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Surgery Clinical Trials

A listing of Surgery medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 2,670 clinical trials
M Marco Noventa, MD

ULTRA-LAP Trial: Laparoscopic Debulking Surgery (LDS) in Advanced Ovarian Cancer

ULTRA-LAP is a prospective study is to investigate the safety, efficacy and feasibility of laparoscopic debulking surgery (LDS) for the treatment of patients with advanced ovarian cancer. The outcomes to measure are: Safety: the rate of patients experiencing intra- and post-operative early and late morbidities (within the hospitalization and up …

18 years of age Female Phase N/A
L Lorenzo Cohen

Opioid-Sparing Effects of Nurse-Delivered Hypnosis During Breast Cancer Surgery

To hypnosedation alone given before and during surgery on reducing opioid use after surgery compared to standard general anesthesia given alone or with hypnosedation.

18 years of age All Phase 2/3
S Sarah Chouinard-Castonguay

Bone Health After Bariatric Surgery in Patients With Type 2 Diabetes

Background: Bone fragility is a complication of type 2 diabetes. Diabetes treatments may ameliorate or deteriorate bone fragility in this population. Bariatric surgery is gaining in popularity in people with type 2 diabetes and may impact bone health. Objectives: To evaluate the impact of the most popular bariatric procedure worldwide …

18 - 60 years of age All Phase N/A
J Juan Ibla, MD

Evaluation of Pro-Inflammatory Leukocyte Activity in Patients Undergoing Cardiac Surgery

The goal of this proposal is to prospectively collect data from a series of 200 patients (all ages) undergoing complex cardiac surgical procedures involving cardiopulmonary bypass (CPB) to: Measure the number of blood activated circulating monocytes before, during and after cardiac surgery and serum GABA and pro-inflammatory cytokine levels Understand …

years of age All Phase N/A
I Inés Ginot

Prophylactic Cholecystectomy in Midgut NETs Patients Who Require Primary Tumor Surgery.

The investigators want to study the effectiveness of prophylactic cholecystectomy in patients with midgut neuroendocrine tumor (jejunum, ileum or proximal colon) who require primary tumor surgery. When patients are diagnosed and are tributary to surgical treatment, the tumor might compromise vascularization, and patients need an extensive bowel resection. The patients …

18 years of age All Phase N/A
P Peter B Licht, MD, PhD

VATS Surgery Compared to Drainage in the Treatment of Pleural Empyema

Pleura empyema is a frequent disease with a high morbidity and a mortality rate of approximately 15%. Pleura empyema is characterized by the passage of three stages (I - III). The aim of treating the disease is to remove the infection and provide fully expansion of the lung. The initial …

18 years of age All Phase N/A
J Jacob Kinggaard Lilja-Fischer, MD

Surgery for Thyroid Cancer With or Without Autofluorescence to Prevent Hypoparathyroidism

The study aims to test if use of autofluorescence imaging (AF) reduces the risk of developing hypoparathyroidism (hypoPT) following surgery for thyroid cancer, either total thyroidectomy (TT) or completion hemithyroidectomy (cHT).

18 years of age All Phase N/A

ctDNA in CRC Patients Undergoing Curative-intent Surgery for Liver Metastases

This is a prospective multicenter cohort study, was designed to explore the prognostic value of ctDNA as a biomarker of disease response and recurrence or death in patients undergoing curative-intent surgical resection of Colorectal cancer liver metastasis.

18 years of age All Phase N/A
A Artem Gubko, Ph.D.

Antibacterial Tactics Based on Presepsin Level in Thoracic Aorta Surgery Patients

According to the literature, presepsin was recommended not only as an effective indicator in the diagnosis of sepsis in intensive care units, but also as a reliable prognostic marker of postoperative inflammatory processes in cardiac surgery. Previous study carried out in Petrovsky NRCS related to biomarkers in cardiac surgery and …

18 - 75 years of age All Phase N/A
M Martin Holmberg, MD

Spinal Morphine or Intravenous Lidocaine in Robot-assisted Upper Urologic Surgery

The goal of this clinical trial is to learn whether the addition of spinal analgesia leads to superior recovery in patients undergoing robotic-assisted laparoscopic upper urinary tract surgery under general anesthesia. The main questions it aims to answer are: Is the decrease in wellbeing as quantified by the patient-centered outcome …

18 years of age All Phase 3

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