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chronic-obstructive-pulmonary-disease Clinical Trials

A listing of chronic-obstructive-pulmonary-disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 482 clinical trials
A Alexandra Arvaji

The Acute Cardiorespiratory Response to Blood-flow Restricted Versus Traditional Exercise Training Regimens (CaRe BFR)

The investigators hypothesize that BFR exercise regimens result in a different acute cardiorespiratory response pattern compared to traditional exercise regimens. Furthermore, the investigators hypothesize that these patterns differ between healthy participants and participants with COPD. Regarding secondary objective, the investigators hypothesize that BFR results in lower blood pressure responses compared …

18 - 90 years of age All Phase N/A
W Wytze de Boer, MD

Sonographic Diaphragm Function in AECOPD

The study will be conducted as a single-center, prospective cohort study. The primary objective of this study is to investigate the responsiveness of sonographic parameters of diaphragm to detect change in Borg score for dyspnea during hospitalisation for AECOPD without respiratory acidosis.

18 years of age All Phase N/A
J Jiayi Li

Heterogeneity of Lung Ventilation Determined by EIT During PFT in Patients With PRISM

To evaluate the demographic characteristics of PRISm population in patients with pulmonary function tests recommended by outpatient physicians. To investigate whether EIT can identify spatial and temporal heterogeneity of lung ventilation in individuals with PRISm during pulmonary function testing. To investigate the distribution patterns of lung ventilation in individuals with …

18 - 100 years of age All Phase N/A
K Karin Klooster, PhD

Bronchoscopic EmphysemA Treatment in THE NetherLands

Rationale: New bronchoscopic treatments for emphysema have shown promise in clinical trials, improving lung function, exercise capacity and possibly survival and are now being adopted by a number of centres in the Netherlands. It is important to ensure that the benefits seen in clinical trials are in fact reflected in …

years of age All Phase N/A
M Michele Vitacca, MD

Effect of Combined Endurance Training on ADL and Walking in COPD Patients

Chronic Obstructive Pulmonary Disease (COPD) is a chronic disease with related exercise intolerance and marked disability due to symptoms such as dyspnea and fatigue. Effort intolerance and exercise-induced symptoms cause marked impairment in completing activities of daily living (ADL). Pulmonary rehabilitation (PR), which has exercise as a major component, is …

years of age All Phase N/A
T Tristan Bonnevie

Predictive Properties of the 6-Minute Stepper Test for Mortality in COPD

Retrospective study aimed to answer the following research questions : What are the predictive properties of the 6-minute stepper in COPD for 2-year mortality in individuals with COPD ? What are the predictive properties of the 6-minute stepper in COPD for 5-year mortality in invididuals with COPD ?

18 years of age All Phase N/A
B Bryan A Ross, MD, FRCPC, MSc (Epi, Physiol)

Predicting Acute Exacerbations of COPD Using Wearable Devices and Remote Monitoring Technology With AI/ML Models

This study is aimed to collect real-time physiological data using two wearable devices (a biometric ring and a biometric wristband), daily lung mechanical measurements by a handheld oscillometer, and participant-reported symptoms in patients with COPD remotely from their home environment. The data will be used to train and validate artificial …

40 years of age All Phase N/A
B Buse Sarıkaya

Effect of Aronia Berry Consumption on Inflammatory Parameters

The study will aim to evaluate the effects of consuming freeze-dried aronia berries as an adjunct to medical treatment in patients with chronic obstructive pulmonary disease (COPD), focusing on anti-inflammatory, respiratory, and biochemical parameters. It will be conducted at a research hospital in Istanbul, involving 50 participants aged 50-80 diagnosed …

50 - 80 years of age All Phase N/A
a asia said Toukhy, head of clinical pharmacy

"The Effect of Inhaled Nitroglycerin for COPD Patients

this study aims to investigative the benefits of using nebulized nitroglycerin in improving respiratory functions in patients of late stage COPD

18 years of age All Phase 2/3

Mindful Steps 2.0: Promoting Physical Activity in Patients With COPD and HF

The goal of this fully-remote randomized controlled trial is to test the efficacy of Mindful Steps in facilitating physical activity compared to usual standard of care among 136 patients with COPD and/or HF. The main question it aims to answer is can this intervention promote physical activity as measured by …

40 years of age All Phase N/A

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