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in-vitro-fertilization Clinical Trials

A listing of in-vitro-fertilization medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 62 clinical trials
M Marwa O. Elgendy, Associate professor

Growth Hormone and Dehydroepiandrosterone Role in Vitro Fertilization

The goal of this study is to evaluate the role of Somatropin and Dehydroepiandrosterone (DHEA) on ovarian reserve parameters and intracytoplasmic sperm injection (ICSI) outcome in poor ovarian responder. The main question it aims to answer is: Which intervention is more effective in increasing number and size of follicles? Participants …

18 - 35 years of age Female Phase 2/3
N Noam Smorgick, Prof

Comparison of Surgical Management of Early Pregnancy Loss by Suction Curettage Versus Hysteroscopy in Patients Undergoing In-vitro Fertilization (IVF)

Early pregnancy loss occurs in \~15% of pregnancies. The treatment options include surgical uterine evacuation by suction curettage, medical management with misoprostol, or conservative management without interventions. The advantages of surgical management include quick resolution of the pregnancy and avoidance of heavy vaginal bleeding, while the disadvantages include retained products …

18 - 50 years of age Female Phase N/A

BEst Size for Ovulation Triggering in Poseidon 4 Patients (BEST 4 Study)

This observational clinical study aims to determine the optimal timing of ovulation triggering in women aged 35 and above with poor ovarian reserve. For this purpose, cases undergoing ovarian stimulation for assisted reproductive treatment and planned final oocyte triggering will be evaluated in two separate groups: \*\Experimental Group\\: Final oocyte …

35 - 44 years of age Female Phase N/A
D Dario Lot, Biology

Day-4 Embryo Defragmentation: Blastocyst Rate and clInical Outcomes

Background Embryo fragmentation is one of the main morphological parameters assessed during in vitro culture in assisted reproductive technology (ART). The presence of anucleate cytoplasmic fragments is commonly observed in human embryos and may negatively affect developmental potential and clinical outcomes. Embryo defragmentation at early stages (Day 2-3) is an …

20 - 42 years of age Female Phase N/A

hCG Priming in Women With Diminished Ovarian Reserve

The aim of this randomized controlled trial is to further examine the possible effects of low dose human chorionic gonadotropin (hCG) priming for eight weeks in women with diminished ovarian reserve (DOR) undergoing in vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI). The investigators want to retest the findings of our first …

18 - 40 years of age Female Phase 3
T Tasha Newsome

SISTER: Sibling Oocyte Insemination With Frozen Sperm From Third Party Donors: Evaluation of Reproductive Techniques

The goal of this clinical trial is to learn whether two different methods of helping eggs and sperm join-intracytoplasmic sperm injection (ICSI) and conventional in vitro fertilization (IVF)-lead to better embryo development when using frozen donor sperm in people who do not have male fertility problems. The main questions it …

years of age Female Phase N/A
U Ursula Gobrecht-Keller, MD

Mechanisms of Maternal Immune Tolerance in Early Pregnancy

This study explores the mechanisms of maternal immune tolerance in early pregnancy by characterizing immune cell profiles and functional pathways during the first trimester. The goal is to identify immunological factors that support healthy gestation and prevent complications such as miscarriages.

18 years of age Female Phase N/A
J Jonalyn Edades

Effect of Antioxydant-enriched Media on Blastocyst Euploidy Rates.

One of the most sensible factors in IVF culture conditions is the susceptibility of gametes and embryos to an induced increase in reactive oxidative species (ROS) caused by the artificial environment. This study aims to evaluate the impact of using antioxidant-supplemented media during culture to evaluate embryo ploidy rates in …

18 - 43 years of age All Phase N/A
A Alicia L Broussard, PhD

Ovarian PRP Injections for Improved Embryo Quality Using Embryo Quality Score

Patients will have ovarian PRP treatments and embryo development will be observed using time-lapse imaging and AI software.

18 - 47 years of age Female Phase N/A
I Ignacio Rodriguez, MSc

Effect of Semaglutide on Embryo Quality in Overweight and Obese Patients Undergoing In Vitro Fertilization.

This is a randomized, controlled clinical trial with a two-sided superiority hypothesis. The study evaluates whether a 12-week pre-treatment with semaglutide prior to ovarian stimulation improves the number of good-quality blastocysts in overweight and obese women undergoing in vitro fertilization (IVF), compared to no pre-treatment.

18 - 38 years of age Female Phase 4

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