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pain Clinical Trials

A listing of pain medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 2,825 clinical trials
M Merve Koyuncu Cenikli

Which Patient Group Shows Greater Improvement With Patient Education Alone in Rotator Cuff-Related Shoulder Pain? - A Cohort Study

The primary aim of this study is to determine the clinical effectiveness of patient education alone in individuals with rotator cuff-related shoulder pain and to identify which patient subgroups benefit more from this approach. In addition, the translation and cultural adaptation of the "Patient Knowledge Questionnaire (PKQ-RCRSP)" into Turkish will …

18 - 65 years of age All Phase N/A
L Lech Dobija, PhD, PT

Comparison of the Immediate Effect of Passive vs. Passive-Active Hamstring Stretching on Flexibility in Patients With Chronic Low Back Pain

The goal of this clinical trial is to determine whether a combination of passive and active hamstring stretching (PAS) is more effective than passive stretching alone (PS) in improving flexibility in patients with chronic low back pain (CLBP). The main questions it aims to answer are: Does PAS lead to …

18 - 65 years of age All Phase N/A
Z Zarina Zahari

Effects of Combined Physiotherapy Management and Education

This observational study aims to determine the effects of combined physiotherapy programs and education in patellofemoral pain syndrome. The main questions it aims to answer are: Are there any effects of combined physiotherapy program among individuals with PFPS on: i) Pain ii) Muscle functions (strength, muscle bulk, flexibility) iii) Knee …

18 - 59 years of age All Phase N/A
B Benjamin Provencher, D.C., M.Sc.

The METRIC Study Protocol

The goal of this clinical trial is to test the effects of spinal manipulative therapy in individuals with chronic primary low back pain and determine the neurophysiological mechanisms underlying pain relief. The main questions it aims to answer are: • Is pain relief produced by spinal manipulative therapy in patients …

18 - 60 years of age All Phase N/A
J Jodi M Gilman, PhD

Cannabidiol for Reduction of Brain Neuroinflammation

This study will investigate whether cannabidiol (CBD), the primary centrally and peripherally active non-intoxicating compound in the cannabis plant, exerts anti-neuroinflammatory effects in patients with chronic low back pain (cLBP) with or without mild-to-moderate depression.

18 - 75 years of age All Phase 2
W Wenxin Wei

DBS of the SCC for the Treatment of Medically Refractory CLBP

The purpose of this study is to evaluate the feasibility and preliminary efficacy of deep brain stimulation of the subgenual cingulate cortex for the treatment of chronic medically-refractory low back pain using a randomized double-blind crossover design.

40 - 75 years of age All Phase N/A
B Barış NACIR, Professor Doctor

Comparison of the Effectiveness of Thoracolumbar Fascia Mobilization and Ultrasound-Guided Thoracolumbar Interfascial 5% Dextrose Injection in Patients With Chronic Low Back Pain

The aim of this study is to investigate the effects of thoracolumbar fascia mobilization and ultrasound-guided thoracolumbar interfascial 5% dextrose injection on pain, range of motion, disability, quality of life, proprioception, and fascial thickness and echogenicity in patients with nonspecific chronic low back pain. -Primary Objective: The primary objective is …

18 - 65 years of age All Phase N/A
P Philippe PR Richebé, MD, PhD

Dexmedetomidine Added to Ropivacaine Single Shot vs Continuous Interscalene Nerve Block

Arthroscopic shoulder surgery is increasingly performed in an outpatient setting and post-operative pain management is often a real challenge as those surgeries are well recognized for their high level of pain which often affects physical rehabilitation. The interscalene block is a largely used anesthetic technique to perform these surgeries whilst …

18 years of age All Phase N/A
A Ahmed El Abdelaal, Master

Ultrasound-guided Multilevel Erectorspinae Plane Block Versus Thoracic Epidural Analgesia for Prevention of Post Mastectomy Pain Syndrome for Breast Cancer Patients

The aim of this study is to compare the analgesic efficacy of multilevel erector spinae plane block (ESPB) vs thoracic epidural in modified radical mastectomy (MRM) regarding duration of analgesia, postoperative opioid consumption, effect on intraoperative fentanyl consumption, postoperative numerical pain rating scale and quality of life for the next …

18 - 65 years of age Female Phase N/A
I InSun Park, MD

Dual-chamber Patient-controlled Analgesia for Postoperative Recovery

Postoperative nausea and vomiting (PONV) are the most common complications that can occur after general anesthesia. Postoperative use of opioids and morbid obesity have been reported as risk factors of PONV. In this study, the investigators aimed to compare the degree of postoperative side effects and pain control when an …

19 - 65 years of age Female Phase N/A

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