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Periodontitis Clinical Trials

A listing of Periodontitis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 132 clinical trials
B Bengi Gülgü

Effect of Different Root Canal Sealers on Oxidative Stress Markers

The goal of this clinical trial is to primary purpose investigate and compare oxidative stress markers in patients with chronic apical periodontitis treated with different root canal paste in a single session. The main questions it aims to answer are: Is there a change in oxidative stress markers measured from …

18 - 45 years of age All Phase N/A
M Mikko Kylmänen, Master of Health Care

Targeting of Preventive Treatment for Adolescents at Risk of Oral Diseases

The aim of the study is to identify adolescent patients that are at risk of developing oral diseases, and to assess if targeted preventive oral treatment with antibacterial dual-light therapy as an adjunctive treatment method can have a positive impact in preventing oral diseases from emerging.

14 - 16 years of age All Phase N/A
L Luca Ramaglia

Treatment of Intraosseous Periodontal Defects With Amelogenins

The aim of the present investigation will be evaluate the healing of periodontal intraosseous defects following Minimally Invasive Non Surgical Debridement (MINSD) and application of amelogenins, compared to MINSD alone. A total of 22 patients will be enrolled, selected by inclusion and exclusion criteria and randomly divided in two groups: …

18 - 70 years of age All Phase N/A
A Andrea Scribante, Associate Professor

Para-Probiotic Oral Care in Periodontal Patients With Type 2 Diabetes

This randomized controlled clinical trial aims to evaluate the effectiveness of a para-probiotic-based oral care protocol in improving periodontal health and glycemic control in patients with type 2 diabetes mellitus (T2DM). A total of 40 adult patients (aged 18-70) with diagnosed periodontitis and T2DM will be enrolled and randomly assigned …

18 - 70 years of age All Phase N/A
M Melisa Vera Melisa Vera DSD

Effect of Periodontal Treatment on Metabolic Control in Patients with Type-2 Diabetes Mellitus Treated in the Cardiovascular Healt Program

The objective of this clinical trial is to evaluate the effect of periodontal treatment on the reduction of glycated hemoglobin levels in adult patients with concurrent type 2 diabetes mellitus and periodontitis. Non-surgical periodontal treatment and the application of a quality of life survey will be performed and then controls …

18 years of age All Phase N/A
J Jue Shi, Doctor

Using Xenograft Combined With Barrier Membrane to Improve the Formation of Deep Periodontal Pockets

To evaluate the clinical effect of site preservation after third molars extraction by using tooth extraction of third molars with site preservation using bio-oss and bio-guide in preventing the formation of deep periodontal pockets in the distal of second molars.

26 - 45 years of age All Phase N/A
E Elena Calciolari, DDS, MS, PhD

Hyaluronic Acid and Polynucleotides for Supra-bony Defects

The goal of this pilot study is to describe the early wound healing molecular events and the vascularization pattern associated with the treatment of supra-bony defects with access flap alone or in association with a combined formulation of hyaluronic acid and polydeoxyribonucleotides gel.

18 years of age All Phase N/A
A Angela A Palaiologou-Gallis, DDS., MS.

The Effect Of Enamel Matrix Derivatives On Gingival Tissue Thickness

Scientists do research to answer important questions which might help change or improve the way we do things in the future. The investigators know that using Enamel Matrix Derivatives results in thicker gum tissues around teeth. This study will test to see if using EMD around implants results in thicker …

18 - 18 years of age All Phase N/A

Extending Dental Care to Nursing Home Residents to Reduce Mouth Infections and Incidence of Pneumonia and Improve Diabetic Glucose Control

The goal of this study is to learn if dental infection control treatment delivered to older adult nursing home residents at their place of residence will result in : improved dental health reduced risk of pneumonia better glucose control for diabetic patients compared to the pre-project dental and general health …

60 - 100 years of age All Phase N/A
F For more information at the NIH Clinical Center contact Office of Patient Recruitment (OPR)

Oral Bacteria and Immune System Problems Involved in Gum Disease (Periodontitis)

Background Gum disease is a condition in which the tissue around the tooth root becomes swollen and infected. This condition can cause tooth loss if it is not treated. Who gets gum disease and how bad it will be depends on (1) the different bacteria in the mouth and (2) …

7 years of age All Phase N/A

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