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mild-cognitive-impairment Clinical Trials

A listing of mild-cognitive-impairment medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 678 clinical trials
M Min Lou, PhD, MD

Oriental Intervention for Enhanced Neurocognitive Health (ORIENT) Diet in Patients With Intracranial / Carotid Stenosis

To test the effects of 6 month additional intervention of ORIENT diet versus usual medical treatment for Intracranial / Carotid Stenosis on cognitive decline, multi-mode MRI image markers and serum and fecal biomarkers in a randomized controlled trial of 120 patients with intracranial / carotid stenosis, who are aged older …

40 years of age All Phase N/A
N Nicolai Goettel, MD

Development of a Prediction Model for Delirium After Cardiac Surgery Using a Novel Self-Administered Preoperative Cognitive Assessment Tool

This observational cohort study is designed to validate the CogCheck application as a risk prediction tool for postoperative delirium in patients undergoing cardiac surgery.

60 years of age All Phase N/A
C Claudia Spies, MD, Prof.

Web-based Application to Test for Long-term Cognitive Deficits in BioCog Patients

In the present study, a long-term cognitive follow-up of participants of the BioCog cohort (data collection period 2014 - 2019, Ethical vote No: EA2/092/14) from the Berlin study center is to be will be performed in order to record long-term cognitive sequelae (7 to 10 years after study inclusion). In …

18 years of age All Phase N/A
N Nan Qiu, PhD

Neuromodulation and Attention Deficits in MDD

Multimodal study (Behavior, TMS, EEG) combining a sham-controlled intermittent theta burst stimulation (iTBS) intervention with an additional-singleton task and EEG to evaluate whether left dorsolateral prefrontal cortex (DLPFC) stimulation enhances cognitive control and modulates maladaptive attention processes in MDD and whether the effects are influenced by neuronavigated versus manual (Beam …

18 - 55 years of age All Phase N/A
B Barbara Plitnick, BSN

The Use of Rhythmic Light Therapy in Mild Cognitive Impairment

In this within-subjects, crossover study, participants will undergo Electroencephalogram (EEG) recordings before, during, and after each of three 1-hour sessions. All participants will experience all three conditions: (1) dual-frequency visual (10 and 40 Hz), (2) single-frequency visual (40 Hz), and (3) non-rhythmic stimulation. EEG spectral power and amplitude coupling will …

55 - 80 years of age All Phase N/A
R Researcher

Feasibility Study of 'SuperBrain BOOM' for Mild Cognitive Impairment Patients

The goal of this clinical trial is to learn whether a mobile-based personalized physical activity program called SuperBrain BOOM is safe and works to improve cognitive function, physical performance, mood, and quality of life in older adults (ages 50-85) with mild cognitive impairment (MCI). The main questions it aims to …

50 - 85 years of age All Phase N/A

Online Interplay Between Deciding and Acting With Mild Cognitive Impairment

The investigators aim to understand the interplay and neural structures involved with decision--making and movement for participants with mild cognitive impairment. Rapidly deciding and acting becomes bottlenecked with mild cognitive impairment and Alzheimer's, leading to detrimental outcomes such as falling and car crashes. The investigators work will have a tangible …

45 - 90 years of age All Phase N/A
V Victor DiRita, B.S.

Patient-Centered NeuroRehabilitation (PCN)

As individuals grow older, a number of factors can reduce our cognitive (or thinking) abilities such as "normal" aging, neurodegenerative diseases, and cardiovascular disease. This study will evaluate whether cognitive rehabilitation and transcranial electrical stimulation (TES) can improve cognitive abilities. Cognitive rehabilitation refers to methods that are used to improve …

50 years of age All Phase N/A
D Defei Chen

Biomarkers Related to PSCI: An fNIRS Study

This is an fNIRS study performed to identify biomarkers related to post-stroke cognitive impairment.

18 - 80 years of age All Phase N/A
C Celia DONG, PhD

The Impacts of Chronic Non-specific Low Back Pain on Cognitive Functions of Older Adults

Chronic non-specific low back pain (CNSLBP) is a prevalent condition among older adult and has been associated with an increased risk of executive function impairment. Studies have shown that older adults with chronic pain are more likely to show poor cognitive performance than healthy controls. Cognitive performance is particularly important …

60 - 85 years of age All Phase N/A

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