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Surgery Clinical Trials

A listing of Surgery medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 2,670 clinical trials

Continuous ESP Block in Patients Undergoing CABG Surgery.

This study addresses articles and studies related to the erector spinae plane (ESP) block and its technique, advantages and disadvantages, applicability, among others. It aims to provide more information about this block, which is relatively new, and how it can be explored in the anesthesiologist's routine, mainly inserted in the …

years of age All Phase 3
A AHMET TAŞCI

Ureteral Access Sheaths in Endoscopic Kidney Stone Surgery

This prospective, randomized, comparative study aims to evaluate the impact of aspirating and non-aspirating ureteral access sheaths on success rates and complications in patients undergoing retrograde intrarenal surgery (RIRS) for kidney stones. A total of 70 patients with renal stones smaller than 2 cm will be enrolled and randomly assigned …

18 - 75 years of age All Phase N/A
M Mehmet Olcum, MD

Comparison of Endoscopic and Open Surgery for Gynecomastia

The goal of this observational study is to compare the clinical outcomes, safety, and patient satisfaction of endoscopic versus conventional open surgical techniques in adult male patients undergoing surgery for gynecomastia. The main questions it aims to answer are: Does endoscopic gynecomastia surgery provide better aesthetic outcomes and patient satisfaction …

18 - 60 years of age Male Phase N/A
A Asmaa S Farghaly, MD

Dose for Reversal of Heparin After Cardiopulmonary Bypass

Protamine sulfate is routinely used to reverse heparin anticoagulation after cardiopulmonary bypass (CPB). The conventional dosing strategy of 1 mg protamine per 100 IU of heparin may result in excess protamine exposure, which has been associated with anticoagulant effects, platelet dysfunction, and hemodynamic instability. Recent evidence suggests that lower protamine …

18 years of age All Phase N/A

Thoracic Paravertebral Block in Daytime Laparoscopic Partial Adrenalectomy

Day surgery refers to the entire diagnostic and therapeutic process completed within 24-48 h, including patient admission, surgery, and discharge. Research by Shariq et al suggested that daytime laparoscopic adrenalectomy was a safe and effective alternative to traditional inpatient treatment. Li et al demonstrated that daytime surgery for laparoscopic partial …

18 - 70 years of age All Phase N/A
G Gabriella Arlotta, MD

Blood Velocity Variation in Right Renal and Superior Mesenteric Arteries During Cardio-pulmonary Bypass

The cardiopulmonary by-pass technique, used in cardiac surgery to obtain a bloodless operating field and an immobile heart, determines important effects on the blood vessel wall, especially when a continuous and non-continuous blood flow is used. In fact, a reduction in Nitric Oxide (NO) production by the endothelium, an increase …

18 years of age All Phase N/A
P Pa Thor, PhD

Lumoptik BRIGHTPOINT Reflectometer Device for Lumbar Epidural Placement

The goal of this clinical trial is to test the BrightPoint Epidural device as the first system to use multispectral reflectometry to find the epidural space in lumbar neuraxial procedures requiring epidural needle. The main questions it aims to answer are: Is the device a qualitatively effective secondary confirmation of …

18 - 99 years of age All Phase N/A

The Effect of Different Flap Closure Techniques on Postoperative Morbidity in Impacted Third Molar Surgery

1\. ABSTRACT This study is a randomized controlled trial comparing the clinical efficacy and safety of four different flap closure techniques in reducing postoperative morbidity (pain, swelling, trismus, wound healing) and improving patient quality of life (GOHAI) following impacted mandibular third molar extraction. The methods include conventional suturing, sutureless technique, …

18 - 40 years of age All Phase N/A
J Jaclyn Himeles, MD

Topical 0.5% Timolol Solution for Healing Lower Extremity Wounds

Topical timolol, a β2-Adrenergic receptor (B2AR) antagonist, has demonstrated promise in wound healing over the past several years. The majority of the literature has evaluated the use of topical timolol to shorten wound healing time in chronic wounds of non-surgical etiologies. To date, there are no prospective randomized clinical trials …

18 years of age All Phase 1

Hydrocolloid Dressings for Oculofacial Plastic and Reconstructive Wound Healing

This study aims to explore the use of a hydrocolloid dressing (DuoDERM EXTRA THIN) as an alternative to the current standard of care. The dressing would be applied immediately after surgery and removed at a post-operative week 1 appointment. The dressing would eliminate the need for antibiotic ointment application and …

18 - 100 years of age All Phase N/A

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