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Surgery Clinical Trials

A listing of Surgery medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 2,473 clinical trials
I Ianis Siriopol

TIVA Versus Balanced Anesthesia on Muscle Mass in CRC Surgery

This study is aimed at clarifying changes in body composition during the perioperative period and identifying risk factors for skeletal muscle mass loss in patients with colorectal cancer. The investigators will asess the impact of the type of anaesthesia (total intravenous anaesthesia/sevoflurane anaesthesia) for colorectal surgery on the muscle function …

18 years of age All Phase N/A
D Didem Bozak

Popliteal Nerve Block for Acute Achilles Tendon Rupture Repair Surgery

Achilles tendon rupture is common, yet the value of popliteal nerve block for postoperative pain control during surgical repair remains uncertain. Despite widespread use, evidence supporting its analgesic effectiveness is limited, and both popliteal nerve block and Achilles tendon repair carry risks of nerve injury. This randomized, placebo-controlled trial will …

18 - 65 years of age All Phase N/A
N Neil Reddy, BS

Pelashield™ PainGuard™ vs Restrata® in HS Surgery

Hidradenitis Suppurativa (HS) is a long-lasting skin condition that causes painful lumps and infections. In severe cases, patients need surgery to remove the affected skin. After surgery, a wound dressing called a wound matrix is placed over the area to help the skin heal. This study will compare two different …

18 years of age All Phase N/A
J Jung-Bin Park, M.D.

Cardiac Index-Guided Intraoperative Hemodynamic Management in Pediatric Moyamoya Surgery

This prospective randomized controlled trial evaluates whether individualized cardiac index-guided intraoperative hemodynamic management reduces postoperative transient ischemic episodes in pediatric patients undergoing encephaloduroarteriosynangiosis (EDAS) for Moyamoya disease. Patients are randomized 1:1 to goal-directed fluid therapy based on baseline cardiac index versus standard arterial pressure-based management. The primary outcome is the …

1 - 18 years of age All Phase N/A
M Manuel A Guerrero Gutierrez, MD

Indocyanine Green Fluorescence Angiography (ICG-FA) in Revisional Bariatric Surgery

This study will compare different doses of a green fluorescent product that is administered during weight loss surgery in order to observe where blood vessels are located. There is uncertainty around the optimal dose of this product for patients with obesity, so this study will aim to study if the …

18 years of age All Phase N/A
I Iris Tang

Personalised Timing of Interval Debulking Surgery in Advanced Ovarian Cancer

About 70% of epithelial ovarian cancer patients are diagnosed at advanced stage. When primary optimal surgery is not possible, neoadjuvant chemotherapy will followed by interval debulking surgery is one treatment option. However, there is no consensus on the optimal timing of the surgery. CA125 is a well-known tumor marker in …

18 years of age Female Phase 2
B Bora Bilal

Serratus Posterior Superior Intercostal Plane Block for Arthroscopic Shoulder Surgery

Postoperative pain is a significant problem in patients undergoing arthroscopic shoulder surgery. This situation disrupts the patient's comfort and affects the functional outcome after surgery by preventing early rehabilitation. Various methods are used for postoperative pain control. Intravenous opioid agents are one of the most commonly used analgesic techniques. However, …

18 - 75 years of age All Phase N/A
N Nicole Collaco

Feasibility Trial of ScarWork for Post-breast Surgery Pain Syndrome.

Breast cancer is the most common cancer in women in the United Kingdom (UK). Most women are treated with a combination of surgery and radiotherapy. While these treatments are effective, they can cause ongoing breast pain for some, which can last months or even years. This long-term pain can have …

18 years of age All Phase N/A
I Iris Tang

Personalized Timing of Interval Debulking Surgery in Advanced Ovarian Cancer

About 70% of epithelial ovarian cancer patients are diagnosed at advanced stage. When primary optimal surgery is not possible, neoadjuvant chemotherapy will followed by interval debulking surgery is one treatment option. However, there is no consensus on the optimal timing of the surgery. CA125 is a well-known tumor marker in …

18 years of age Female Phase 2

Bariatric Surgery Evaluation and Assessment of Treatment Efficacy - Intervention Trial

The goal of this clinical trial is to evaluate if a bariatric surgery strategy will improve clinical endpoints, cardiac parameters and functional status in patients with obesity (with BMI 32-40 kg/m2) and symptomatic HF with preserved or mildly reduced LVEF in combination with AF, as compared to standard of care. …

45 - 70 years of age All Phase N/A

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