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Gastroparesis Clinical Trials

A listing of Gastroparesis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 47 clinical trials
Y Yu Wen Tien, Ph.D.

Delayed Gastric Emptying After Pancreatic Surgery

Delayed gastric emptying (DGE) is a common complication of pancreatic surgery. Once it occurs, it often affects the patient's postoperative quality of life and may even delay subsequent necessary treatments, such as adjuvant chemotherapy. Therefore, this project aims to retrospectively collect basic data, preoperative and postoperative blood tests (blood cell …

20 - 75 years of age All Phase N/A
A A. Aziz Aadam, MD

Transpyloric Stenting as a Predictor for G-POEM for Refractory Gastroparesis

This is a prospective sham study to investigate the role of transpyloric stenting with lumen apposing metal stent (LAMS) as a predictor for clinical response to gastric per-oral endoscopic pyloromyotomy (GPOEM) for refractory gastroparesis. The study hypothesizes that clinical improvement with transpyloric stenting in patients with refractory gastroparesis is a …

18 years of age All Phase N/A
J Jan Tack, PhD, MD

Different Doses of Naronapride vs. Placebo in Gastroparesis

This is a double-blind, randomized, multicenter, placebo-controlled, comparative phase II dose-finding trial. The trial will be conducted with four treatment groups in the form of a parallel group comparison and will serve to compare oral treatment with daily doses of 10, 20, or 40 mg Naronapride vs. placebo for the …

18 - 75 years of age All Phase 2

Central and Peripheral Effects of Cognitive Behavioral Therapy on Brain-Gut Axis Signaling in Gastroparetic Patients

This is a single-center pilot study to be conducted at Massachusetts General Hospital. The purpose of this study is to examine the non-pharmacological impact of Cognitive Behavioral Therapy (CBT) on gastroparesis symptoms and other clinical co-comorbidities such as pain, depression, anxiety, and catastrophizing. CBT trial patients will undergo careful phenotyping …

18 - 65 years of age All Phase N/A
D Daphne Foong, PhD

Body Surface Gastric Mapping vs Gastric Emptying Scintigraphy on Clinical Management in Gastroparesis

Gastroparesis is a chronic and debilitating gastric disease associated with poor quality of life, psychological distress, frequent hospitalisations, and high healthcare utilization and associated costs. It is defined by persistent upper gastrointestinal symptoms and delayed gastric emptying with no mechanical gastric outlet obstruction. Gastric emptying scintigraphy (GES) is the current …

18 years of age All Phase N/A
K Kim Sweerts, MD

G-POEM vs PEG-J in Gastroparesis Patients

Study design: A randomized non-blinded controlled clinical trial with two study arms (G-POEM and PEG-J). Treatment success is measured using the GCSI at baseline before intervention and six months after intervention with a possible cross-over after six months of follow-up. Study population: 50 patients with therapy refractory GP on dietary …

18 years of age All Phase N/A
L Lainna Cohen, MSW

The Use of Body Surface Gastric Mapping in Assessing the Clinical Success of G-POEM

The purpose of this study is to investigate whether or not the investigators can utilize Body Surface Gastric Mapping to determine who would best benefit to receive G-POEM procedure and how Body Surface Gastric Mapping can be utilized with patients who have gastroparesis symptoms. the investigators may also be able …

18 years of age All Phase N/A
T Tisha Lunsford, MD

Growth Hormone for the Treatment of Gastroparesis

The purpose of this study is to determine whether treatment with Growth Hormone results in symptomatic improvement in patients with gastroparesis.

18 - 65 years of age All Phase N/A
A Andy Bolender

Vagal Nerve Stimulation for Functional Dyspepsia and Gastroparesis

Explore the effects of auricular transcutaneous vagal nerve stimulation (taVNS) on brain and stomach outcomes in functional dyspepsia and gastroparesis patients.

18 - 70 years of age All Phase N/A
E Elizabeth Meyer, MPH

Brain-Gut Yoga for Functional Dyspepsia and Gastroparesis (FD-GP)

The purpose of this research study is to assess whether using a yoga-based intervention in practice is feasible (possible) and acceptable to patients with Functional Dyspepsia and/or Gastroparesis (FD-GP).

18 years of age All Phase N/A

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