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Kidney Failure Clinical Trials

A listing of Kidney Failure medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 595 clinical trials

Nafamostat Efficacy in Phase 3 Registrational CRRT Study

A prospective, randomized, placebo-controlled clinical study to investigate the safety and efficacy of Niyad (nafamostat mesylate) for anticoagulation of extracorporeal blood circulating through a dialysis filter in patients undergoing CRRT who cannot tolerate heparin or are at higher risk for bleeding.

18 - 80 years of age All Phase N/A
Y Yali Ge, Doctor

Application of CLCVP Technique in Early Intervention of CSA-AKI

The goal of this clinical trial is to learn about in postoperative acute kidney injury in cardiac surgery. The main questions it aims to answer are: Controlled low central venous pressure (CLCVP) technique can reduce the occurrence of cardiac surgery-associated acute kidney injury (CSA-AKI) by reducing venous congestion and increasing …

18 years of age All Phase N/A
J Jonathan Assistant Professor, PhD

Effects of Creatine Supplementation on Cognitive Measures and Markers of Acute Kidney Injury After Exercise in the Heat

The goal of this clinical trial is to learn if one week of creatine monohydrate supplementation alters inflammation, markers of acute kidney injury (AKI) risk, and cognitive performance in active, young, healthy volunteers. The main questions it aims to answer are: Does one-week of creatine supplementation alter urinary markers of …

18 - 45 years of age All Phase N/A
M Marlies Ostermann, MD, PhD

WISDOM UK: Low Dose-intensity Versus Standard Dose-intensity CRRT in Critically Ill Patients

Acute kidney injury is a potentially life threatening condition which affects 1 in 2 patients in the Intensive Care Unit (ICU). Patients often need dialysis treatment, also called renal replacement therapy. Renal replacement therapy is a treatment that removes toxins and excess fluid from the blood stream. It consists of …

18 years of age All Phase N/A
K Kerry Horne Dr

Improving Patient Assessment After Acute Kidney Injury (AKI)

The goal of this clinical trial is to improve patient care after acute kidney injury (AKI). It has three related parts. The main questions it aims to answer are: Is creatinine or cystatin a more reliable assessment of kidney function after AKI? What are the experiences of patients after AKI? …

18 - 85 years of age All Phase N/A
C Charles S Cox, Jr., Dr.

Allogeneic HB-adMSCs vs Placebo for the Treatment of Acute Kidney Injury

This study aims to investigate, through the collection of valid scientific evidence necessary to determine safety and effectiveness, the potential use of Allogeneic Hope Biosciences Adipose-derived Mesenchymal Stem Cells (HB-adMSCs) to prevent progression of trauma-induced Acute Kidney Injury (AKI).

18 - 75 years of age All Phase 1/2
Z Zarbock

Nephroprotective Measures in Critically Ill Patients With Moderate/Severe Acute Kidney Injury

This study investigates to which extent recommended nephroprotective measures are implemented in critically ill patients with moderate or severe acute kidney injury.

18 years of age All Phase N/A
N Natalie Goodman, BA

Theophylline Prophylaxis During Hypothermia to Limit Neonatal Nephron Damage

Acute kidney injury is a significant complication for infants who experience hypoxic ischemic encephalopathy, being associated with increased rates of death and prolonged hospitalization. This pilot study of theophylline administration soon after birth for the prevention of kidney injury will lay the foundation for the conduct of a larger clinical …

- 18 years of age All Phase 1/2
L Lars M Ytrebø, MD PhD

Investigations Into Sepsis-associated Acute Kidney Injury

In this study the investigators would like to study systemic and regional disturbances in patients with sepsis-associated acute kidney injury and in healthy controls undergoing laparoscopic abdominal surgery. Specifically study metabolic, hemodynamic and oxygen transport variables.

18 - 100 years of age All Phase N/A
R Reid Whitlock, MSc

CKD Specific Telemonitoring Platform to Minimize Adverse Outcomes in High Risk CKD Patients

The main purpose of this trial is to determine whether the addition of the VIEWER virtual care platform to usual care will lead to a reduction in composite emergency department (ED) visits and/or hospitalizations/or increase the perceived safety of virtual care among patients and providers.

18 years of age All Phase N/A

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