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barretts-esophagus Clinical Trials

A listing of barretts-esophagus medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 113 clinical trials
A Anna Gao, RN

Pilot Study for OCT Guided In Vivo Laser Capture Microdissection for Assessing the Prognosis of Barrett's Esophagus

The investigators have developed a new technology, termed in-vivo laser capture microdissection (IVLCM), that addresses the limitations of endoscopic biopsy for screening for BE and provides targeted genomic profiling of aberrant tissue for more precise prediction of EAC risk. The device is a tethered capsule endomicroscope (TCE) that implements optical …

18 years of age All Phase N/A
A Anna Gao, RN

Pilot Study for TCE Imaging of the Esophagus Using an OFDI Capsule With a Compact Imaging System

The goal of this research is to test a distal scanning capsule and a compact redesigned version of the OFDI imaging system in healthy and BE subjects to assess ease of use, safety and feasibility in preparation for its use in a multicenter clinical trial.

18 - 70 years of age All Phase N/A
D Dr. Fredrik Klevebro

A Study of Barrett's Esophagus Patients to Investigate Quality of Life and Fear of Cancer, and Optimize a Risk Model Based on Biomarkers and New Technologies to Better Predict the Development of Cancer

This study serves, in part, to prepare for a future large cohort study. The goal of the study is: The collection of various tissue samples (blood, biopsies and "esophageal brushes") and their analysis. To set up standardized methods for different genetic analyses (DNA-FISH and so-called single cell sequencing) on the …

18 years of age All Phase N/A
N Nikolaus E. Wolter, MD

Be Sweet to Babies During Nasolaryngoscopy

The investigators want to know if sugar water containing 24% sucrose is helpful in reducing pain in babies during scopes.

1 - 12 years of age All Phase N/A

A Study to Assess the Safety, Tolerability, and Efficacy of IMVT-1402 in Participants With Cutaneous Lupus Erythematosus (CLE)

The primary purpose of this study is to evaluate the efficacy, safety, and tolerability of IMVT-1402 in participants with Cutaneous Lupus Erythematosus. The study will consist of 3 periods: Period 1: eligible participants will be randomized 1:1 to IMVT-1402 or placebo SC QW for 12 weeks. Period 2: participants who …

18 years of age All Phase 2
Y Ying Nan Tsai, M.D

The Prevalence, Risk Factors and Optimal Biopsy Protocol of BE

Detections of goblet cells and dysplasia are crucial for diagnosis and determining the surveillance program of Barrett's esophagus (BE). However, the optimal biopsy numbers and their yield rates of intestinal metaplasia (IM) and dysplasia are still uncertain, especially in Asia. The aim of this study was to determine the optimal …

20 years of age All Phase N/A
L Laureen Smith, PhD

Mentoring to be Active for Rural Appalachia Children

The innovative MPBA+F begins with peer-to-peer mentoring followed by structured parental/family support for long-term reinforcement of PA behaviors. Building and reinforcing skills, MPBA+F mitigates resource stressors and strengthens protective factors by providing culturally appropriate knowledge and skills to improve the sustainability of physical activity at home without the use of …

11 years of age All Phase N/A
A Ane Simony

What Laxative Should be Used After Hip Fracture Surgery?

To conduct a randomized clinical trial to determine how best to prevent constipation after hip fracture surgery using laxatives.

65 - 110 years of age All Phase 4
O Osmani Placencia, MD

OLE Therapy With BE Patients in Home Care Study

The study will examine how the performance of Oscillating Lung Expansion (OLE) therapy affects the respiratory health of patients with Bronchiectasis (BE). The patient will use the BiWaze Clear system for their airway clearance therapy, instead of their previously prescribed therapy. BiWaze Clear is an FDA-cleared respiratory therapy for assisting …

5 - 85 years of age All Phase N/A
J Junelyn Floyd

BE WELL With Migraine: Brain Education and WELLness With Migraine

The goal of this randomized clinical trial is to evaluate two different non-drug, virtual treatment options designed to improve the lives of patients with migraine. Both interventions involve 8 weekly sessions and an online platform with additional content and learning. Participants can stay on all their medications during this study. …

18 years of age All Phase N/A

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