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nonalcoholic-steatohepatitis Clinical Trials

A listing of nonalcoholic-steatohepatitis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 164 clinical trials
F Ferial Elkalla, MD

Impact of NAFLD vs MAFLD Stigma on Quality of Life in Egyptian Patients

Non-alcoholic fatty liver disease (NAFLD) has become the leading cause of liver disease worldwide. The global burden of NAFLD is about 30% of the population, With a higher prevalence in Egypt about 47.5 %. The prevalence increases significantly with the presence of type 2 diabetes and obesity. NAFLD is commonly …

18 years of age All Phase N/A
L Luca Miele, MD, PhD

Secondary and Tertiary Digital Prevention of Non-alcoholic and Dysmetabolic Liver Disease

The prevalence of Metabolic dysfunction-associated steatotic liver disease (MASLD) and its severe form, Metabolic dysfunction-associated steatohepatitis (MASH), is high and they are increasingly becoming major causes of cirrhosis, hepatocellular carcinoma (HCC), and the need for liver transplantation. Due to the lack of noticeable symptoms during the early stages, the detection …

18 years of age All Phase N/A
J Johane P Allard, MD, FRCPC

Fatty Liver Patient Registry

The purpose of the Non-Alcoholic Fatty Liver Disease (NAFLD) registry is to collect demographic and clinical data on patients being treated for NAFLD and to determine the factors affecting the progression of the disease as well as the success of different treatment strategies.

18 years of age All Phase N/A
G George Lau, MD

Nonalcoholic Steatohepatitis in Chinese Children

Nonalcoholic steatohepatitis (NASH) is now recognised as an increasing clinical problem in children. Steatosis without significant liver cell injury or fibrosis is the most common form of nonalcoholic fatty liver disease (NAFLD) in both adults and children. Studies in the adult population have variably suggested that steatosis is a benign …

1 - 18 years of age All Phase N/A
O Oliver Tschopp, MD

Prospective Cohort Study in Patients With NAFLD

To assess the importance of intracellular signalling pathways and its deregulation in adiposity and diabetes-related insulin resistance, liver tissue samples of patients suffering from non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH)will be analyzed prospectively from a liver tissue bank.

18 years of age All Phase N/A
R Rosemary Mullett

Investigating Pathological Mechanisms in Non-alcoholic Fatty Liver Disease

To identify key characteristics of the tissue resident and peripherally circulating immune-phenotype in addition to blood markers, metabolic profile, faecal and oral microbiota in non-alcoholic fatty liver disease

18 years of age All Phase N/A
A Amira Mohamed, PhD

Role of Regulatory B Cells in the Pathogenesis of Metabolic Associated Fatty Liver Disease

To evaluate the role of regulatory B cells in the pathogenesis of metabolic associated fatty liver disease patients.

18 - 80 years of age All Phase N/A
M Minghui Li

Establishment of Precise Histological Evaluation Criteria for NASH Fibrosis Reversal

Collect confirmed cases of NAFLD patients and enroll them in the study. Select patients with NASH and fibrosis stage F2-4 confirmed by liver biopsy, and collect clinical and pathological data for relevant evaluation and definition. Establish a NASH "fibrosis reversal" pathological evaluation system, based on a new reversal standard, establish …

18 - 70 years of age All Phase N/A
A Allan Vaag, MD, PhD

Increased Risk of Non-alcoholic Fatty Liver Disease in Low Birth Weight Individuals

The investigators recently demonstrated a increase in liver fat in early middle-aged LBW compared to normal birth weight (NBW) men, and 20% of the LBW - but none of the normal birth weight (NBW) - men had previously unknown non-alcoholic fatty liver disease (NAFLD). Here the investigators will further examine …

35 - 40 years of age All Phase N/A
E Endrit Shahini, MD

Use of Blood Biomarkers for the Early Diagnosis of Hepatocellular Carcinoma (HCC)

The objective of this observational study is to evaluate the clinical utility of the combined assay of 3 biomarkers: α-FP, α-FP-L3 and DCP (simultaneously measured by µTASWakoTM i30 automated in vitro diagnostic system) in high-risk subjects to develop this neoplasm. In particular, it aims to: Evaluate the clinical utility of …

years of age All Phase N/A

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