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Surgery Clinical Trials

A listing of Surgery medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 2,628 clinical trials
D Doncaster Royal Infirmary

Assessing Frailty and Its Impacts on Patients Facing Major GI Surgery

The study team will look at 3 new tests that will make it easier to measure frailty in patients awaiting surgery for cancer and compare them against standard clinical measures of frailty in a pilot study. The expected outcome is that evidence will be collated in order to apply for …

18 years of age All Phase N/A
R Rongchong Huang, M.D.

Effect of Bariatric Surgery on Cardiac Function in Patients With Hypertension

The purpose of this study is to investigate the effect of bariatric surgery on cardiac function assessed by echocardiography in patients with hypertension.

17 - 70 years of age All Phase N/A
G Guangyou Duan, MD

The Effect of Coenzyme Q10 in Preventing Pain After Thoracoscopic Surgery

This study aimed to assess the effectiveness of Coenzyme Q10 in preventing both acute and chronic pain following thoracoscopic surgery, with a focus on its potential benefits in reducing the incidence and severity of pain.

18 - 75 years of age All Phase 4
H Hülya Tosun Söner, doctor

Monitoring Changes in Endotracheal Tube Cuff Pressure During Laparoscopic Bariatric Surgery

This prospective observational cohort study was designed to assess the relationship between ETT cuff pressures and airway pressures in obese patients undergoing laparoscopic bariatric surgery. We hypothesized that the ETT cuff pressures will rise in direct relationship to increases in the peak and mean airway pressures.

18 - 70 years of age All Phase N/A
C Christophe Beyls, MD

Hydrocortisone Plus Fludrocortisone in High-risk Patients Undergoing for Cardiac Surgery

Cardiac surgery is a high-risk surgery and is associated with a rate of postoperative adverse outcomes. Like many others major surgery, cardiac surgery procedures induce a proinflammatory phase usually counterbalanced with an immunosuppressive phase so the immune response remained balanced. In some cases, the immune response might be dysregulated with …

18 years of age All Phase 3
J Jülide Ergil, Professor

Flow-Controlled Versus Volume-Controlled Ventilation in Lumbar Disc Herniation Surgery

This prospective randomized trial aims to compare the effects of flow-controlled ventilation (FCV) and volume-controlled ventilation (VCV) on intraoperative airway pressures and oxygenation in patients undergoing lumbar disc herniation surgery under general anesthesia. Adult patients aged 18-65 years, with ASA physical status I-III and a body mass index of 18-30 …

18 - 65 years of age All Phase N/A
F Fatma Acil, M.D.

Serratus Posterior Superior Intercostal Plane Block in Minimally Invasive Cardiac Surgery

This randomized, double-blind, placebo-controlled study aims to evaluate the effect of the serratus posterior superior intercostal plane (SPSIP) block on postoperative pain and opioid consumption in patients undergoing minimally invasive cardiac valve surgery via mini-thoracotomy.

18 - 75 years of age All Phase N/A
E Engin Çetin, M.D

Serratus vs ESP Block for Postoperative Pain in Unilateral Breast Surgery

This prospective, randomized, assessor-blinded trial compares serratus posterior superior intercostal plane block (SPSIPB) and erector spinae plane block (ESPB) for postoperative analgesia in unilateral breast surgery. 54 patients will be randomized to receive either SPSIPB or ESPB before general anesthesia. The primary outcome is postoperative pain scores within the first …

18 - 65 years of age Female Phase N/A
M Meng

GLP-1 Therapy After Bariatric Surgery in Chinese Patients With Obesity

Obese patients exhibit considerable heterogeneity and complex comorbidities, making long-term effective management challenging with monotherapy. While bariatric surgery remains the most effective weight-loss intervention, postoperative weight regain and metabolic deterioration remain significant concerns. glucagon-like peptide-1 receptor agonists (GLP-1RA) offer distinct advantages for weight loss and metabolic control, and their combination …

18 - 60 years of age All Phase N/A
M Michael Grach, Dr.

Nociception Level Index After Brachial Plexus Block In Upper Extremity Surgery

The present prospective within-subject observational study will evaluate whether unilateral brachial plexus block (BPB) induces measurable lateralized autonomic modulation, assesses using bilateral Nociception Level (NoL) monitoring during standardized intraoperative stimuli under general anesthesia. Regional anesthesia efficacy is traditionally assessed through sensory and motor examination. However, objective physiologic markers reflecting sympathetic …

18 years of age All Phase N/A

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