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Surgery Clinical Trials

A listing of Surgery medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 2,670 clinical trials
M Meng

GLP-1 Therapy After Bariatric Surgery in Chinese Patients With Obesity

Obese patients exhibit considerable heterogeneity and complex comorbidities, making long-term effective management challenging with monotherapy. While bariatric surgery remains the most effective weight-loss intervention, postoperative weight regain and metabolic deterioration remain significant concerns. glucagon-like peptide-1 receptor agonists (GLP-1RA) offer distinct advantages for weight loss and metabolic control, and their combination …

18 - 60 years of age All Phase N/A
S Selen Topalel, MD

Multimodal Fascial Plane Block for Postoperative Analgesia in Isolated CABG Surgery

Postoperative pain following coronary artery bypass grafting (CABG) via median sternotomy remains a significant clinical problem and is associated with increased opioid consumption and postoperative complications. Fascial plane blocks have emerged as part of multimodal analgesia strategies in cardiac surgery. This prospective, randomized, controlled, single-blinded study aims to evaluate the …

18 - 80 years of age All Phase N/A
A Atakan Sezgi, M.D.

Flow-Controlled Versus Volume-Controlled Ventilation in Lumbar Disc Herniation Surgery

This prospective randomized trial aims to compare the effects of flow-controlled ventilation (FCV) and volume-controlled ventilation (VCV) on intraoperative airway pressures and oxygenation in patients undergoing lumbar disc herniation surgery under general anesthesia. Adult patients aged 18-65 years, with ASA physical status I-III and a body mass index of 18-30 …

18 - 65 years of age All Phase N/A
M Mahmoud El Azhary, Lecturer

Impact of Bariatric Surgery on Female Sexual Function and Sex Hormones

The goal of this observational study is to learn about how weight loss surgery (also called bariatric surgery) affects sexual function and sex hormone levels in women with severe obesity. It will also look at how the surgery affects mood, quality of life, body image, and the partner's sexual health. …

18 - 45 years of age Female Phase N/A
F Fatma Acil, M.D.

Serratus Posterior Superior Intercostal Plane Block in Minimally Invasive Cardiac Surgery

This randomized, double-blind, placebo-controlled study aims to evaluate the effect of the serratus posterior superior intercostal plane (SPSIP) block on postoperative pain and opioid consumption in patients undergoing minimally invasive cardiac valve surgery via mini-thoracotomy.

18 - 75 years of age All Phase N/A
R Romual Mentaverri, Pr

Use of Discarded Surgery Human Tissue Specimens for Basic Science Research

Although it is now established that calcification process result from the joint and coordinated action of different cell types, many areas of shadow remain regarding the spatio-temporal implementation of these events. Highlighting these processes requires additional research to consider new approaches to clinical management of patients with such conditions. It …

18 years of age All Phase N/A
D Dana Kosh, Dr.

Nociception Level Index After Brachial Plexus Block In Upper Extremity Surgery

The present prospective within-subject observational study will evaluate whether unilateral brachial plexus block (BPB) induces measurable lateralized autonomic modulation, assesses using bilateral Nociception Level (NoL) monitoring during standardized intraoperative stimuli under general anesthesia. Regional anesthesia efficacy is traditionally assessed through sensory and motor examination. However, objective physiologic markers reflecting sympathetic …

18 years of age All Phase N/A
D Dijana Filipović, MSc

Early Postoperative Physiotherapy to Prevent Respiratory Insufficiency After Elective Heart Surgery

This study aims to determine whether starting respiratory physiotherapy one hour after removal of the breathing tube following elective coronary artery bypass graft (CABG) surgery leads to better recovery than the current standard approach, in which physiotherapy begins on the first postoperative day. The study will evaluate whether earlier physiotherapy …

18 - 80 years of age All Phase N/A
A Ahmed Elsaeed Habib

Lateral Crural Steal With Columellar Strut Graft in Primary Open Rhinoplasty

The goal of this clinical trial is to assess the effect of Lateral crural steal with Columellar strut graft done in Primary Open Rhinoplasty and its long-term sustainability on nasal tip projection and nasal tip rotation.

18 - 60 years of age All Phase N/A
R Rebecca Schneyer, MD

Short Title: Standard vs. Lower Pressure Pneumoperitoneum

This study aims to investigate the effect of varying insufflation pressures on post-operative pain and adequacy of surgical field visualization among patients undergoing laparoscopic surgery with a minimally invasive gynecologic surgeon.

18 years of age Female Phase N/A

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