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Esophageal Disorders Clinical Trials

A listing of Esophageal Disorders medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 722 clinical trials
D David Halafyan, MD

Comparison of Molecular-Genetic Concordance of the Primary Tumor and Brain Metastases of Gastroesophageal Cancers

GENCONCOR-2 is a translational research aimed to compare the molecular profile of primary tumors and their matched brain metastases in gastroesophageal cancers, including cancer of the esophagus, gastroesophageal junction, and stomach. The study is based on the previously established international GASTROBRAIN cohort (ClinicalTrials.gov ID: NCT07448493), which provides comprehensive clinicopathological and …

18 years of age All Phase N/A

Impact of Body Positioning on EndoFLIP Measurements: A Comparative Study of Supine and Left Lateral Decubitus Positions

This is a prospective, single-center, crossover study comparing EndoFLIP measurements obtained in two patient positions, supine and left lateral decubitus, in pediatric and young adult patients. The Endoluminal Functional Lumen Imaging Probe (EndoFLIP) is an FDA-approved device for patients aged 5 and older that utilizes high-resolution impedance planimetry and volume-controlled …

5 - 21 years of age All Phase N/A
d dezhi zhang

The Diagnostic Value of Subharmonic Imaging Technology Combined With Liver Stiffness and Platelet Count for High-risk Esophageal and Gastric Varices in Patients With Liver Cirrhosis

To evaluate the diagnostic value of the combined model of subharmonic-assisted pressure estimation (SHAPE), liver stiffness (LSM), and platelet count (PLT) for high-risk esophageal and gastric varices (HRV)

18 years of age All Phase N/A
H Hong-Gang Duan, doctor

Diagnosis and Treatment of Foreign Bodies Outside Pharynx and Esophagus Lumen

Objective: To improve the success rate of the treatment of migrating foreign bodies in the upper aerodigestive tract. Methods: The medical records of inpatients conforming to the diagnosis of migrating foreign bodies between 2020 and 2025 were reviewed. Data regarding age, gender, time from onset to hospitalization, computed tomography (CT) …

18 - 70 years of age All Phase N/A
S Sara Nordio, PhD

Clinical and Instrumental Assessment Tools for Neurogenic Dysphagia: Translation and Validation

This study aims to translate and validate Italian versions of several clinical assessment tools for patients with neurogenic dysphagia. The instruments include: The New Zealand Secretion Severity Scale, which evaluates secretion management; The Reflex Cough Test from the I\&I cranial nerves assessment; The VASES scale used during fiberoptic endoscopic evaluation …

18 - 85 years of age All Phase N/A
M Ming-Yen Hsiao

Effect of Direct Chin-tuck Against Resistance on Swallowing Function

Chin-tuck Against Resistance (CTAR) is a widely used training method in swallowing rehabilitation that strengthens the suprahyoid muscles, enhancing their contraction during swallowing and promoting the anterior-superior movement of the hyoid-larynx complex, thus improving the swallowing process. In 2022, Dr. Meng et al. discovered that for a patient with ineffective …

18 - 90 years of age All Phase N/A

External Pharyngeal Exerciser and Dysphagia

The goal of this a clinical trial is to test the effect of a pharyngeal exerciser in rehabilitation of pharyngeal phase of swallowing in patients with dysphagia. The main question it aims to answer is: •Does application of pharyngeal exerciser improve swallowing as evidenced by need for prescribed intervention for …

18 years of age All Phase N/A
M Mark Kern

External Pharyngeal Exerciser and Pharyngeal Phase of Swallowing

This study of healthy young and elderly individuals is intended to assess the effects of pharyngeal exerciser on pharyngeal pressure phenomenon during swallowing. Our specific aim is to test if the pharyngeal exerciser increases the workload of muscles involved in pharyngeal phase of swallowing.

18 - 85 years of age All Phase N/A
J Jacopo Galli

Tracheal Tube and Swallowing After Head and Neck Surgery

The present study was designed as a cross-sectional observational study providing the enrollment of tracheostomized patients undergoing major oncological surgery for head-neck cancer. Aims to provide objective data on the bolus transit during swallowing in tracheostomized patients with tracheal tube and without tracheal tube closing directly the tracheal stoma with …

18 - 70 years of age All Phase N/A
D Daniel R Duncan, MD, MPH

Effect of Thickened Feeds on Clinical Outcomes in Children With Brief Resolved Unexplained Event

This observational study will examine the effects of thickened feeds on clinical outcomes and healthcare utilization in infants with brief resolved unexplained event (BRUE).

- 12 years of age All Phase N/A

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