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pain Clinical Trials

A listing of pain medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 2,825 clinical trials
M Merve Sarı, DDS

Outcomes of Pulpotomy and Root Canal Treatment in Teeth With Symptomatic Irreversible Pulpitis

The aim of this study is to evaluate total pulpotomy, radicular pulpotomy, and root canal treatment procedures in mandibular premolar and/or molar teeth with symptomatic irreversible pulpitis, in terms of both their effectiveness in controlling postoperative pain and their success rates. Materials and Methods: A total of 99 mandibular premolar …

18 - 45 years of age All Phase N/A
Y Yang Dr. Wu, M.D.

A Prospective Observational Study of First-Line Systemic Therapy Combined With Celiac Plexus Blockade for Advanced Biliopancreatic Cancer With Pain

This study is for patients with advanced bile duct or pancreatic cancer who are experiencing pain from their disease. The purpose of this research is to learn about the effects of combining a standard pain relief treatment (Celiac Plexus Block) with standard first-line cancer drugs. Patients in this study will …

years of age All Phase N/A
R Roland PEYRON, MD PHD

rTMS Efficacy Coupled With Mirror Therapy

Neuropathic pain is particularly difficult to treat with classic first-line drugs. Neuromodulation techniques using repetitive transcranial magnetic stimulation (rTMS) are useful alternative, but there is a need to improve their analgesic effect.Virtual reality mirror therapy has shown the capacity to alleviate pain and may be easily coupled with rTMS.The present …

18 - 85 years of age All Phase N/A

Physical and Functional Effects of Online Exercise Program on Musicians Playing Stringed Instruments

Musculoskeletal problems related to instrument playing or performance are frequently seen in musicians. Different interventions such as strength training, endurance training and yoga have been used in the management of these problems. The first specific exercise program for professional orchestra musicians was developed by Chan et al. However, it has …

18 - 65 years of age All Phase N/A
J Joshua Steinke

Immersive Healing: The Therapeutic Potential of Virtual Reality

Phantom limb pain (PLP) is a significant and pervasive issue among upper limb amputees, severely impacting their quality of life. The literature delineating prevalence of upper versus lower limb amputations is limited, but the prevalence of total amputations in the United States is estimated to reach 3 million individuals by …

18 years of age All Phase N/A
N Nathalie André-Obadia, Doctor

Cortical Stimulation by Direct Current for the Treatment of Chronic Pain : Pilot-study of a Stimulation Device at Home

The purpose of this study is to confirm the analgesic effect of tDCS in neuropathic chronic pain, to estimate the importance and the duration of this effect, and to improve its efficiency by the use at home. It is established that the repetition of the sessions of cortical stimulation over …

18 - 80 years of age All Phase N/A

Effects of Rigid Taping in Acromioclavicular Joint Degeneration

This study will examine whether rigid taping applied to the acromioclavicular (AC) joint can reduce shoulder pain and improve shoulder function in people with AC joint degeneration. Participants with shoulder pain and a confirmed diagnosis of AC joint degeneration will be randomly assigned to one of two groups: (1) rigid …

18 - 65 years of age All Phase N/A
E Eric Johnson, PharmD

Ketamine in Patients Undergoing TEVAR Procedures Receiving NCI

The objective of this study is to identify the opioid-sparing effects, and pain-reduction potential of low dose, sub-dissociative ketamine on patients undergoing thoracic endovascular aortic repair (TEVAR) procedures receiving naloxone continuous infusion (NCI).

18 - 90 years of age All Phase 2
D Daniela B Advis

Total Periarticular Infiltration Vs Posterior Periarticular Infiltration Plus PENG Block for Hip Analgesia

In a recent study, direct periarticular local anesthetic infiltration (PAI) showed a greater incidence of early quadriceps weakness (33% at 3 hours and 13% at 6 hours) than pericapsular nerve group block (PENGB) in total hip arthroplasty (THA) but, in turn, demonstrated a statistically significant better pain control. Additionally, PENGB …

18 - 80 years of age All Phase N/A
V Victor Contreras, MSN

CORA-Q15: Continuous vs. Single-injection Interscalene Block on QoR-15 in Outpatient Rotator Cuff Surgery

The purpose of the study will be to compare the efficacy of single-injection interscalene block versus continuous interscalene block on the quality of recovery in patients undergoing outpatient arthroscopic rotator cuff repair surgery. The participants will: Be randomized to receive either a single-injection interscalene block or continuous infusion via an …

18 - 75 years of age All Phase 4

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