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Periodontitis Clinical Trials

A listing of Periodontitis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 132 clinical trials
L Luca Ramaglia

Application of Hyaluronic Acid in the Treatment of Periodontitis

The aim of the present investigation will be evaluated the healing of suprabony defects following surgical flap elevation and hyaluronic acid application respect to surgical flap elevation alone. A total of 80 patients will be enrolled, selected by inclusion and exclusion criteria and randomly divided in two groups: hyaluronic acid …

18 - 70 years of age All Phase N/A
C Conchita Martin, Prof

Effect of MOPs During Orthodontic Movement in Periodontitis Patients

Micro-osteoperforations (MOPs) cause cortical bone injuries and consequently increase the expression of inflammatory mediators, allowing for increased bone and periodontal ligament remodeling associated with orthodontic movement. It remains unclear the effect of orthodontic intrusion combined with MOPs application on teeth with reduced periodontium. The general objective will be to determine …

18 - 80 years of age All Phase N/A

Antimicrobial Photodynamic Therapy With ICG-Loaded Nanoparticles for Periodontitis Management

To better understand and treat your gum disease, dentists now use a system that stages its severity and grades its speed, rather than using old labels. The recommended first step is almost always a deep cleaning, which is very effective. However, because some bacteria can hide from cleanings and antibiotics, …

36 - 50 years of age All Phase 2
R Ritika Arora

Validation of Hindi Version Oral Health Impact Profile for Periodontitis

Translation of OHIP-CP questionnaire in Hindi language will be done. Patients recruited will undergo clinical examination and recording of periodontal parameters (Pocket probing Depth and Clinical Attachment Loss) will be recorded to determine stage and grade of periodontitis. Patients will be given OHIP-CP Hindi questionnaire. Content Validity and Construct validity …

18 years of age All Phase N/A
R Rok Gašperšič, PhD

Electrolysed Saline Rinse As an Adjunct for Treatment of Chronic Periodontitis

The study will be conducted as a prospective, double-blind, parallel, randomized, placebo-controlled study at the Dental Clinic of University Medical Centre Ljubljana. It will involve a one-month test period, during which the test subjects will use either placebo, Electrolysed Oxidising Saline (EOS) or chlorhexidine (CHX) in the form of a …

18 - 80 years of age All Phase N/A
A Alexandria university

Active Oxygen Releasing Gel With Photodynamic Therapy in Treating Stage III Periodontitis

Periodontitis is a serious gum disease that can damage the tissues supporting the teeth. The standard treatment is scaling and root planing of the teeth and roots. However, in some patients, this treatment alone may not fully control inflammation and harmful bacteria. This study aims to evaluate whether adding an …

30 - 70 years of age All Phase N/A
d dalia ghalwash, phd

Clinical Efficacy of Saffron Mouth Rinse in Periodontitis Patients With Renal Disease

The commensal oral bacteria are responsible for the initiation and propagation of the disease through the process of dysbiosis, or microbial imbalance. The disease proceeds cyclically with periods of activity and quiescence until therapeutic action is taken, or the tooth and surrounding structures are destroyed by the disease process that …

19 years of age All Phase N/A
M Meng Wan, doctor

Human Dental Pulp Mesenchymal Stem Cells for the Treatment of Chronic Periodontitis Patients

The primary objective:To evaluate the efficacy of different administration protocols of human dental pulp mesenchymal stem cells for the treatment of chronic periodontitis patients. The secondary objective:To evaluate the safety of different administration protocols of human dental pulp mesenchymal stem cells for the treatment of chronic periodontitis patients. The exploratory …

18 - 65 years of age All Phase 2

Effectiveness of SRP+ Lipo-curcumin Gel for the Treatment of Stage III Periodontitis.

The aim of the present study is to clinically and radiographically compare the effectivness of Scaling and Root Plannig (SRP) in association with lipo-curcumin gel (LC) respect SRP+ lipo-gel (L), SRP+ discharged (D) gel and SRP alone. This study will be designed as a randomized clinical trial of 12-month duration. …

18 - 80 years of age All Phase N/A
G Gabriela Alessandra da Cruz Galhardo Camargo, PhD

Clinical and Microbiological Evaluation of Laser Therapy in the Treatment of Periodontal Disease in Stages III and IV

The aim of this clinical trial is to evaluate photodynamic therapy and photobiomodulation in the periodontitis treatment. To evaluate the clinical and microbiological response of conventional periodontal treatment associated with photodynamic therapy and photobiomodulation with red or infrared laser. Participants will receive periodontal treatment carried out with the use 0.005% …

18 - 70 years of age All Phase N/A

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