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Surgery Clinical Trials

A listing of Surgery medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 2,630 clinical trials

Tranexamic Acid in Adult Spinal Deformity Surgery

Posterior spinal surgery for adult deformity is associated with high incidence of blood loss and need for blood transfusion and intraoperative blood salvage, with associated increased cost and risk for perioperative complications. Tranexamic acid (TXA) is relatively inexpensive anti-fibrinolytic agent that has been proven effective for decreasing intraoperative blood loss …

18 - 80 years of age All Phase 3
C Chris Peach, MBBS FRCS (Tr&Orth) MD

Shoulder Surgery Traditional vs Accelerated Rehabilitation Trial

This is a randomised controlled trial involving patients who have a double-row arthroscopic rotator cuff repair. Null hypothesis: There is no difference in outcome between standard rehabilitation and accelerated rehabilitation after arthroscopic rotator cuff repair. Following surgery, they will be randomised to one of two groups: Standard rehabilitation, with enforced …

40 - 80 years of age All Phase N/A
l lukas gasteiger

High Intensity PreHab Before Major Abdominal Surgery

The risk for major cardiac cardiovascular events (MACE) within the first 30 day after surgery is nit only associated to the patient relate risk factors but also to the kind of surgery. Surgical interventions can be distinguished infield risk (MACE <1%), moderate risk (MACE 1-5%) and high risk (MACE > …

18 - 99 years of age All Phase N/A
S Sue Hyun Kim, MD

Early RRT in AKI After Cardiac Surgery

Acute kidney injury (AKI) is one of the major complications after cardiac surgery that may affects 20% to 40% of patients according to the definitions. Also, AKI after cardiac surgery is associated with high morbidity and mortality, with eight-fold increase in the odds ratio of death when renal replacement therapy …

19 years of age All Phase N/A
K Koivurova

Robotic Versus Laparoscopic Surgery for Deep Endometriosis

The objective of this study is to examine whether robot-assisted laparoscopy is superior compared to conventional laparoscopy as regards to patient outcome.

18 - 50 years of age Female Phase N/A
M Mohamed F Salman, MD

Efficacy of Fibrin Sealant in Hypospadias Surgery

The aim of the study was to evaluate if application of a fibrin sealant over the urethroplasty suture line for waterproofing instead of a dartos vascularized pedicled flap to reduce complications and improve the outcome in hypospadias repair.

3 - 18 years of age Male Phase N/A
P Pim van Leeuwen, MD/PhD

Tracer-Guided Surgery for Recurrent Prostate Cancer

ADT with or without robot-assisted PSMA-radioguided surgery for patients with recurrent prostate cancer.

18 years of age Male Phase 2
Y Yin Li, MD

Surgery or Chemoradiotherapy for Cervical Esophageal Cancer

To compare surgery with definitive chemoradiotherapy for patients with resectable cervical esophageal squamous cell carcinoma.

18 - 75 years of age All Phase N/A
P Philippe PR Richebé, MD, PhD

Neurocognitive Disorders After Major Surgery in Elderly

The objective of the study is to investigate, in patients aged 70 years and over undergoing major non-cardiac surgery, the effect of electroencephalic (EEG)-guided anesthesia on postoperative neurocognitive disorders when controlling for intraoperative nociception, personalized blood pressure targets and using full information provided by the processed EEG monitor (including burst …

70 years of age All Phase N/A
F Fredrik Schiöler, MD

Fluid Challenge and Plasma Volume, During Surgery

A short bolus infusion of fluid, called "fluid challenge" is commonly recommended for fluid treatment during longer surgery. However a prolonged increase of the blood volume is a prerequisite to recommend the technique. The purpose with the study is to examine the plasma expanding effect of three different fluid challenge …

18 - 80 years of age All Phase 4

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