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pain Clinical Trials

A listing of pain medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 2,825 clinical trials
J Javier Torres Alonso, PDI

Efficacy of Pain Science Education Combined With Exercise in Older Adults With Chronic Pain

As people live longer, long-term pain becomes more common in old age. This type of pain can greatly affect quality of life, reduce independence in daily activities, and diminish overall well-being. This study is part of a project called PReGe, which aims to help older adults age actively and healthily …

65 years of age All Phase N/A
B Brianna Krause, MS

Pilot Study: Impact of Biomarker-Guided Dietary Supplementation on Quality-of-Life Measures in Subjects With Chronic Pain

The goal of this study is to use pain-specific urine biomarkers to evaluate how daily nutritional supplementation with biomarker guided formulas effect, quality of life and urinary biomarker scores in chronic pain patients. Assessing the effect of biomarker guided supplementation on pain specific biomarkers through changes in urinary biomarker scores …

18 - 75 years of age All Phase 2
E Eduardo Fernández Jiménez, PhD

Effectiveness and Implementation of a Digital Intervention for Pediatric Chronic Pain Co-designed With Patients

Children and adolescents with chronic pain often lack a proper diagnosis and treatment. Research has shown that, if left untreated, it usually doesn't resolve and continues through adulthood. The goal of this multi-phase study is to co-develop (with patients), test, and implement a smartphone app called "Digital Solution for Pain …

12 - 17 years of age All Phase N/A
L Lidia Del Piccolo

MobACT: An Internet-Based Intervention for Chronic Pain Patients

Chronic Pain (CP) is a condition characterized by pain that lasts or recurs for more than three months in one or more parts of the body. This type of pain is often accompanied by emotional distress and difficulties in daily functioning, which can interfere with a person's ability to carry …

18 years of age All Phase N/A
A Amelie ya

Motivational Behavioral and Functional MRI Impairment in Patients With Chronic Neuropathic Pain

The main hypothesis of this study is that the alteration of the reward circuitry underlying the motivational deficit in chronic pain patients compared to healthy subjects results in a decrease in the capacity for reward learning. The fMRI studies have shown that this type of learning depends on the dopaminergic …

18 years of age All Phase N/A
K Kate Jochimsen, PhD, ATC

Open Pilot Trial of a Mind-Body Intervention for Patients With Chronic Hip Pain

The goal of this study is to conduct a feasibility open pilot study (N=5) of HIPS with virtual exit interviews among adult patients with chronic hip joint-related pain (HRP). We will use this mixed methods information to assess the feasibility, credibility, and acceptability of the HIPS intervention and optimize the …

18 years of age All Phase N/A
P Peter Ladlow, PhD

Is Low-load Resistance Training With Blood Flow Restriction Feasible During Rehabilitation of Military Personnel With Lower Limb Injuries? Phase One RCT.

Pain can be one of the primary limiting factors to progress following musculoskeletal injury and may be caused by trauma or degenerative changes. There are few exercise rehabilitation interventions able to relieve pain, thereby reducing the number of military personnel fit for operations. Low load blood flow restriction (BFR) exercise …

18 - 55 years of age All Phase N/A
G Geovanne Mauro, PhD

Prospective Cohort of Single-dose Radiotherapy for Painful Bone Lesions in Multiple Myeloma

Multiple myeloma is a plasma cell neoplasm that can cause painful bone lesions. The main treatment for these lesions and pain control is radiotherapy, usually in daily fractions. In 2017, a phase III study proved the effectiveness of using a single dose of 8 Gy, but without description of several …

18 - 85 years of age All Phase N/A
C Chace Henning

Low-Dose Radiotherapy in Treating Painful Bone Metastases in Patients With Multiple Myeloma

This phase II trial studies how well low-dose radiotherapy works in treating bone pain in patients with multiple myeloma that has spread to the bone. Radiation therapy uses high energy x-rays, gamma rays, neutrons, protons, or other sources to kill tumor cells and shrink tumors. Low-dose radiotherapy may be more …

18 years of age All Phase N/A
S Sergey Motov, MD

Nebulized Ketamine to Nebulized Fentanyl for Treating Acute Painful Conditions in the ED

In situations where intravenous access is not readily available or is unobtainable and the intranasal route is not feasible, another non-invasive route of ketamine administration, such as inhalation via breath-actuated Nebulizer (BAN), is becoming a viable alternative. The BAN allows the controlled, patient-initiated delivery of analgesics in a measured and …

18 - 120 years of age All Phase 4

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