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pain Clinical Trials

A listing of pain medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 2,757 clinical trials
Z Zak Sturgill

Insula Neuromodulation for Chronic Neuropathic Pain

This study will comprehensively investigate the insula as a brain target for neuromodulation to treat chronic neuropathic pain.

18 - 80 years of age All Phase N/A

Novel Stimulation Patterns to Improve the Effectiveness of Spinal Cord Stimulation

The goal of this study is to compare pain outcomes achieved by spinal cord stimulation (SCS) using time varying stimulation patterns with pain outcomes achieved by current standard of care SCS.

22 years of age All Phase N/A

Analgesic Effectiveness of Capsaicin 8% Cutaneous Patch in Children

This study concerns children aged to 12 to 17-years with local chronic neuropathic pain after trauma or surgery. It is a multicentric randomized controlled superiority trial in parallel arms : experimental arm: Capsaicin 8% cutaneous patch controlled arm : Hydrocolloid dressing Treatment with capsaicin application is realized at baseline, and …

12 - 17 years of age All Phase 3
M Mohamed ElMeligie, Ph.D

Consensus-Based vs. Standardized Physiotherapy for Fibromyalgia

This study compares a new, consensus-based physiotherapy program to standard physiotherapy for people with fibromyalgia. The new program uses recommendations from experts, including education about pain, personalized exercise, and strategies to improve coping skills. We will measure how much pain people have, how well they can function, and their beliefs …

18 - 65 years of age All Phase N/A

Cryoablation Combined With Stereotactic Body Radiation Therapy for the Treatment of Painful Bone Metastases, the CROME Trial

This trial compares cryoablation combined with stereotactic body radiation therapy to stereotactic body radiation therapy alone to see how well they work in treating patients with pain from cancer that has spread to the bones (bone metastases). Bone is a common site of metastasis in advanced cancer, and bone metastases …

18 years of age All Phase N/A

Study to Evaluate Safety of C-1101 Versus Sterile Saline in Adults With Chronic Painful Lumbosacral Radiculopathy

The purpose of this study is to evaluate the safety and tolerability of C-1101 administered as a single dose, transforaminal epidural injection compared to sterile saline

18 - 65 years of age All Phase 1
M Maxwell Slepian, PhD, C Psych

Online Psychology Program for Chronic Pain After Surgery

This project will evaluate the feasibility of a new fully self-guided online Acceptance and Commitment Therapy (ACT) program entitled Advancing Online Psychology Tools for the Transitional Pain Service (ADOPT-TPS), developed on an online health application platform called Manage My Pain (MMP). The ACT program is designed to teach mindfulness skills …

18 - 80 years of age All Phase N/A
R Ruggero D'Anastasio, Full Professor

Mindfulness-based Rehabilitation in a University Museum Setting to Reduce Pain and Improve Quality of Life in Women With Fibromyalgia: a Randomized Controlled Trial

This research study aims to investigate whether art and integrative medicine, within a unique setting like a university museum, can offer a new approach to help women suffering from fibromyalgia. Fibromyalgia is a chronic condition causing widespread pain and other symptoms such as fatigue and sleep disturbances. The question this …

18 - 60 years of age Female Phase N/A
H HOPE Study

HOnest Placebos With Explanations: Evaluating Open-Label Placebos for Chronic Pain

The goal of this clinical trial is to examine the effect of rationale condition when taking open-label placebos on pain by 1) comparing each rationale to the no rationale control condition and the no treatment control condition; and 2) comparing the rationale conditions to each other. We also aim to …

18 - 89 years of age All Phase N/A

Efficacy of Gabapentin in Treating Pain in Children With SNI (Gabapentin Trial)

Children born with severe brain-based developmental disabilities frequently experience persistent unexplained periods of pain and irritability, often compounded by a limited capacity to communicate their distress. The investigators call this entity Pain and Irritability of Unknown Origin (PIUO). The rationale of this trial is to identify the clinical effect size …

6 - 18 years of age All Phase 2

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