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Esophageal Disorders Clinical Trials

A listing of Esophageal Disorders medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 707 clinical trials
P Patricia Hägglund, PhD/SLP

Dysphagia After Anterior Cervical Spine Surgery

The purpose of this research project is to investigate the incidence of impaired swallowing (dysphagia) after anterior cervical spine surgery (ACSS) and to study the long-term effect of dysphagia on nutritional status 12 ± 3 months later. Furthermore, to investigate the effect of a new rehabilitation method for dysphagia among …

18 years of age All Phase N/A
P PX Wei, Dr.

Developing Effectiveness Evaluation and Therapeutic Programs of Rehabilitation

Using robotics, sensors, and sEMG to develop clinic-oriented quantitative effectiveness evaluation and individualized programs of rehabilitation

18 - 80 years of age All Phase N/A
P Perla Adames-Castillo

The Esophageal String Test as a Diagnostic Screening Tool for Eosinophilic Esophagitis Among Africans With Dysphagia in Mali and the United States

Background Eosinophilic esophagitis (EoE) is a disease that causes inflammation in the esophagus. The esophagus is the tube that moves food from the mouth to the stomach. Diagnosing EoE currently requires a specialized tool called an endoscope. The esophageal string test (EST) is another test; the EST collects fluid from …

18 - 65 years of age All Phase N/A
P Ping Wang, MS

Clinical Efficacy and Mechanism of tDCS for Dysphagia in PD

This study aims to verify transcranial direct current stimulation(tDCS) efficacy for Parkinson's disease (PD)-related dysphagia and its mechanism. Subjects are randomly split into two groups: control (sham tDCS + conventional dysphagia treatment) and experimental (real tDCS + conventional treatment). Assessments will be conducted at baseline, after the completion of intervention, …

18 - 100 years of age All Phase N/A

The Effects of Chin Tuck Against Resistance Exercise on Acute Stroke Patients With Dysphagia

The aim of this study is to investigate the effects of chin tuck against resistance exercise on swallowing function, depression, and quality of life in acute stroke patients with dysphagia.

18 - 100 years of age All Phase N/A
J Jeffrey McKeehan, RN, MSN

Corticosteroids for Post-Extubation Dysphagia

This is a placebo-controlled, double-blind randomized trial of a short course of intravenous corticosteroids for Acute Respiratory Failure Survivors with Fiberoptic Endoscopic Evaluation of Swallowing (FEES) documented laryngeal edema. Study was leveraged using the existing R01 grant infrastructure COMIRB # 21-3873, study design, and research methods. Patients for the study …

18 years of age All Phase 2
l leu k hsun, Master

The Effects of Using Augmented Reality (AR) System to Train Foreign Care Workers.

The aim of this study was to evaluate the effect of augmented reality (AR) system training intervention of foreign care workers on the salivary biomarker and oral function of older people. This randomized controlled trial included experimental group: AR group (EG-A) Video group (EG-B) and control group(CG), respectively. The EG-A …

21 - 65 years of age All Phase N/A
S Saeed Sarwar, MBBS

Outcomes of a Single Chest Drain vs Two Drains

Esophagectomy is a major surgical procedure done for carcinoma of esophagus. Usually bilateral chest tubes are placed in surgery for prevention of fluid accumulation in chest. However such procedure limits patients mobility and increases severity of pain. recent studies suggest that a single drain can be safe and effective. our …

years of age All Phase N/A

Intestinal Low Dose Radiotherapy Combined With Immunotherapy in Immune-resistant Metastatic Malignant Solid Tumors

Preclinical and clinical evidence suggests that intestinal low-dose radiotherapy (ILDR) may enhance antitumor immune responses by modulating the gut microenvironment, thereby improving the efficacy of immune checkpoint inhibitors (ICBs) in refractory solid tumors. Based on these findings, the investigators initiate a multicohort phase II clinical trial to evaluate the clinical …

18 - 80 years of age All Phase 2
M Maureen Schilling

Changes in Esophageal Distensibility With Proton Pump Inhibitors in Patients With Esophageal Eosinophilia: A Pilot Study

This pilot study will explore whether treatment of eosinophilic inflammation in the esophagus is associated with an improved distensibility of the esophagus. Furthermore, previous studies of the esophagus using EndoFlip only measured distensibility of the distal esophagus, specifically the distal esophagus and esophagogastric junction. Eosinophilia in EoE has been demonstrated …

18 - 65 years of age All Phase N/A

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