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inflammation Clinical Trials

A listing of inflammation medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 513 clinical trials
A Andrew H Miller, MD

Inflammation and Depression in People With HIV

The purpose of this 10-week, double-blind, placebo-controlled study is to determine whether inflammation impacts reward and motor neural circuitry to contribute to depressive symptoms like anhedonia and psychomotor slowing in people with Human Immunodeficiency Virus (HIV) and depression. Sixty male and female patients with HIV who have depression, anhedonia and …

18 - 65 years of age All Phase 2
L Lacy Alexander, Ph.D.

Endometriosis and Microvascular Dysfunction: Role of Inflammation

The purpose of this study is to better understand the underlying mechanisms associated with elevated cardiovascular disease risk in women with endometriosis, and to measure the effectiveness of emerging endometriosis treatments on outcomes specific to cardiovascular dysfunction. Epidemiologic data demonstrate a clear association between endometriosis, reproductive risk factors, inflammation and …

18 - 45 years of age Female Phase N/A
C Claudia Salazar, BS

Macrophage Regulation of Ozone-Induced Lung Inflammation

The purpose of this research study to understand how prior respiratory infections affect the susceptibility to lung inflammation following environmental exposures.

18 - 55 years of age All Phase 1
P Peter Rosenberger, MD

Inflammation During ECMO Therapy and ECMO Weaning

The goal of this interventional clinical trial is to compare patients who undergo ECMO therapy for treatment of acute respiratory distress syndrome (ARDS) and a randomized into one of two possible weaning strategy groups. Group 1: Weaning from ventilator occurs before ECMO weaning. Group 2: Weaning from ECMO occurs before …

18 years of age All Phase N/A
S Sabina Frljak, MD, PhD

Cardiovascular Genistein Therapy for Heart Failure Inflammation

This Phase 1b/2a open-label study is designed to assess the safety and efficacy of genistein in patients with heart failure (HF). The investigation will focus on its impact on inflammatory and cardiometabolic biomarkers, as well as its effects on cardiac function and exercise capacity. Blood samples will be collected at …

40 - 80 years of age All Phase 1/2
R Rosa Maria Casas, Dr

Peanut Consumption on Cognitive, Weight, and Inflammation

A multi-school, two-arm parallel cluster-randomized controlled trial will be conducted in 200 healthy young adolescents from Barcelona (Spain) to evaluate the effect of peanut consumption on cognitive performance, weight management and inflammation. Schools willing to participate will be randomly assigned to either the intervention or the control group. After the …

10 - 12 years of age All Phase N/A
A Annamaria Cattaneo

Effect of Minocycline on Inflammation in Depressed Patients

The study aims to evaluate or to assess: An improvement in the peripheral inflammatory levels in depressed patients after 8 weeks of treatment with Minocycline in addition to their current antidepressant treatment; Any improvements in depressive symptoms after 8 weeks of treatment with Minocycline given as adjuvant to the current …

25 - 45 years of age All Phase 2
K Katarina Ejeskär, PhD

Gfree - For Improved Blood Sugar and Reduced Inflammation.

The goal of this clinical trial is to reduce inflammation and improve glycemic control in healthy volunteers, parents, as well as children, adolescents and adults with or without diabetes. The main questions it aims to answer are: • does a reduction wheat gluten improve glycemic control and/or inflammatory biomarkers • …

6 years of age All Phase N/A
E Erin Schubert

Imaging Sex Differences in Smoking-Induced Pulmonary Inflammation

The purpose of this research is to measure the extent of lung inflammation between different groups of participants using a radioactive tracer called [18F]NOS. A radioactive tracer is a type of imaging drug that is labeled with a radioactive tag and injected into the body.

18 - 45 years of age All Phase 1
R Rajagopal V Sekhar, MD

Glutathione, Brain Metabolism and Inflammation in Alzheimer's Disease

Alzheimer's disease (AD) is associated with significant, progressive cognitive decline. Key defects in mitochondrial fuel metabolism insulin resistance, inflammation and decreased brain glucose uptake are linked to AD. This trial will investigate the effects of supplementing glycine and N-acetylcysteine vs. alanine as placebo on these defects in AD, and examine …

55 - 85 years of age All Phase N/A

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