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multiple-sclerosis Clinical Trials

A listing of multiple-sclerosis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 402 clinical trials
Y Yousri Benchaar

Investigating Eye-Movement Biomarkers of Disease Severity and Cognition in Multiple Sclerosis

The overarching goal of this research protocol is to acquire eye-tracking, cognitive, and disease-severity metrics in multiple sclerosis (MS) patients to further build up a database of MS patients and train a machine learning classifying algorithms to identify which eye-tracking metrics-or combination thereof-can serve as reliable markers of MS disease …

18 years of age All Phase N/A
R Rachael Coleman, MPH

Obesity and Pediatric Multiple Sclerosis

Obesity is one possible contributor to severity of multiple sclerosis and progression of the disease. We already know that obesity is a risk determinant for acquiring MS, yet the impact of obesity on pediatric MS disease expression and course is unknown. This study will evaluate the relationship between obesity, obesity-derived …

10 - 20 years of age All Phase N/A

Strategies for Adaptive Follow-up and Evaluation - Guiding Use of Indicators for De-Escalation in Multiple Sclerosis

The study will attempt to closely analyze Multiple Sclerosis (MS) patients after de-escalating or discontinuation of immunotherapy using clinical monitoring as well as digital and serological biomarkers in order to detect clinical progression or disease activity. As this is an observational study, it aims to closely follow-up on patients where …

18 years of age All Phase N/A
M Monica Grobberio

Supporting Mental Health in Daily Life After the Diagnosis of Multiple Sclerosis

The overall goal of this observational study is to learn about the psychological resources of mindfulness and flow experience available to persons newly diagnosed with multiple sclerosis (MS). The primary study aim will be to analyze the relation of flow and mindfulness with mental health among individuals who received an …

18 - 50 years of age All Phase N/A
A Athina Papadopoulou, PD Dr. med.

REtinal Markers In Neuroinflammatory Diseases ("REMIND")

The goal of this observational study, including patients with Multiple Sclerosis, patients with other neuroinflammatory diseases and healthy controls, is to determine the predictive value of retinal markers in predicting disease progression. Participants complete a questionnaire and undergo various non-invasive retinal routine clinical examinations.

18 years of age All Phase N/A
T Tammy Hoyt

ETNA-MS Device Validation Study

The overarching goal of this research protocol is to validate the effectiveness of Innodem's ETNA-MS device in informing clinicians on the disability status of Multiple Sclerosis (MS) patients. Effectiveness of the device will be assessed by the level of agreement between the EDSS estimated by the device and the actual …

18 years of age All Phase N/A

Assessment of the Quality of Life of Multiple Sclerosis Patients Treated With Ofatumumab in Real-life in France

SEPROS is a non-interventional study, based on primary data collection of MS adult patients who initiated ofatumumab as per neurologist practice and regardless of the study protocol.

18 - 99 years of age All Phase N/A
C Chiara Zecca, PD Dr. med.

Consolidation Therapy with Cladribine in Relapsing Multiple Sclerosis Patients

To investigate the impact on IgG and IgM concentration, infection risk and effectiveness of switching from anti-CD20 to cladribine compared to continued anti-CD20 treatment over 2 years in relapsing MS patients.

18 years of age All Phase N/A
B Beyza Özvar, MSc

Body Awareness, Trunk Stability, and Arm Function in MS

The aim of this study is to investigate the relationship between body awareness, trunk stabilization, and upper extremity functionality in patients with Multiple Sclerosis (MS). Hypotheses of the study: H1: There is a significant relationship between body awareness and upper extremity functionality in patients with MS. H2: There is a …

10 years of age All Phase N/A
B Beyza Özvar, MSc

Cut-Off Values for Gait and Balance in MS

Purpose of the Study: The aim of this study is to determine the cut-off values of gait variability and limits of stability-postural sways scores in patients with MS in order to identify fall risk at an early stage and take necessary precautions. Additionally, the study aims to compare the effectiveness …

18 years of age All Phase N/A

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