Advanced Filters
noise

Intermittent Explosive Disorder Clinical Trials

A listing of Intermittent Explosive Disorder medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 36 clinical trials

Pimavanserin and Aggression and Social Cognition.

The investigators are studying how certain drugs can reduce anger outbursts in people with anger problems. In this study the investigators seek to determine if a single 34 mg (two 17 mg tablets) oral dose of the 5-HT2a receptor blocker, pimavanserin, will reduce aggressive responding in individuals with impulsive aggression …

21 - 55 years of age All Phase 2
E Ephrem Fernandez, Ph.D.

Maladaptive Anger Treatment

From a psychoevolutionary perspective, anger is a universal emotion that can serve the function of making us aware of wrongdoing and motivating us to undo/correct the wrongdoing. However, it is well recognized in clinical psychology that anger can be maladaptive, often causing distress and impairment in various areas of day-to-day …

18 - 65 years of age All Phase N/A
E Emil Coccaro, M.D.

Neural Correlates During Alcohol Intoxication

Alcohol intoxication is responsible for a large proportion of violent crime/assault and personal injury in our society. While a number of variables have been associated with alcohol-related aggression, high trait aggression and impaired executive function have been identified as key factors. Both Alcohol Use Disorder (AUD) and Impulsive Aggression behavior …

21 - 55 years of age All Phase 2
C Cynthia Dougherty, ARNP, PhD

Effectiveness of Exercise After an ICD

This study will test an exercise intervention (E-ICD) following an implantable cardioverter defibrillator.

18 years of age All Phase 2/3
J Jakob Luker, MD

S-ICD Implantation: US Based Pilot Study

This trial investigates two key aspects of the S-ICD implantation process. 1) For S-ICD implantation a pre-operative x-ray-based assessment of the anatomy and location of the heart is required. This study seeks to investigate the feasibility of US to potentially replace the need for x-ray 2) The PRAETORIAN score predicts …

years of age All Phase N/A
C Cynthia Dougherty, ARNP, PhD

Self-Management Interventions After an ICD Shock

This study, "Biobehavioral Intervention to Reduce PTSD Symptoms After an ICD Shock," addresses a critical need in cardiology care by describing the feasibility and acceptability of a timely, highly promising, electronically-delivered intervention for patients who have recently received an ICD delivered shock. The study intervention and outcomes are designed to …

18 years of age All Phase N/A

ColoSeal™ ICD System Safety and Feasibility Study

The purpose of this clinical investigation is to evaluate the safety and feasibility of the ColoSeal ICD System in a prospective, multicenter, single-arm study. The ColoSeal ICD System is intended to be used to protect a damaged segment of colon such as a surgical anastomosis, anastomosis leak, or perforation from …

18 - 70 years of age All Phase N/A
D Debi Everidge

Reduction of Myopotential Interference With Smart Pass in S-ICD Patients

This study is enrolling participants who are already implanted with a S-ICD device ( subcutaneous ICD), and are undergoing a routine outpatient clinic follow up appointment to have their S-ICD checked. The aim of the study is to see if a feature in the device can recognize muscle movement and …

18 years of age All Phase N/A
P Paul Gould, A/Prof

BIO|CONCEPT.CorSky, First in Human Study for the CorSky ICD Family

The goal of this exploratory study is to test the preliminary safety and product performance of the new CorSky ICD family in subjects that require an ICD or cardiac resynchronization therapy with defibrillation (CRT-D). The study will be conducted at sites in Australia and New Zealand. It is planned to …

18 years of age All Phase N/A
A Andrada D Neacsiu, PhD

Neurostimulation Versus Therapy for Problems With Emotions

The primary goal of this clinical trial is to evaluate the unique neural and behavioral effects of a one-session training combining emotion regulation skills training, with excitatory repetitive transcranial magnetic stimulation (rTMS) over the dorsolateral prefrontal cortex (dlPFC). The secondary aim is to identify key changes in the emotion regulation …

18 - 55 years of age All Phase N/A

Simplify language using AI