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Dysmenorrhea Clinical Trials

A listing of Dysmenorrhea medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 215 clinical trials
S Sabrina Coppola

Developing a Novel Human Laboratory Paradigm for AUD Medication Screening

The intent of the study is to develop two versions of the 'ability to resist' drinking model designed to screen Alcohol Use Disorder (AUD) medications.

21 - 65 years of age All Phase N/A
F For more information at the NIH Clinical Center contact Office of Patient Recruitment (OPR)

PET Imaging of Phosphodiesterase-4B (PDE4B) in Alcohol Use Disorder

Background People with alcohol use disorder (AUD) also often have bouts of depression called major depressive episodes (MDEs). People having MDEs have been found to have low levels of a protein called PDE4B in the brain. Researchers want to find out if people with AUD also have low levels of …

18 - 70 years of age All Phase 1
L Lilou DUQUET, PhD student

Effect of Adapted Physical Activity on Sleep Quality in People With Alcohol Use Disorder

This feasibility study aims to assess interest, recruitment, and adherence to a supervised physical activity (APA) program among individuals with Alcohol Use Disorder (AUD). It also investigates the program's impact on sleep quality and efficiency. Key objectives include evaluating recruitment feasibility, assessing randomization acceptance, quantifying adherence rates, and identifying sensitive …

18 - 65 years of age All Phase N/A
C CORINNE DANO

Comparison of the Effectiveness of Two Psycho-physical Interventions: Mindfulness Based Relapse Prevention (MBRP) and Unguided Meditative Relaxation in Patients With Alcohol Use Disorder

Alcohol use disorder (AUD) is the second highest preventable cause of death in France. Only 3% of patients are prescribed approved drugs for reducing alcohol consumption or maintenance of abstinence. Increasing evidence supports the efficacy of psychotherapies such as cognitive and behavioral therapies (CBT) in AUD. However, some patients are …

18 years of age All Phase N/A
R Raeghan Mueller

Alcohol Use Disorder and Cannabidiol

This is a double-blind, placebo-controlled, parallel group study designed to assess the efficacy of full spectrum CBD and broad spectrum CBD, compared to a placebo control (PC), to reduce drinking in participants with alcohol use disorder. If eligible for the study, subjects will be randomized to receive one of the …

21 years of age All Phase 2/3
N Nicolas Garel, MD MSc

ACT_for Alcohol Use Disorder and Depression

Alcohol use disorders (AUDs) and depressive disorders frequently coexist, complicating the clinical management of patients suffering from them. Taken separately, these two disorders have a significant prevalence in the population, and a recent meta-analysis concluded that coexistence could reach 1 in 5 patients (20.8%). This comorbidity represents a considerable challenge, …

18 - 70 years of age All Phase N/A

Orexin Receptor Antagonism for the Treatment of Alcohol Use Disorder and Stress-Related Drinking

The goal of this clinical trial is to learn if, how, and for whom suvorexant (SUV) works to treat alcohol use disorder (AUD). The main questions it aims to answer are: Is SUV effective for AUD? Does SUV dampen stress reactivity? Can the researchers develop a biomarker for SUV treatment …

18 - 65 years of age All Phase 2
P Peter Kosa, MBBS

Deep Brain Stimulation to Understand and Treat Addiction

This study is testing whether deep brain stimulation (DBS) can safely help people with severe alcohol use disorder who have not improved with standard treatments. DBS uses small electrical signals to change activity in brain areas linked to craving, self-control, and emotion. The study will test whether this treatment can …

18 - 60 years of age All Phase N/A

Neurobehavioral Mechanisms of Psilocybin-assisted Treatment for AUD

This is a double-blind, randomized, placebo-controlled Phase 2 mechanistic clinical trial designed to evaluate the therapeutic neural mechanisms of psilocybin in patients with alcohol use disorder (AUD), and to determine whether further studies are warranted to study the relationship of any such effects to clinical improvement in AUD symptoms. The …

18 - 65 years of age All Phase 2
Z Zee Petrie

Virtual Reality (VR) NATURE - Alcohol Use Disorder (AUD)

This pilot randomized clinical trial will evaluate the feasibility, acceptability, and preliminary effectiveness of immersive Virtual Reality (VR) nature intervention among adults with at least moderate depression symptoms enrolled in an intensive outpatient Program (IOP) for Alcohol Use Disorder (AUD). The study hypotheses: VR-based nature immersion will be feasible, acceptable, …

18 years of age All Phase N/A

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