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Pain Clinical Trials

A listing of Pain medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 2,820 clinical trials
G Gabrielle Reichard

Yoga for Back Pain in Adolescent Scoliosis

The Problem: Adolescent Idiopathic Scoliosis (AIS), the pre-eminent spinal pathology affecting over 5% of children and adolescents, presents a pronounced spinal curvature exceeding 10 degrees, with prevalence amongst female adolescents at a ratio of 3:1 compared to males. A significant portion of these patients are not immediate candidates for surgical …

10 - 20 years of age All Phase N/A
C Chwan-Li (Leslie) Shen, PhD

Ginger Root Extract for Sciatic Pain Individuals

Neuropathic pain affects the quality of life of many Americans. Non-pharmacological strategies such as bioactive compounds in foods are being explored as therapeutics but can also serve as tools to better understand pain mechanisms. The previous study reported that ginger root extract supplementation palliated pain-spectrum behaviors in animals with neuropathic …

18 - 85 years of age All Phase 2
B Bodil Ehn, MD

Screening for Pregnancy Related Pelvic Girdle Pain

To perform clinical manual pain provocation tests of the pelvic joints in pain free pregnant women early in pregnancy, follow them until delivery, and compare those who develop PPGP with those who don't.

years of age Female Phase N/A
A Areen Khoury, DMD

Nerve Block Treatment for Chronic Jaw Pain

Study Summary: Nerve Block Treatment for Chronic Jaw Pain This study is being conducted at the TMJ (temporomandibular joint) clinic, which is part of the oral and maxillofacial surgery department. The goal is to evaluate how effective peripheral nerve blocks are in reducing long-term jaw pain in patients with chronic …

18 years of age All Phase N/A
M Mercè Matute, MD, PhD

Chronic Insomnia in Non-Cancer Pain Patients

Pain and sleep are closely linked physiological processes that support overall health and functioning. Increasing evidence shows a dynamic, bidirectional relationship: poor sleep increases pain sensitivity, while chronic pain disrupts normal sleep. Both conditions are highly prevalent and significantly impair quality of life, making them major public health concerns. Chronic …

18 years of age All Phase N/A

Pain and Physical Fitness in Primary Dysmenorrhea

The aim of this study is to evaluate pain and physical fitness parameters such as balance, muscle strength, and core stabilization in primary dysmenorrhea.

18 - 25 years of age Female Phase N/A
H Hernán de la Barra, Mg.

High-intensity Laser Therapy for Neck Pain

Chronic nonspecific neck pain is a common musculoskeletal disorder recognized for its high rates of disability and economic losses, ranking second in musculoskeletal conditions after low back pain. There are several effective physical therapy interventions to treat chronic nonspecific neck pain, such as laser therapy. High-intensity laser therapy (HILT) is …

18 years of age All Phase N/A
M Mohamed ElMeligie, Ph.D

HILT Dose Optimization for Knee Osteoarthritis Pain

This study aims to find the best settings (dose) for High-Intensity Laser Therapy (HILT) to reduce pain and improve function in people with moderate knee osteoarthritis. Participants will be randomly assigned to receive one of three different doses of HILT (low, medium, or high) or a sham (placebo) laser treatment, …

18 - 65 years of age All Phase N/A
J Jakob Kim

Emotion and Memory in Chronic Neuropathic Pain

Chronic pain affects one in four Canadians, leading to severe personal and societal costs. Over 70% of chronic pain patients report memory difficulties and fear having unexpected pain. Abnormalities in brain structures associated with emotion and memory, including the hippocampus and amygdala, can be affected by chronic pain. Understanding the …

35 - 60 years of age All Phase N/A
N Ninni Sernert, PhD

Digital Training Interventions for Low Back Pain

The patients will be clinically examined, as well as evaluated with Patient Reported Outcome Measures (PROMs) and Magnet Resonance Imaging (MRI) at baseline and at follow-ups.

18 - 50 years of age All Phase N/A

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