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Aneurysm Clinical Trials

A listing of Aneurysm medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 262 clinical trials
D Dr hab.n.med Michał Zawadzki

NEUROvascular NAVigation With Remotely Controlled Deflectable Guidewire, Study II (NeuroNAV Study II)

The aim of the study is to confirm the safe and successful use of the SmartGUIDE guidewire, when used in neuro interventions. The performance of the SmartGUIDE guidewire in terms of safe and successful navigation within the neurovasculature will be compared to standard of care guidewire on the market.

18 years of age All Phase N/A
D David Kuwayama, M.D, MPA

Physician-Modified Fenestrated and Branched Aortic Endografting for TAAA

The primary clinical objective of this study is to evaluate the safety and effectiveness of a physician-modified, fenestrated and branched aortic endoprosthesis for the treatment of thoracoabdominal aortic aneurysms (TAAAs). The goal of the primary analysis is to demonstrate both the safety and effectiveness of using a physician-modified fenestrated Cook …

50 - 95 years of age All Phase N/A
P Prof. Dr. Aymeric Rouchaud

NEUROvascular NAVigation With Remotely Controlled Deflectable Guidewire, Study I (NeuroNAV Study I)

The aim of the study is to confirm the safe and successful use of the SmartGUIDE guidewire, when used in neuro interventions. The performance of the SmartGUIDE guidewire in terms of safe and successful navigation within the neurovasculature will be compared to standard of care guidewire on the market.

18 years of age All Phase N/A
P Peter C Rudberg, M.D. Ph.D.

Delayed Cerebral Infarction Beyond Endoluminal Spasmolysis and Induced Hypertension

An observational study of patients with emerging or established severe cerebral vasospasm after subarachnoid haemorrhage, employing multimodal neuromonitoring.

18 years of age All Phase N/A
D Dmitri S. Panfilov, MD, PhD

Full Sternotomy vs Mini-sternotomy for Ascending Aortic Pathology

This study investigates outcomes after hemiarch repair in patients with chronic ascending aortic disease. The patients will be divided into two groups according to surgical approach: 100 patients will undergo hemiarch repair via full sternotomy (FS group) and 100 patients will receive hemiarch repair via J-shaped mini-sternotomy (MS group). Early …

18 - 80 years of age All Phase N/A
A Alessandro Pini, MD

Genetic Aortic Diseases and Cardiovascular Complications. An Observational Survey of Risk Factors.

The aim of this observational study is to define the behavioural and cardiovascular risk factor profiles of patients with genetic aortopathies. The main questions it aims to answer are: How do the interconnections between lifestyle, stress, psychological condition, perception of illness, and state of health influence each other in this …

14 - 60 years of age All Phase N/A
Z Zheng Wan, M.D.

Investigation of Protein Heterogeneity in Extracellular Vesicles Derived From Different Human Blood Circulatory Regions

The goal of this observational study is to learn about the protein heterogeneity in extracellular vesicles (EVs) derived from different human blood circulatory regions of patients with ruptured or unruptured intracranial aneurysms. The main objectives are: Reveal the proteomic heterogeneity of EVs in different blood circulatory regions of the human …

18 - 60 years of age All Phase N/A
J Juan Manuel Sanchís García

Efficacy of Biomarkers and CEUS Versus CTA in AAA Follow-up Post-EVAR

This prospective observational study evaluates the efficacy of contrast-enhanced ultrasound and biomarker determination in the follow-up of patients with abdominal aortic aneurysm (AAA) treated with Endovascular Aneurysm Repair (EVAR). Currently, computed tomography angiography (CTA) is the standard for follow-up, although it has disadvantages such as radiation exposure and the use …

18 years of age All Phase N/A
S Stanislav Sirakov, Prof.

LUMENS-1 EU EFS CIP

The primary objective of this clinical investigation is to evaluate the early safety and feasibility of the LuSeed Aneurysm Embolization System for treating unruptured intracranial aneurysms (IA). This is a prospective, single-arm, open-label, multi-center, interventional study, screening patients approved for treatment of unruptured IAs based on national or international guidelines. …

18 - 80 years of age All Phase N/A
D Daniel Roy, MD

Comprehensive Aneurysm Management Trial

The uncertainty regarding the management of Unruptured Intracranial Aneurysms (UIAs) has not progressed in the last 30 years. The fundamental ethical basis for this study is that physicians should only offer a risky preventive treatment when it has been shown to be beneficial. Before that, such treatment should be offered …

18 years of age All Phase N/A

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