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Surgery Clinical Trials

A listing of Surgery medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 2,614 clinical trials
F Feng Duan, MD

TACE Combined Surgery for the Resectable Huge HCC

Huge hepatocellular carcinoma (HCC) is defined as a tumor with a maximum diameter greater than 10 cm. With advancements in surgical techniques, hepatectomy can be performed safely in some patients with huge HCC without vascular invasion or distant metastasis and with preserved liver function. The high risk of recurrence after …

18 - 75 years of age All Phase N/A
L Lytfi Krasniqi, MD

Inflammation and Postoperative Atrial Fibrillation in Cardiac Surgery

Postoperative atrial fibrillation (POAF) is a common complication after cardiac surgery, marked by an irregular and rapid heart rate, and associated with increased morbidity, longer hospital stays, and higher costs. Its complex pathophysiology involves atrial remodeling, inflammation, and autonomic dysregulation. Surgical trauma and cardiopulmonary bypass trigger an inflammatory response, releasing …

18 - 99 years of age All Phase N/A
L Letizia Castelli, PhD

Balance in the Strabismic Patient Undergoing Strabismus Surgery

Strabismus is a clinical condition characterized by the failure of the visual axes of the two eyes to align on the stared object. There are many possible causes of strabismus, but it can be divided into two main groups: concomitant strabismus, which is characterized by an almost equal angle of …

16 - 65 years of age All Phase N/A
N Nicolas Bertrand, MD

Non-invasive Blood Pressure Monitoring in Carotid Surgery

Carotid endarterectomy surgery carries significant neurological and cardiac risks, requiring continuous monitoring of blood pressure. In standard practice, this monitoring is carried out using an arterial catheter inserted at the start of the operation. This invasive procedure is generally not well received by the patient and is a source of …

18 years of age All Phase N/A
E Eda Caferoglu, Dr

Sarcopenia and Neuromuscular Block in Gastrointestinal Cancer Surgery

This prospective observational study aims to evaluate the effects of sarcopenia on intraoperative neuromuscular block (NMB) in patients undergoing gastrointestinal cancer surgery. Adult patients scheduled for elective gastrointestinal cancer surgery will be grouped as sarcopenic or non-sarcopenic based on preoperative abdominal CT scans. Neuromuscular block parameters, including onset time, depth, …

18 - 75 years of age All Phase N/A

Longitudinal Assessment of Biomarkers After Oesophagogastric Cancer Surgery

Oesophagogastric cancer (cancer of the gullet and stomach) is the fifth most common cancer in England and Wales with 16,000 new cases diagnosed every year. Survival rates are poor with only 15% surviving beyond 5 years. There is also increasing research to understand the cancer biology and factors allowing cancers …

18 - 90 years of age All Phase N/A
B Bahira Shahim, MD, PhD

Ventricular Arrhythmias in Patients Undergoing Mitral Valve Surgery

Study objectives: To assess the impact of mitral valve surgery for mitral regurgitation on ventricular arrhythmic burden and surrogate markers of fibrosis in patients with arrhytmogenic mitral valve prolapse (MVP) from baseline to 6 months after surgery To characterize the molecular landscape of arrhytmogenic MVP Study design: -Prospective explorative observational …

18 years of age All Phase N/A
S Susanne Leij

QoL in OSA patiënts Treated With MMA Surgery.

The aim of this observational study is to evaluate the impact of maxillomandibular advancement surgery on the quality of life in patients treated with obstructive sleep apnea. The main question it aims to answer is: Does MMA surgery in OSA patiënts improve their quality of life? Patients will answer online …

18 years of age All Phase N/A
G Gianluca Costa, MD, PhD

Gastrointestinal Emergency Surgery: Evaluation of Morbidity and Mortality

Gastrointestinal Emergency Surgery: Evaluation of Morbidity and Mortality

18 years of age All Phase N/A
P Pa Thor, PhD

Lumoptik BRIGHTPOINT Reflectometer Device for Lumbar Epidural Placement

The goal of this clinical trial is to test the BrightPoint Epidural device as the first system to use multispectral reflectometry to find the epidural space in lumbar neuraxial procedures requiring epidural needle. The main questions it aims to answer are: Is the device a qualitatively effective secondary confirmation of …

18 - 99 years of age All Phase N/A

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