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Surgery Clinical Trials

A listing of Surgery medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 2,630 clinical trials
D David MOSZKOWICZ

Surgery with Botulinum Toxin a for Incisional Hernia

After laparotomy, treating large incisional hernias (width >= 10cm) proves challenging due to the progressive retraction of lateral abdominal muscles and the separation of rectus muscles. This width is a significant risk factor for repair failure and recurrence. High rates of severe postoperative morbidity, up to 50%, are reported, linked …

18 - 79 years of age All Phase 3
M Malgorzata Domagalska, Ph.D.

Erector Spinae Plane Block for Cervical Spine Surgery

The study aims to assess the interfacial plane blocks' effect on pain level, course of postoperative rehabilitation, and anti-inflammatory analgesic effect.

18 - 100 years of age All Phase 4
V VIRGINIA VARGIU

No-Stoma Policy in Advanced Ovarian Cancer Surgery

Resection of the sigmoid-rectum is a procedure frequently required in cytoreductive surgery for advanced ovarian cancer, and it is also among the procedures with the highest risk of complications. One of the major, albeit uncommon, complications of intestinal anastomosis is anastomotic leakage. According to the literature, the rate of anastomotic …

18 years of age Female Phase N/A
B Bruna Maccaferri, MD

Spine Surgery for Lenke 1 Adolescent Idiopathic Scoliosis

Idiopathic scoliosis of developmental age (AIS) is the most vertebral deformity in the adolescent population, with a prevalence of 1-3%. The treatment of AIS depends on the morphology and extent of the curve and the growth potential residual, can range from simple clinical-radiological monitoring, to the use of braces to, …

12 - 21 years of age All Phase N/A
M Merve Gaye Akgok, PhD Student

Hilotherapy vs. Kinesio Taping in Orthognathic Surgery Recovery

This prospective randomized controlled trial aims to compare the effects of kinesio taping and hilotherapy on postoperative edema, pain, and trismus in patients undergoing bimaxillary orthognathic surgery.

18 - 50 years of age All Phase N/A
A Alperen Can K Kökten

Surgeon-Guided Serratus Block in Breast Reduction Surgery

Surgeon guided serratus block, which can be performed by the surgeon in participants undergoing breast reduction surgery, may reduce the sensation of pain from the surgical field in the postoperative period. Thus, participants experience less pain in the postoperative period, consume less analgesics, and there is a decrease in related …

18 - 65 years of age Female Phase N/A
A Alexander T Yahanda, MD, MPHS

Auricular Vagal Nerve Stimulation for Spinal Fusion Surgery

This study is a randomized controlled trial that will evaluate the effect of non-invasive auricular vagal nerve stimulation on inflammatory markers, glycemic control, postoperative pain, and inflammation-related clinical outcomes after long-segment spinal fusion surgeries when compared to current accepted management.

18 years of age All Phase N/A
C Cancer Connect

Testing the Addition of an Immunotherapy Drug, Cemiplimab (REGN2810), Plus Surgery to the Usual Surgery Alone for Treating Advanced Skin Cancer

This phase III trial compares the effect of adding cemiplimab to standard therapy (surgery with or without radiation) versus standard therapy alone in treating patients with stage III/IV squamous cell skin cancer that is able to be removed by surgery (resectable) and that may have come back after a period …

18 years of age All Phase 3
D David Kent, MSc

Home-based Exercise for Frail Individuals Prior to Cardiac Surgery

The goal of this quasi-experimental feasibility study is to determine if a home based exercise program, that is supported virtually by a physiotherapist, is feasible for frail adults that are waiting for cardiac surgery. The main questions it aims to answer are: Will patients be interested in participating in a …

18 years of age All Phase N/A
M Min Yan

Perioperative Blood Conservation: Role of Combined Iron Supplementation Protocols in Reducing Allogeneic Transfusion

The goal of this clinical trial is to learn if a combined iron supplementation regimen can reduce the need for blood transfusions in adults with iron-deficiency anemia undergoing major elective cardiac surgery. The trial will also look at whether this regimen is safe and well tolerated. The main questions it …

18 - 85 years of age All Phase N/A

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