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inflammation Clinical Trials

A listing of inflammation medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 513 clinical trials
E Etienne CANOUI, MD

Complex Ocular Infection, Optimization of Microbiological Diagnosis

The purpose of this study is to evaluate the impact of different technique to optimize the microbiological diagnosis of the COI. Metagenomic for the endophtalmitis Multiplex polymerase chain reaction for corneal abscesses

18 years of age All Phase N/A
J Jakob Hytting, MD

Impact of Inflammatory Indexes and Gene Scores in Prediction of Atrial Fibrillation Recurrence Following Electrical Cardioversion

Because of the high recurrence rates following electrical cardioversion and high morbidity in AF patients there is a need to explore prediction models for AF recurrence following ECV. Previous studies have primarily focused on high-sensitivity CRP (hsCRP), CRP, and IL-6, while other inflammatory indexes and gene scores might hold greater …

18 years of age All Phase N/A

Spectroscopic Evaluation of Middle Ear Infection

Otitis media is more common in young children and it is estimated that 75% of all children experience at least one episode before the age of three. Otitis media is one of the common pediatric diagnoses and recurrent episodes account for the most commonly performed surgical procedure. Despite this a …

- 21 years of age All Phase N/A

Evolution of HIV Reservoir, Inflammation and Microbiota Footprint of PLWH Switching to Long-acting Injectable Treatment Compared to Patients on Oral Dual or Triple Anti-integrase-based Therapy

In the last 40 years of HIV history, we have managed to attain most of our therapeutic objectives, namely virological suppression of most patients and sufficient immune reconstitution. Still, immune activation and inflammation persist and even if they decrease on ART (AntiRetroviral Treatment), they do not disappear and may be …

18 years of age All Phase N/A
F Francesca Palandri, MD, PhD

Evaluation of Inflammatory Markers in ph Negative Myeloproliferative Neoplasms: Impact on Outcome and Response to Therapy. Multicenter Retro-prospective Observational Study. The INFLA-ME (INFLAmmation in Myeloproliferative Disease) Study.

This study aims to observe inflammatory biomarkers and their trend over the history of the disease in patients suffering from MPN Ph negative; it also wants to identify any correlations between the aforementioned biomarkers and disease outcomes, considering first of all the occurrence of thrombo-haemorrhagic events and the evolution in …

18 - 99 years of age All Phase N/A
S Smith Aubrey

Investigating the Link Between Type 2 Immunity and NAFLD in Human Obesity

This study is being done to better understand the relationship between inflammation in adipose tissue (AT), abnormal deposition of fat around the liver and how this affects its appearance and function and ultimately insulin resistance.

30 - 70 years of age All Phase N/A
F Fermín Sánchez-Guijo Martín, PhD MD

Study of the Hematopoietic Niche and the Role of Inflammation in the Pathophysiology of Cytopenias After CAR-T Cell Therapy: Potential of Therapies Directed to Repair the Bone Marrow Microenvironment

Immunotherapy with chimeric antigen receptor T-cells (CAR-T) has revolutionized the treatment of oncohematological diseases and its applications in solid tumors and non-neoplastic diseases are advancing. Cytopenias after CAR-T therapy are the most frequent complication in the medium and long term after treatment, they are a cause of morbimortality, and there …

18 years of age All Phase N/A
O Olivier O. SOMBIE, Attaché de Recherche

Validation and Simplification of the Retinol Isotope Dilution Technique in Burkinabe Schoolchildren

Two cross-sectional, repeated-pass, community-based studies will be carried out during the school year. The first study will be conducted from November to December. This period corresponds to the end of the rainy season and the end of the mango season, which is one of the main sources of vitamin A …

7 - 12 years of age All Phase N/A

Prospective Study of White Blood Cells

The purpose of this study is to investigate white blood cells from volunteering donors to support the development of engineered regulatory T cell therapies.

years of age All Phase N/A
R Reena Kartha, PhD

Oxidative Stress and Inflammatory Biomarkers in Gaucher Disease

The objective of this study is to evaluate oxidative stress and/or inflammation in patients with Gaucher disease type I using a series of biomarkers and correlate with measurements of currently used diagnostic biomarkers.

18 - 75 years of age All Phase N/A

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