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pain Clinical Trials

A listing of pain medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 2,817 clinical trials
E Enrico De Martino, MD

Mechanistic Study of Personalized rTMS in Chronic Pain

Previous research has demonstrated that repetitive magnetic brain stimulation can be an effective adjunctive treatment for several conditions, including chronic pain. However, current stimulation protocols are typically standardized and do not account for individual variability in brain function. This uniform, one-size-fits-all approach results in only about 40% of patients experiencing …

18 - 80 years of age All Phase N/A
H Hanna Kalajas-Tilga, PhD

The Effect of Pain Education Group Therapy and Its Impact on Chronic Pain, Kinesiophobia, and Physical Activity

The goal of this clinical trial is to learn if pain knowledge group intervention among chronic pain patients would influence their level of physical activity, pain intensity, depression, kinesiophobia and central sensitization. The main question it aims to answer is: Primary hypothesis: pain education will decrease participants' depression and pain …

16 - 65 years of age All Phase N/A
J Juan Ignacio Reoyo, doctor

Clinical Trial to Evaluate the Efficacy and Safety of Platelet-rich Plasma Infiltration in Chronic Omalgia

The experimental group will receive intralesional injections of platelet-rich plasma, evaluating its ability to relieve pain and provide sustained improvement through biological modulation of the joint and tendon environment. In contrast, the control group will be treated with a combination of betamethasone and ropivacaine, representing the current standard of care …

35 - 75 years of age All Phase 3
J Juan V-M Vicente Mampel, PhD

Managing Chronic Spinal Pain With Exercise and Neuromodulation

Chronic spinal pain is a multifaceted condition frequently characterized by an absence of discernible structural causes, manifesting in symptoms such as significant disability and diminished quality of life. Persistent Spinal Pain Syndrome Type 2 (PSPS-T2) represents a common variant, implicating both peripheral and central nervous system mechanisms. This study investigates …

18 - 70 years of age All Phase N/A
J Javier Torres Alonso, PDI

Efficacy of Pain Science Education Combined With Exercise in Older Adults With Chronic Pain

As people live longer, long-term pain becomes more common in old age. This type of pain can greatly affect quality of life, reduce independence in daily activities, and diminish overall well-being. This study is part of a project called PReGe, which aims to help older adults age actively and healthily …

65 years of age All Phase N/A

Brief Mindfulness Intervention for Chronic Pain in Ukraine

This is a pragmatic randomized controlled trial comparing a single 15-minute mindfulness-based intervention to usual care for patients with chronic pain in Ukraine being seen in a pain clinic.

18 years of age All Phase N/A
S Staci Gruber, PhD

PAIN: A Project Assessing the Impact of a Novel Cannabinoid Product

This study is a clinical trial of a high-cannabidiol (CBD) sublingual product compared to placebo for 9 weeks in patients with chronic pain conditions. The study will assess the impact of CBD on chronic pain symptoms, conventional medication use, clinical state, quality of life, cognition, and biomarkers.

21 years of age All Phase 2
A André Mouraux, PhD

Assessing Chronic Pain Patient Preferences

The goal of this study is to ask chronic pain patients their preferences regarding which side effects of pain medications are least acceptable in relation to their pain relief benefits. This information may help in the selection of improved treatment options in the future.

18 years of age All Phase N/A
O Osman Hakan Gunduz, Prof. MD

Evaluation of Alexithymia in Chronic Pain Patients With Spinal Cord Stimulation

The purpose of this study is to investigate the relationship between alexithymia levels and clinical parameters, including pain intensity and quality of life, in chronic pain patients treated with spinal cord stimulation (SCS). Chronic neuropathic pain can lead to psychological distress and decreased quality of life. While SCS is an …

18 years of age All Phase N/A
N Nita Hoxha, MBA

POP SINGER Randomized Clinical Trial

Conduct a feasibility randomized controlled trial (N = 130, 65 per group) comparing the POPSINGER music therapy (MT) intervention to yoga.

18 years of age All Phase N/A

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