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Pain Clinical Trials

A listing of Pain medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 2,825 clinical trials
K Konstantinos Kalimeris MD, PhD, Associate Professor of Anesthesiology

Prolotherapy in Acupoints in Chronic Non-specific Low Back Pain (cLBP)

Chronic non-specific low back pain (CNSLBP) is among the most prevalent causes of disability on the planet, which often proves to be refractory to conventional pharmacological, interventional, and rehabilitation approaches. Although acupuncture has also shown analgesic effectiveness, its variability and reliance on practitioner skill limit its universal introduction into Western …

35 years of age All Phase 0
S Serge Nikolic

EVOKE ECAP-Controlled Lead Placement and Programming in Chronic Pain Patients

This study is designed to evaluate the feasibility of using intra-operative ECAP and Late-Response (LR) recordings for confirmation of activating the neuronal target of the dorsal column in a single-stage SCS lead placement procedure. The collected ECAP and LR data will be analysed post-hoc to further evaluate its utility for …

18 - 75 years of age All Phase N/A

EFFECT OF SAPHENOUS NERVE RELEASE ON PATIENTS WITH PATELLOFEMORAL PAIN SYNDROME

Patellofemoral Pain Syndrome (PFPS) is a frequent cause of anterior knee pain in young, physically active individuals, especially females, and is commonly managed with quadriceps and hip-focused exercises. However, the role of neural factors has been largely overlooked. The saphenous nerve, which supplies sensation to the anteromedial knee, may become …

18 - 35 years of age All Phase N/A
Q Qurat ul ain Sara Ahmed, DPT

Non-Thrust Lumbar and Sacral Mobilizations in Mechanical Low Back Pain

This study is a randomized controlled trial and the purpose of this study is to determined the effects of sacral mobilizations along with the lumbar mobilizations in mechanical low back pain on components such as pain , lumbar range of motion, lumbar proprioception and functional disability.

18 - 45 years of age All Phase N/A

Ibuprofen With or Without Dexamethasone for Acute Radicular Low Back Pain.

This will be a placebo controlled, randomized, double-blind, comparative effectiveness study, in which we patients are enrolled during an emergency department (ED) visit for acute radicular low back pain (LBP) and followed by telephone two and seven days later. Patients will be randomized to receive an oral dose of dexamethasone …

18 - 70 years of age All Phase 4
A Aaron Conger, DO

Conventional vs Bipolar SIJ RFA for Treatment of Sacroiliac Joint Pain

Specific Aims The sacroiliac joint complex (SIJC) is a diathrodial, synovial joint and posterior ligamentous network that receives both anterior innervation from the lumbosacral plexus as well as posterior sensory innervation via the posterior sacral network (PSN). The PSN is comprised by the lateral branches S1-S3 posterior rami, with variable …

18 - 90 years of age All Phase 4
G Graeme Witte

Brain-Based and Clinical Phenotyping of Pain Pharmacotherapy in Knee Osteoarthritis

This is a clinical trial of people who have pain due to knee osteoarthritis at Northwestern University Feinberg School of Medicine. The study will last for about 20 weeks. 180 qualified participants will be randomly assigned in a 1:1:1 ratio (60 participants per group) to one of three treatment groups: …

41 years of age All Phase 4
S Sander Koëter, PhD

Surgery and Exercise Versus Exercise Only for Chronic Patellofemoral Pain Syndrome

The goal of this randomised controlled trial is to compare a tuberositas transposition (TTT) surgery with a home exercise program (HEP) in patients with patellofemoral pain syndrome (PFPS). The study aims to evaluate the efficiency of TTT in conjunction with a HEP compared to a HEP alone in patients with …

18 - 35 years of age All Phase N/A
S Sümeyye Zehra Güler, MSc

Assessment of All Spine Segments ın Individuals With Low Back Pain

The aim of the study is to evaluate the kinematics of all spine segments in 3 planes and compare them with asymptomatic controls using wearable technology while performing functional tasks that patients with chronic low back pain often describe as painful in their daily lives.

18 - 55 years of age All Phase N/A

Phenotyping Response to Spinal Cord Stimulation in Chronic Low Back Pain

Chronic low back pain (CLBP) is a debilitating condition and costly to treat. Long-term drug treatment often fails due to habituation, breakthrough of pain, or adverse effects of drug treatment. Opioid use to manage this pain has contributed to the opioid epidemic. Spinal cord stimulators have emerged as a promising …

18 - 80 years of age All Phase N/A

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