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Surgery Clinical Trials

A listing of Surgery medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 2,614 clinical trials
X Xiaojing Shi, PhD

ITGA6 Targeting NIR-II Fluorescence Image Guided Surgery

In this study, the investigators will detect hepatocellular carcinoma lesions using fluoescence imaging with ITGA6 targeting probes during tumor resection surgery. The aim is to evaluate wether intraoperative fluorescence imaging targeting ITGA6 can help to improve the detction effect of hepatocellular carcinoma, and finally help the accurate surgical resection. The …

18 - 80 years of age All Phase 1
M Mohamed M Elshamaa, Lecturer

Single-step Functional Sinus Endoscopy and Transoral Surgery

Dento- alveolar or dental structural diseases that affect the floor of the maxillary sinus can cause maxillary sinusitis which is known as odontogenic maxillary sinusitis (OMS). Many treatment protocols have been documented to treat OMS. However, There is no unanimity among clinicians on how and who should treat OMS, whether …

18 years of age All Phase N/A

Evaluation of IRDye800CW-nimotuzumab in Lung Cancer Surgery

The purpose of this study is to determine the safety, optimal dose and imaging time of the investigational product, IRDye800CW-nimotuzumab for use as a near infrared imaging probe for image-guided surgery during lung cancer resection. IRDye800CW-nimotuzumab targets cancer cells over-expressing EGFR, allowing tumors to be visualized and may help surgeons …

18 - 80 years of age All Phase 1/2
P Philippe PR Richebé, MD, PhD

Thoracic Paravertebral Block Anesthesia for Breast Cancer Surgery

Background Mastectomies are traditionally performed under general anesthesia (GA), often with the addition of regional anesthesia for post-operative pain relief. Thoracic paravertebral blocks (TPVB) had previously been described in the literature to be sufficient for intra-operative anesthesia as an alternative to GA. A 2021 literature review by Cochrane Library comparing …

18 years of age Female Phase N/A

Effects of Prone Position After Major Abdominal Surgery

Evaluation of postoperative prone position after major abdominal surgery. A randomized clinical trial of 100+100 patients and further add a voice/speech/singing protocol.

years of age All Phase N/A

dENdritic Cell Therapy Combined With SURgEry in Mesothelioma

The ENSURE trial is an open label, single center, phase 1, feasibility study. Sixteen adult patients diagnosed with resectable epithelioid malignant pleural mesothelioma (MPM) will be enrolled following first-line chemotherapy. Before standard-of-care chemotherapy, a leukapheresis will be performed and monocytes will be used for differentiation to dendritic cells (DCs) using …

18 years of age All Phase 1
J Juan Fiorda, MD

Effect of TEAS on PONV After Spinal Surgery

The proposed research will utilize electroacupuncture, a type of needleless acupuncture that uses electrostimulation, in a randomized, double blind study, to evaluate the incidence of post-operative nausea and vomiting (PONV) in patients undergoing spinal surgeries with the transcutaneous electrical acupoint stimulation (TEAS) compared to patients without TEAS.

18 years of age All Phase N/A
V Vanessa SALIOU

Virtual Reality in Awake Surgery : Pilot Study VIRAS

The virtual reality mask is a tool likely to improve the conditions for performing awake surgery by improving tolerance for the patient, by improving ergonomics in the operating room. In order to control the risks as well as possible, the investigators propose to test the equipment on patients who will …

18 - 75 years of age All Phase N/A
V Vilma Rosario

Surgery and Heated Intraperitoneal Chemotherapy for Adrenocortical Carcinoma

Objectives To determine intraperitoneal (IP) progression free survival after optimal debulking and heated intraperitoneal chemotherapy (HIPEC) with cisplatin in patients with IP spread of adrenocortical cancer. Determine morbidity of this procedure in this patient population. Determine the impact of surgery and HIPEC on quality of life (QOL) and hormone excess. …

18 - 99 years of age All Phase 2

Adult Spinal Deformity Surgery Real-World Functional Activity

The purpose of this study is to measure functional activity and stability in spinal deformity patients utilizing motion analysis testing and accelerometers.

18 years of age All Phase N/A

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