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tobacco-use-disorder Clinical Trials

A listing of tobacco-use-disorder medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 103 clinical trials

Low Intensity Focused Ultrasound for Tobacco Use Disorder: High Resolution Targeting of the Human Insula

The goal of this clinical trial is to to inhibit the dorsal anterior insula (dAI) with low intensity focused ultrasound (LIFU) to determine the causal role for the dAI in smoking cue induced craving in individuals with tobacco use disorder (TUD); smoking cue induced craving is a clinically important behavior …

18 - 65 years of age All Phase N/A
S Sabine Vollstädt-Klein

Increasing Smoking Cessation Success Through Sleep-amplified Memory Consolidation

The goal of this subproject is to examine the hypothesized improvement of treatment with chess-based training and sleep enhancement, both together and on their own, in smokers. Participants will undergo fMRI measurements, sleep monitoring. They will then be assigned to one of the four experimental groups, including high-intensity interval training …

18 - 65 years of age All Phase N/A
S Shirley Plucinski

Nicotine Regulation for Dual Users of E-cigarettes and Cigarettes

Cigarette smoking remains the leading cause of preventable morbidity and mortality in the US. Use of multiple tobacco products is becoming increasingly prevalent, with dual use of e-cigarettes and cigarettes representing the most common combination. Though e-cigarettes are not without risk, completely switching from cigarettes to e-cigarettes likely reduces risk …

21 years of age All Phase 2
N Neal M Doran, PhD

DBT for Smoking Cessation in High Risk Veterans

Individuals prone to suicidality are typically excluded from tobacco cessation interventions even though they are disproportionately likely to smoke, and even though smoking cessation has been linked to improved mood and reduced risk of suicide. This trial enrolls Veteran smokers at high risk for suicide, and assigns them to receive …

18 years of age All Phase N/A
Y Yousif Alsaadi, B.S

A Future Thinking Intervention for Comorbid Tobacco Use Disorder and Bipolar Disorder

Future Self-BD is a 6-session virtual intervention that encourages participants to vividly generate personal and positive future events that they anticipate may be benefited by smoking cessation. Each session will be conducted on HIPAA-compliant Zoom and led by the PI (Dr. Gold).

18 years of age All Phase N/A
F Fulya DEMIRHAN, Res. Ass.

Effects of Exercises on Functional Capacity

In this study, the researchers aim to investigate the effects of strengthening and respiratory exercises on the face and online on functional capacity.

18 - 40 years of age All Phase N/A
D Dylan E Kirsch, PhD

Examining the Effects of Cytisinicline on Neural Substrates of Cigarette Cue-reactivity

This study will randomize 64 non-treatment seeking individuals who smoke cigarettes daily in a double-blind, placebo-controlled laboratory study testing the effects of cytisinicline on the neural substrates of cigarette cue reactivity.

18 - 65 years of age All Phase 2
P Pallav Pokhrel, PhD, MPH

Quit-Smoking Study for Native Hawaiians

This study aims to help Native Hawaiian adults quit smoking by testing two common methods: nicotine gum and group-based counseling. Participants will be assigned to one of three groups: (1) nicotine gum only, (2) group counseling only, or (3) a combination of both. The study will take place at public …

18 - 80 years of age All Phase N/A
M Madeline Martinez Rivas, PhD

Smoking Cessation CM for Veterans With or at Risk for Cancer

Tobacco use among US Veterans poses significant health problems and challenges to their overall well-being. The aim of this project is to evaluate the effectiveness of a program called Contingency Management (CM) in helping Veterans quit smoking during lung cancer screening or cancer care at VA clinics. CM is a …

18 years of age All Phase N/A
E Ellen Herbst, MD

Contingency Management for Veteran Smokers Undergoing Major Elective Surgery

The goal of this study is to design and test the first mobile contingency management (CM) smoking cessation intervention for military Veterans undergoing major elective surgery. Smoking is the leading risk factor for postoperative complications and is associated with longer hospital stays, reoperations, and 30-day mortality. Smoking rates among patients …

18 years of age All Phase N/A

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