VVAMB) will advance individualisation of labour epidural analgesia, by which a larger volume of bolus may contribute to better spread of the local anaesthetics within brief period and thereby reduces the chances of motor blockade that could …

21 - 50 years of age Female Phase 3

Cervical/Thoracic Neuromodulation and Nociceptive Processing

Several studies have demonstrated that direct currents delivered through the skin at the level of the low-thoracic spinal cord can influence spinal cord function. In human volunteers, anodal low-thoracic transcutaneous spinal direct current stimulation (tsDCS) alters spinal processing of nociceptive inputs. Whether cervical tsDCS is able to do the same …

18 - 40 years of age All Phase N/A
D Daniel A Williams, B.A.

Personalized Repetitive Transcranial Magnetic Stimulation (PrTMS)

This study aims to assess the efficacy of Personalized Repetitive Transcranial Magnetic Stimulation (PrTMS) therapy to reduce chronic neck for military health system beneficiaries.

18 - 65 years of age All Phase N/A
S Stephany Nathe

Normalizing Cervical Intersegmental Kinematics With Spinal Manipulative Therapy

The broad long-term objective is to develop an objective biomarker for spinal health based on aberrant or abnormal movement patterns during functional activities to better target spinal manipulation therapy (SMT) and other conservative treatments. The central hypotheses are a) that aberrant spinal motions and their location (area and level) are …

18 - 39 years of age All Phase N/A

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