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tobacco-use-disorder Clinical Trials

A listing of tobacco-use-disorder medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 103 clinical trials

Positive Psychology for Smoking Cessation

This study will examine how Positive Psychotherapy (PPT) may help people interested in quitting smoking, quit.

21 years of age All Phase N/A
L Lauren Morris, MHS

Effect of Cannabis on E-Cigarette Use Behavior

The purpose of this study is to determine the impact of tetrahydrocannabinol (THC) administration on motivational, subjective, and physiological effects of electronic cigarettes. The study's goals are to test demand for e-cigarettes, tobacco craving, affect, heart rate, blood pressure, expired breath carbon monoxide, and cognitive performance. Researchers will compare multiple …

21 years of age All Phase 1
Z Zeynep ÖZTÜRK, PHD

Effectiveness of Smoking Cessation Education

Smoking is an important psychosocial problem that concerns society. It is reported that 1.3 billion people use tobacco products in the world and approximately 6 million people lose their lives due to smoking every year. Despite the high mortality rate, smoking addiction is shown as one of the biggest preventable …

18 years of age All Phase N/A
Y Yu Chen, PhD

Neural Mechanisms Connecting Deficient Sleep and Smoking Relapse

The study aims to investigate whether behavioral interventions promote cessation in adult smokers by ameliorating negative emotions and improving self-control and identify the neural markers of these effects.

18 - 50 years of age All Phase 2
N Nina Cooperman

Motivational Interviewing and Mindfulness-Oriented Recovery Enhancement

The purpose of this study is to 1) examine barriers and facilitators to implementation of MI and MORE for polysubstance use and evaluate strategies for optimizing training, fidelity, and clinic uptake, and 2) evaluate patient outcomes related to the effectiveness of MORE decreasing opioid, tobacco, and other drug use.

18 years of age All Phase 3
T Teresa A Evans-Campbell, MSW, PhD

Journey of Transformation Curriculum for Native American Youth

The investigators will conduct a waitlist control trial to test the efficacy of the Journey of Transformation-Native Youth Health Leadership Program (JOT) in terms of delaying or reducing tobacco and other substance use and improving sexual health.

13 - 16 years of age All Phase N/A
X Xingbao Li, M.D

RTMS Targets Neural Circuits for Smoking Cessation

Cigarette smoking is a significant public health concern. Transcranial magnetic stimulation (TMS) is a non-invasive form of brain stimulation that has already displayed remarkable potential for producing novel, non-pharmacological interventions for depression and cigarette smokers. In this study, we will use brain MRI to guide TMS therapy for smoking cessation.

18 - 60 years of age All Phase 1/2
N Nichea S Spillane, Ph.D.

Developing a Positive Approach to Substance Use Prevention in North American Indian Adolescents

The overall objective of this project is to develop and obtain preliminary data on acceptability, feasibility, and initial efficacy of Native PATHS. This work is guided by the stage model guidelines for treatment development and adaptation 25. Stage 1a will occur in two sequential steps. First, the investigators will recruit …

10 - 14 years of age All Phase N/A
J Janet Audrain-McGovern, Ph.D.

The Role of Flavor in the Substitutability of E-cigarettes for Combustible Cigarettes Among Persistent Smokers

This between-subjects study aims to evaluate the effect of flavor on initial and sustained switching from combustible cigarettes to e-cigarettes among 210 cigarette smokers. After measuring baseline cigarette smoking rate, participants will be randomized to a six-week regimen of fruit-flavored, tobacco-flavored, or menthol-flavored e-cigarettes and be instructed to switch (versus …

21 years of age All Phase N/A
N Neal Associate Chief of Staff- Research

Nonendoscopic Screening for Barrett's Esophagus in Veterans Without Chronic Reflux

The veteran population is at increased risk for EAC and its precursor lesion, Barrett's esophagus (BE), due to increased prevalence of disease risk factors compared to the general population. BE is traditionally diagnosed only when patients undergo endoscopy with biopsies. However, due to the high cost of endoscopy and the …

40 - 85 years of age All Phase N/A

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