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nonalcoholic-steatohepatitis Clinical Trials

A listing of nonalcoholic-steatohepatitis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 156 clinical trials
L Luca Miele, MD, PhD

Optimizing Noninvasive assessMent Of DysmEtabolic Compensated Advanced Liver Disease

Non-alcoholic fatty liver disease (NAFLD) is responsible for a significant proportion of liver-related deaths and healthcare costs in the United States, accounting for approximately 36% of liver-related deaths and over one billion dollars in annual healthcare expenses. \[PMID: 34863359\] A recent analysis of healthcare costs in Italy showed that out …

18 years of age All Phase N/A
A Alok Bapatla, MD

Milk Thistle Clinical Trial in Pediatric NAFLD

Pediatric Fatty Liver disease is a growing problem in the United States and is expected to be the leading cause of Liver Transplantation in Adults in 20 years. Following lifestyle changes such as diet restrictions and exercise may be difficult to consistently maintain. The purpose of this study is to …

9 - 22 years of age All Phase 2
A Anastasia Teterina, PhD

Fatty Liver Patient Registry

The purpose of the Non-Alcoholic Fatty Liver Disease (NAFLD) registry is to collect demographic and clinical data on patients being treated for NAFLD and to determine the factors affecting the progression of the disease as well as the success of different treatment strategies.

18 years of age All Phase N/A

Fructose and Liver Diseases in Youth: Help Them FLY

Obesity has been increasing all over the world. This has lead to a significant increase of a liver disease in children called non-alcoholic fatty liver disease (NAFLD). NAFLD is a liver disease that ranges from excess fat being stored in the liver to an inflamed and fatty liver with fibrosis …

12 - 18 years of age All Phase N/A
R Rosemary Mullett

Investigating Pathological Mechanisms in Non-alcoholic Fatty Liver Disease

To identify key characteristics of the tissue resident and peripherally circulating immune-phenotype in addition to blood markers, metabolic profile, faecal and oral microbiota in non-alcoholic fatty liver disease

18 years of age All Phase N/A
G George Lau, MD

Nonalcoholic Steatohepatitis in Chinese Children

Nonalcoholic steatohepatitis (NASH) is now recognised as an increasing clinical problem in children. Steatosis without significant liver cell injury or fibrosis is the most common form of nonalcoholic fatty liver disease (NAFLD) in both adults and children. Studies in the adult population have variably suggested that steatosis is a benign …

1 - 18 years of age All Phase N/A
A Amira Mohamed, PhD

Role of Regulatory B Cells in the Pathogenesis of Metabolic Associated Fatty Liver Disease

To evaluate the role of regulatory B cells in the pathogenesis of metabolic associated fatty liver disease patients.

18 - 80 years of age All Phase N/A
A Allison Sullivan

Impact of Soymilk on Liver Disease Severity of Children With Non-alcoholic Fatty Liver Disease (NAFLD)

A randomized, controlled study of standard soy milk consumption compared to 2% fat cow's milk consumption in children with Non-alcoholic Fatty Liver Disease (NAFLD). The investigators hypothesize that the daily consumption of soy isoflavones found in the soy milk will be beneficial in reducing NAFLD and other obesity-related comorbidities. The …

5 - 12 years of age All Phase 2
F Florian Kiefer, MD, PhD

Cold-induced Brown Fat Activation and Hepatic Steatosis

In the recent years, research on brown adipose tissue (BAT) revealed that larger amounts as well as higher activity thereof are associated with a favourable metabolic phenotype. Longitudinal studies which applied recurrent cooling sessions demonstrated a high plasticity of BAT which significantly increased in size and activity during these studies. …

18 - 50 years of age All Phase N/A
S Steven Mathews, MD

Diet and Meal Timing in Patients With Metabolic Dysfunction Associated Steatoic Liver Disease

This study will assess the impact of time-restricted eating (8 hours of eating each day) with standard of care lifestyle recommendations (hypocaloric, Mediterranean diet and 30 minutes of exercise on at least 5 days/week) on the degree of fat in the liver as measured by magnetic resonance imaging.

18 - 65 years of age All Phase N/A

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