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mitral-valve-regurgitation Clinical Trials

A listing of mitral-valve-regurgitation medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 214 clinical trials
Y Yibin Xie, Ph.D

CANF-Comb-II PET-MR in Atherosclerosis Multisite

The goal of this observational study is to learn more about plaque biology in asymptomatic carotid artery stenosis (ACAS) patients through imaging. The main questions it aims to answer are To determine the ability of 64Cu-CANF-Comb positron emission tomography (PET) to risk stratify ACAS patients for stroke event, to include …

18 years of age All Phase N/A
J Jennifer Moussa

PET/MR in Post Stroke Cardiac Inflammation Study

Patients with stroke have a 25x higher risk of cardiovascular complications within the first 30 days of the event compared to individuals without stroke. The mechanisms behind these complications are not well understood. Evidence suggests that inflammation plays a central role. With the present proof-of-concept prospective cohort study, the investigators …

18 years of age All Phase N/A
C Charlton C Starcke

PET/MR for Characterization of Renal Masses (RMs)

The frequency of kidney tumors found incidentally on imaging studies performed for unrelated reasons continues to increase leading to more surgeries and ablations for the treatment of renal masses thought to be cancer. However, about 20% of these masses are not cancerous and do not require treatment. Many cancerous kidney …

18 years of age All Phase N/A

Response Assessment During MR-guided Radiation Therapy for Glioblastoma

The study seeks to assess the response of glioblastoma multiforme to treatment using weekly low field (0.35 T) MR-images of the brain at a MRIdian® linac system during standard radiotherapy at the same system. A total of 20 patients in a single arm will be recruited for this investigation. The …

18 years of age All Phase N/A
M Mirjam Alsaker, md phd

The EMINENCE Study - PET/MR Imaging of Head Neck Cancer

Head and neck cancers (HNC) often receive radiotherapy as part of their treatment. However, unacceptable failure rates and severe side effects remain a challenge. The improvements in radiotherapy are closely related to improvements in medical imaging. Functional imaging, where intratumoural characteristics such as tumour oxygenation, metabolism, and blood vessel function …

18 years of age All Phase N/A
L Lukas Imbach, PD Dr. med.

High-field MR Imaging in Migraine, Visual Snow and Epilepsy

In this project, the aim is to recruit patients with drug resistant epilepsy and those suffering from migraine. Interestingly, patients suffering from epilepsy are also more often reporting to suffer from migraine. The pathobiology is understudied, but it is believed that both etiologies results from brain networks changes. A clinical …

18 - 65 years of age All Phase N/A
W Wenli Lu

A Fast, Quiet, Artificial Intelligence-based PET/MR Solution for Paediatric Diseases

To investigate the feasibility of deep learning-assisted rapid silent PET/MR in pediatric applications.

- 18 years of age All Phase N/A
X Xiao Chen, Ph.D

PET/MR Evaluation of Regression Grading After Neoadjuvant Therapy for Rectal Cancer

This project aims to evaluate the role of 18F-FAPI combined with 18F-FDG PET/MRI imaging in quantitatively and accurately evaluating the grading of rectal cancer after SCRT neoadjuvant therapy in patients with advanced rectal cancer as the research object, with postoperative histopathological analysis as the reference index, and to assess the …

18 years of age All Phase N/A
H Holly Wrighht

Molecular Imaging of Inflammation in Parkinson's Disease Using LPS and TSPO-PET/MR

It is not known what causes Parkinson's disease and what makes it worsen over time. Research conducted in the past few years has highlighted the possible role of inflammation on this process but its actual mechanisms are still obscure. In this study, the investigators aim to gain understanding on how …

50 - 85 years of age All Phase N/A
X Xiao Chen, Ph.D

Role of FAPI PET/MR Combined With Gadoxetate Disodium in Assessing Hepatic Malignancies

This study aimed to prospectively evaluate the utility of fibroblast activation protein inhibitor (FAPI) positron emission tomography (PET)/magnetic resonance (MR) combined with gadoxetate disodium in patients with clinical suspected hepatic malignancies (lesion diameter ≤ 3.0cm), with histopathological findings obtained from biopsy or resected surgical specimens, or follow-up results as reference …

18 years of age All Phase N/A

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