Advanced Filters
noise

inflammation Clinical Trials

A listing of inflammation medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 513 clinical trials

Vaccine Immunity and Inflammation in the Aging Person Living With HIV

This study will track immune responsiveness to conjugate pneumococcal vaccines over time to help determine how long protection from this vaccine lasts in individuals with chronic medical conditions (in this study - HIV) and with age.

18 years of age All Phase 4
C Claire Goebel, B.S.

Role of Inflammation in Vascular Phenotype Associated with E-cigarette Use

The use of electronic nicotine delivery systems, or e-cigarettes - colloquially referred to as "vaping" - in the United States has increased exponentially since their introduction to the US market in 2007. Prevalence of ever and current e-cigarette use is highest among teenagers and young adults with 16-28% of this …

18 - 24 years of age All Phase N/A
M Matthew J Roberts, PhD

EXercise Therapy in Axial SpA, Inflammation and Biologic Therapy (ExTASI-B)

The goal of this randomised controlled trial study is to investigate whether exercise (brisk walking, equal to 13 on a rating of perceived exertion scale; somewhat hard) can be used as an adjuvant therapy for people living with axial spondyloarthritis and taking biologic medications to further improve their quality of …

18 years of age All Phase N/A
M Manuel Morrens

INflammation-based Stratification for Immune-Targeted Augmentation in Major Depressive Disorder

This is a randomised, double-blind, placebo-controlled clinical trial in which patients with major depressive disorder will receive augmentation through minocycline (MCO), celecoxib (CXB) or placebo.

18 - 65 years of age All Phase 3
P Pei-Chen Chang, MD, Master

Omega-3 Fatty Acids, Inflammation, Gut Microbiota in Youth With Depression

This is a 12 week double blind RCT aimed to investigate the role of omega-3 fatty acids in patients with major depressive disorder

13 - 18 years of age All Phase N/A
S Sevim Şenol Karataş, MD

Effects of Spinal vs General Anesthesia on Systemic Inflammation in PCNL

This observational study aims to compare the effects of spinal and general anesthesia on perioperative systemic inflammatory response in patients undergoing percutaneous nephrolithotomy (PCNL). Systemic inflammatory indices derived from routine complete blood count parameters, including Systemic Immune-Inflammation Index (SII), Systemic Inflammation Response Index (SIRI), Aggregate Index of Systemic Inflammation (AISI), …

18 years of age All Phase N/A
M Mona Mashayekhi, MD

The Effect of SGLT2 Inhibition on Adipose Inflammation and Endothelial Function

Obesity is associated with increased cardiometabolic disease risk due, in part, to heightened chronic inflammation arising from adipose tissue. There are no current targeted therapies to prevent or reverse the chronic inflammation of obesity, and a better understanding of these inflammatory pathways in humans is key to future therapeutic interventions. …

18 - 70 years of age All Phase 1/2
M Michele Paolantonio, MD; DDS

The Role of Diet in Periodontal Inflammation: A Controlled Clinical Study

Diet can influence the body's healing and repair mechanisms. A dietary imbalance obviously cannot trigger periodontal disease in the absence of a primum movens, which is bacterial plaque. However, it can condition its severity and extent by altering the permeability of the oral mucosa, the effectiveness of the immune response …

18 years of age All Phase N/A
E Erik Ehinger, MD

Effect of Salovum® on Pressure, Oxygen and Inflammation in Glioblastoma

The objective of this clinical trial is to investigate the effects of Salovum®, an egg yolk powder enriched with the endogenous protein antisecretory factor, in participants undergoing diagnostic biopsies for suspected glioblastoma. The primary questions the trial seeks to answer are: Will Salovum® reduce intratumoral pressure? Will Salovum® influence the …

18 - 75 years of age All Phase 2
C Clifton Carey

Miniscrew Stability and Peri-implant Inflammation When Precoated K21 vs Ethanol Control

To determine if coating miniscrews with K21 would increase the success rate of orthodontic miniscrews by reducing adjacent tissue inflammation.

12 years of age All Phase N/A

Simplify language using AI