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tobacco-use-disorder Clinical Trials

A listing of tobacco-use-disorder medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 102 clinical trials
D Dustin C Lee, PhD

Oral Cannabidiol for Tobacco Cessation

Cannabidiol is a compound found in cannabis plants that is well tolerated, has low abuse liability, and might be an effective medication to promote tobacco cessation. This clinical study will use a validated approach for screening tobacco cessation medications to determine if oral cannabidiol increases short-term tobacco abstinence, and evaluate …

18 - 65 years of age All Phase 1

Perceptions of E-Cigarettes and Synthetic Cooling Agents, The ICE Study

This study evaluates how synthetic cooling additives like WS-3 and WS-23 impact e-cigarette perceptions, use behavior, and toxicant exposure.

21 - 29 years of age All Phase N/A

Evaluation of Low and High Nicotine Tobacco Free Nicotine Pouches

Tobacco-free oral nicotine pouches (such as Zyn brand) are a less harmful alternative to cigarette smoking. Pouches, however, contain nicotine, and addictive substance that is not risk-free. The present study is evaluating how well nicotine pouches, at different nicotine levels, help people switch away from smoking cigarettes. People who smoke …

21 years of age All Phase N/A
C Cezary Kępka, MD PhD

Effects of Switching From Cigarettes to Tobacco Heating System on Coronary Atherosclerosis Progression

Objective To evaluate the impact of heated versus combustion tobacco products on progression of atherosclerosis in patients with CAD unable(unwilling) to quit smoking. Rationale Despite the efforts to curb smoking and full awareness of its deleterious health impact, smoking remains a significant contributor to morbidity and mortality. Some health impact …

18 - 75 years of age All Phase N/A
P Peter S Hendricks, PhD

Early Withdrawal Exposure and Negative Affect Withdrawal (NAW) Regulation Training for Smoking Cessation

Smoking remains the single most preventable cause of morbidity and mortality in the United States, accounting for approximately half a million deaths every year. The current study will investigate the efficacy and mechanisms of change of a novel smoking cessation intervention. The current study will thus provide essential information regarding …

18 years of age All Phase 3
J Jewel Jones, MBBS

Effect of Yoga on Reducing Craving in Tobacco Dependent Individuals

Yoga is a culturally acceptable practice that can reduce craving and help people quit tobacco. There is a need to evaluate the feasibility of implementation of a welldesigned yoga protocol to address craving in individuals who use tobacco in India.

18 - 65 years of age Male Phase N/A
C Cheri Green, EdD, MSN, RN

Harm Reduction for Smokers With Mental Illness

To compare the efficacy of e-cigarette (e-cig) provision with or without behavioral support (SWITCH IT) delivered via telehealth to reduce harm among smokers with MI who cannot quit smoking and are not ready to pursue cessation treatment, and to examine self-regulation (using e-cigs instead of cigarettes to cope with stress/distress …

21 years of age All Phase N/A
N Nicolle M Krebs, MS

Use of Nicotine Pouches Among Daily Smokers

The purpose of this clinical trial is to understand the health effects of a new oral nicotine pouch, and also to understand if this product can help reduce traditional cigarette smoking. The main aims are: Understand the impact of nicotine pouch use on toxicant exposure biomarkers, and indicators of potential …

21 - 70 years of age All Phase N/A
H Heidi Hutton

C-Raven, a Virtual Tobacco Cessation Intervention in Residency Clinics

In a residency clinic in Baltimore, the investigators propose to conduct a pilot RCT comparing a) an avatar-delivered computerized intervention (CI) for tobacco cessation augmented with CHW support and navigation to lung cancer screening to b) a waitlist control. With a sample of participants from the residency clinic (N=30), the …

50 years of age All Phase 4
F Fulya DEMIRHAN, Res. Ass.

Exercise Training for Smoking Students

Smoking can damage lung functions as a result of high carbon monoxide and low hemoglobin oxygen carrying capacity in the blood. Smoking between young people continues to increase, which can cause respiratory function problems and lung diseases at an early age. In the studies, it has been seen that smoking …

18 - 40 years of age All Phase N/A

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